Results 111 to 120 of about 1,961 (282)

Matching across Turns in Talk-in-Interaction: The Role of Prosody and Gesture [PDF]

open access: yes, 2012
Understanding the design of talk-in-interaction is important in many domains, including speech technology. Although phonetic, linguistic and gestural correlates have been identified for some of the social actions that conversational participants ...
Gorisch, Jan P.F.M.
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Modelling Speech Acts in Conversational Discourse [PDF]

open access: yes, 2005
Computational pragmatics and dialogue analysis is currently a rapid growing area of research in computational linguistics. Over the past five years or so, initiatives in modelling pragmatic aspects of dialogue have led to considerably improved spoken ...
Schiffrin, Amanda
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Uncommon ground: the distribution of dialogue contexts

open access: yes, 2009
PhDContext in dialogue is at once regarded as a set of resources enabling successful interpretation and is altered by such interpretations. A key problem for models of dialogue, then, is to specify how the shared context evolves.
Eshghi, Arash
core  

Clear and Engaging: A Review of Sidnell\u27s Conversation Analysis: An Introduction

open access: yes, 2011
Conversation Analysis: An Introduction by Jack Sidnell is a concise and clear primer to describing, analyzing, and understanding human talk. Combining theoretical descriptions and analysis of transcribed conversations, Sidnell (2010) explains the ...
Parylo, Oksana
core   +1 more source

Keeping the conversation open

open access: yesTheology in Scotland
The Second Vatican Council (1962–65) set out a new vision of the role of lay people in the Roman Catholic Church whereby they were no longer seen as passive recipients of clerical initiatives, but as active ministers of the Gospel. This article describes the historical context from which Vatican II emerged and outlines the scale and significance of the
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Factors Affecting Conversational Openings In English And Vietnamese

open access: yes, 2014
The Vietnamese often confront countless obstacles when communicating in English, especially in opening a conversation. In view of helping learners of English overcome these difficulties, this article aims at finding out similarities and differences in ...
My*, H. T. (Hoàng)
core  

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