Results 81 to 90 of about 1,961 (283)

Open Science: A Candid Conversation

open access: yesJournal of Advanced Academics, 2019
In response to concerns about the credibility of many published research findings, open science reforms such as preregistration, data sharing, and alternative forms of publication are being increasingly adopted across scientific communities. Although journals on giftedness and advanced academic research have already implemented several of these ...
Makel , Matthew, Smith , Kendal
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Uncommon ground: the distribution of dialogue contexts [PDF]

open access: yes, 2009
PhDContext in dialogue is at once regarded as a set of resources enabling successful interpretation and is altered by such interpretations. A key problem for models of dialogue, then, is to specify how the shared context evolves.
Eshghi, Arash
core  

Clear and Engaging: A Review of Sidnell\u27s Conversation Analysis: An Introduction [PDF]

open access: yes, 2011
Conversation Analysis: An Introduction by Jack Sidnell is a concise and clear primer to describing, analyzing, and understanding human talk. Combining theoretical descriptions and analysis of transcribed conversations, Sidnell (2010) explains the ...
Parylo, Oksana
core   +2 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Factors Affecting Conversational Openings In English And Vietnamese [PDF]

open access: yes, 2014
The Vietnamese often confront countless obstacles when communicating in English, especially in opening a conversation. In view of helping learners of English overcome these difficulties, this article aims at finding out similarities and differences in ...
My*, H. T. (Hoàng)
core  

Introduction: Opening the Conversation on Access [PDF]

open access: yesNew Chaucer Studies: Pedagogy and Profession
This issue opens with a reflection on the urgent theme of access in the humanities and continues with essays that address inequities, pedagogy, and global classrooms, alongside creative and experimental contributions that expand the possibilities of teaching medieval studies today.
Incifem Sari Tekin, Victoria Craggs
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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