Results 251 to 260 of about 2,534,766 (303)

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Conversion Surgery Following Durvalumab Plus Tremelimumab in Unresectable Hepatocellular Carcinoma with Para-Aortic Lymph Node Metastases: A Case of Complete Hepatic Response and Lymphatic Resistance. [PDF]

Surg Case Rep
Uemura S, Tokumaru T, Tamura S, Tabuchi M, Sakamoto S, Yoshimatsu R, Matsumoto M, Iwata J, Okabayashi T.   +8 more
europepmc   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

The evolving concept of conversion surgery for upfront unresectable upper gastrointestinal and hepato-pancreato-biliary cancers: comprehensive review. [PDF]

BJS Open
Perri G, Engstrand J, Wright RD, Bronzwaer SFC, Kroese TE, Huang B, Acidi B, Vitale A, Tran Cao HS, van Hillegersberg R, Nilsson M, Sparrelid E, Katz MHG, Marchegiani G, Cillo U.   +14 more
europepmc   +1 more source

Induction therapy of pralsetinib followed by conversion surgery for unresectable locally advanced non-small cell lung cancer with the rearranged during transfection (RET) fusion gene mutation: protocol for a single-arm phase II prospective trial (the SALVAGE-P trial). [PDF]

J Thorac Dis
Deng HY, Qiu XM, Li L, Tang XJ, Zhou Q.
europepmc   +1 more source

Seven-year survival with no recurrence after conversion surgery for pancreatic ductal adenocarcinoma with peritoneal metastasis treated with intraperitoneal and intravenous chemotherapy: A case report. [PDF]

Mol Clin Oncol
Takahashi M, Matsumoto J, Suzuki Y, Oyamada Y, Tsuji Y, Hirano S.   +5 more
europepmc   +1 more source

Conversion Surgery via Laparoscopic Gastrectomy and Hepatectomy for Advanced Gastric Neuroendocrine Carcinoma with Extensive Liver Metastases: A Case Report. [PDF]

Surg Case Rep
Ishii S, Ehara K, Kawakami H, Nishie N.
europepmc   +1 more source

Outcomes of Conversion Surgery for Patients With Low-Risk Papillary Thyroid Carcinoma.

JAMA Otolaryngol Head Neck Surg
Levyn H, Scholfield DW, Eagan A, Boe LA, Shaha AR, Wong RJ, Shah JP, Ganly I, Morris LGT, Tuttle RM.   +9 more
europepmc   +1 more source

Conversion Surgery for Advanced Pancreatic Cancer [PDF]

Journal of Clinical Medicine, 2019
While primarily unresectable locally advanced pancreatic cancer (LAPC) used to be an indication for palliative therapy, a strategy of neoadjuvant therapy (NAT) and conversion surgery is being increasingly used after more effective chemotherapy regimens have become available for pancreatic ductal adenocarcinoma.
Oliver Strobel, Thomas Hank
exaly   +3 more sources

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Is Conversion a Complication of Laparoscopic Surgery?

Journal of Laparoendoscopic & Advanced Surgical Techniques, 2008
In this paper, we review our laparoscopic and thoracoscopic experience and look specifically at the cases that resulted in conversion.Data were retrieved on all minimally invasive surgical procedures performed in our institution.There were 1,759 cases performed between 1997 and 2007. Of these, 1,648 cases were laparoscopic and 111 thoracoscopic.
Boma T, Adikibi, Gordon A, MacKinlay, Fraser D, Munro, Claire, Clark   +3 more
openaire   +2 more sources