Results 71 to 80 of about 1,961 (283)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Complaining and arguing in everyday conversation. [PDF]

open access: yes, 1998
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN021154 / BLDSC - British Library Document Supply CentreGBUnited ...
Dersley, Ian, Dersley, I.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

“Rush, I Love You”: Interactional Fandom on U.S. Political Talk Radio

open access: yesInternational Journal of Communication, 2013
This article analyzes the openings in host-caller interactions in three leading U.S. political talk radio (PTR) programs. Conversation analysis and membership categorization analysis are used to describe how fandom is achieved in these shows.
Gonen Dori-Hacohen
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Open Science: a Shift in the Conversation

open access: yes, 2019
Keynote talk at the Open Science Fair 2019, Porto, Portugal. Perhaps the most sincere and heart felt talk I have ever given about Open Science. I talk about things like research excellence, and how much damage has already done to science. I express the desire to shift the conversation towards topics like #failtales, mental health, reform of the ...
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Modelling dialogue: Challenges and Approaches [PDF]

open access: yes, 2005
Schlangen D. Modelling dialogue: Challenges and Approaches. Künstliche Intelligenz.
Schlangen, David ; https://orcid.org/
core   +1 more source

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