Results 41 to 50 of about 214,349 (248)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Energies, 2021 This paper introduces a new black-box approach for time domain modeling of commercially available single-phase photovoltaic (PV) inverters in low voltage networks.
Elias Kaufhold +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
EnergiesThis work contains the results of the research carried out on the framework of the design of the resonant power module of DAB. The peculiarity of this device is that it is supposed to be used as part of the basic element of a scalable power storage ...
Yuriy Yu. Perevalov +8 more
doaj +1 more source
Research and Application on New Generation of Traction IGBT Module Technology
机车电传动, 2021 The traction IGBT modules are the core power devices in the traction converters of modern railway locomotives for power convert and output. The new generation traction IGBT modules using the latest IGBT4, EC4 diode, VLD and DLC chips terminal edge ...
Mingyi CHEN +5 more
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
IET Renewable Power GenerationThis paper discusses the MPPT based on finite‐set model predictive control (FS‐MPC) in photovoltaic (PV) systems. Generally, the FS‐MPC implementation needs more sensors in comparison with the traditional methods due to the existence of the prediction ...
Mostafa Ahmed +5 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
cheminfo/biologic-converter: v0.6.0
, 2022 <a href="https://github.com/cheminfo/biologic-converter/compare/v0.5.0...v0.6.0">0.6.0</a> (2022-11-21) ⚠ BREAKING CHANGES <ul> <li>release refactored code</li> </ul> Features <ul> <li>release refactored ...
cheminfo-bot +4 more
core +1 more source