Results 81 to 90 of about 249,873 (283)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Requirements for Power Converters [PDF]
, 2016 This paper introduces the requirements for power converters needed for particle accelerators. It describes the role of power converters and the challenges and constraints when powering magnets.
Burnet, J. -P.
core +3 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Optimal Dynamic Analysis of Electrical/Electronic Components in Wind Turbines
Energies, 2017 Electrical and electronic components are very important subcomponents in modern industrial wind turbines. Complex multimegawatt wind turbines are continuously being installed both onshore and offshore, continuously increasing the demand for sophisticated
Fausto Pedro García Márquez +4 more
doaj +1 more source
Adder Based Residue to Binary Number Converters for (2n - 1; 2n; 2n + 1) [PDF]
, 2002 Copyright © 2002 IEEEBased on an algorithm derived from the new Chinese remainder theorem I, we present three new residue-to-binary converters for the residue number system (2n-1, 2n, 2n+1) designed using 2n-bit or n-bit adders with improvements on speed,
Aboulhamid, M. +3 more
core +2 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
SensorsMajor depressive disorder requires scalable, low-burden screening tools. We examined whether three-channel resting-state EEG can support reliable discrimination between major depressive disorder and healthy controls using a lightweight model compatible ...
Oana-Isabela Știrbu +4 more
doaj +1 more source
Evolution of the SPS Power Converter Controls towards the LHC Era [PDF]
, 2001 By the end of the nineties, the power converter control system (Mugef) of the CERN proton accelerator (SPS) had undergone a complete modernization.
Brazier, J. C. L. +2 more
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Computational Analysis of EEG Responses to Anxiogenic Stimuli Using Machine Learning Algorithms
Applied SciencesAnxiety disorders are commonly assessed using instruments such as HAM-A and GAD-7. These tools rely on patient self-report and clinician interpretation, which may introduce variability.
Felix-Constantin Adochiei +5 more
doaj +1 more source