Results 81 to 90 of about 598,938 (299)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Boundary-mode operation of the boost converter for thermoelectric generator maximum power tracking [PDF]

open access: yes, 2014
This article has been made available through the Brunel Open Access Publishing Fund.Performance-favourable and noteworthy characteristics of the Boost converter are reported, when the latter operates in Maximum Power Tracking (MPT) mode, while fed from a
Theodoridis, M
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Optimization of DC - DC boost converter using fuzzy logic controller [PDF]

open access: yes, 2013
DC-DC converters are electronic devices used to change DC electrical power efficiently from one voltage level to another. Operation of the switching devices causes the inherently nonlinear characteristic of the DC-DC converters including one known as
Soluman Ahtiwish, Aimen Khalifa
core  

WIDE RANGE MODULATION INDEXES FEATURED CARRIER-BASED PWM STEPPED WAVEFORM FOR HALF-BRIDGE MODULAR MULTILEVEL CONVERTERS

open access: yesInternational Islamic University Malaysia Engineering Journal, 2018
: This paper presents simulation results of the influence of wide range modulation index values ( ) in carrier-based PWM strategy for application in generating the stepped waveform.
Majdee Tohtayong   +5 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Fast-response frequency-to-analog converter [PDF]

open access: yes, 1967
Frequency-to-analog converter has a fast response time and a low ripple. The circuit uses a frequency-to-pulse converter which provides two pulse trains, both at the same frequency as that of the input signal, but with a 10 microsecond difference between
Hagihara, F. S.
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Development of a Protocol Converter from SMA Data to Modbus TCP for SCADA Integration

open access: yesRevista Tecnológica
The integration of distributed energy resources into smart microgrids frequently necessitates seamless communication between heterogeneous devices and centralized supervisory systems.
Santiago Ismael Araujo Ochoa   +3 more
doaj   +1 more source

Simple Wide Frequency Range Impedance Meter Based on AD5933 Integrated Circuit

open access: yesMetrology and Measurement Systems, 2015
As it contains elements of complete digital impedance meter, the AD5933 integrated circuit is an interesting solution for impedance measurements. However, its use for measurements in a wide range of impedances and frequencies requires an additional ...
Chabowski Konrad   +3 more
doaj   +1 more source

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