Results 111 to 120 of about 392,157 (303)

Les métiers de la ville en débat

open access: yes, 2018
Atelier participatif (source : Agence Ville ouverte) En France comme ailleurs, délimiter le périmètre des métiers de la ville est une question presque toujours controversée.
Cybergeo Conversation
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Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Watch, listen and learn: Observing children’s social conduct through their communication [PDF]

open access: yes, 2011
This paper argues for the use of conversation analysis (CA) and membership categorisation analysis (MCA) (Sacks, 1992) to investigate children’s social conduct.
Bateman, Amanda
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ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Migrations et sélections de populations

open access: yes, 2019
Le CGET vient de publier le rapport 2018 de son Observatoire des territoires, qui traite des mobilités résidentielles en France, mesurées précisément entre 1968 et 2014.
Cybergeo Conversation
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Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Faut-il institutionnaliser l’ECTQG?

open access: yes, 2017
Le 20e Colloque Européen de Géographie Théorique et Quantitative s’est tenu à York, du 7 au 11 septembre 2017. Organisé par nos collègues de l’université de Leeds, Michelle Morris, Mark Birkin et Nick Malleson, il a réuni environ 80 participants issus de
Cybergeo Conversation
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