Results 81 to 90 of about 1,961 (282)

Politeness in Ecuadorian Spanish

open access: yes, 1996
This paper examines politeness phenomena in Ecuadorian Spanish as reflected in the language of telephone conversations, and, as such, attempts to add another cultural perspective to the discussion of politeness issues and of Brown and Levinson's (1978 ...
Placencia, Maria Elena
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Natural conversation and efltextbook dialogues : a constrastive study [PDF]

open access: yes, 1991
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e ExpressãoExamina características estruturais, estratégicas e estilísticas de interações comerciais e conversações por telefone em inglês e português comparadas com ...
Dalacorte, Maria Cristina Faria
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Hermeneutic and ethnomethodological formulations of conversational and textual talk

open access: yes, 1982
This paper attempts to render explicit, and then present a critique of, certain affinities between hermeneutic and ethnomethodological work on conversation/discourse that are tentatively raised in Misgeld's (1977) discussion of Habermas and gadamer.
McHoul, A.W.
core  

Explanations and communicative constraints in naturally occurring discourse [PDF]

open access: yes, 1989
The subject matter of this thesis are some aspects of the expression of explanations in spoken discourse. The study of explanations has occupied the attention of many researchers in social psychology and in neighbouring disciplines; the study of talk ...
Rae, John Patrick, Rae, J.P
core  

Telephone conversation openings across languages, cultures and settings

open access: yes, 2010
The organization of telephone conversation has received much scholarly attention since Schegloff’s pioneering work in the 1960s and 1970s (Schegloff 1968, 1979). There are several reasons why researchers have been fascinated by telephone conversations in
Kang, Luke Kwong Kapathy   +5 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Openings and closings of telephone enquiries on hotel accomodation [PDF]

open access: yes, 2008
The aim of the study is to examine the openings and closings of telephone enquiries on hotel accommodation in Kuching city. The objectives of the study were : (i) to examine the structure of the opening and closing of telephone ...
Ngu,, Shing Yiing.
core  

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