Results 101 to 110 of about 1,961 (283)

Opening the conversation: An introduction to open educational resources

open access: yesJournal of New Librarianship, 2017
This column explores the concept of and issues surrounding Open Educational Resources (OER) for librarians.
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Pragmatics and the consequentiality of talk: a study of members' methods at a planning application meeting [PDF]

open access: yes, 1995
This study explores how talk is consequential by examining the sequential and pragmatic phenomena in talk-in-interaction. Reflecting the work of conversation analysis (CA), the approach assumes that the consequentiality of a 'context' must be ...
Glover, Kelly D., Glover, K.D
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Telephone conversation openings across languages, cultures and settings [PDF]

open access: yes, 2018
The organization of telephone conversation has received much scholarly attention since Schegloff’s pioneering work in the 1960s and 1970s (Schegloff 1968, 1979). There are several reasons why researchers have been fascinated by telephone conversations in
Márquez Reiter, Rosina   +1 more
core  

Towards debate and open conversation [PDF]

open access: yesScandinavian Economic History Review, 2016
Ojala, J., Reckendrees, A.
openaire   +3 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The social organisation of news interview interaction [PDF]

open access: yes
This thesis describes and analyses aspects of the social organisation of British news interview interaction. After a review of the sociological literature on the British news interview in Chapter 1, and a discussion of the evolution of news ...
Greatbatch, David
core  

The Effects of Video Recording on Office Workers' Conduct, and the Validity of Video Data for the Study of Naturally-Occurring Interactions

open access: yesForum: Qualitative Social Research, 2016
This article starts from the observation that social scientists using video to study naturally-occurring interactions are often questioned about the reliability of their data, by wider audiences, but also by scholars who raised concerns early on about ...
Sylvaine Tuncer
doaj  

Keeping the conversation open

open access: yesTheology in Scotland
The Second Vatican Council (1962–65) set out a new vision of the role of lay people in the Roman Catholic Church whereby they were no longer seen as passive recipients of clerical initiatives, but as active ministers of the Gospel. This article describes the historical context from which Vatican II emerged and outlines the scale and significance of the
openaire   +1 more source

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