Results 31 to 40 of about 28,771 (260)

Direct and Hierarchical Models for Aggregating Spatially Dependent Catastrophe Risks

Risks, 2019
We present several fast algorithms for computing the distribution of a sum of spatially dependent, discrete random variables to aggregate catastrophe risk. The algorithms are based on direct and hierarchical copula trees.
Rafał Wójcik, Charlie Wusuo Liu, Jayanta Guin   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The multiple interpolation de la Vallée Poussin problem

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2015
This article is concerned with the solving of multiple interpolation de La Vallée Poussin problem for generalized convolution operator. Particular ate tention is paid to the proving of the sequential sufficiency of the set of solutions of the generalized
Valentin V Napalkov, Aigul U Mullabaeva
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

On a shifted convolution sum problem

Journal of Number Theory, 2022
It is proved here that for a holomorphic newform of prime level \( p \) and trivial nebentypus, the shifted convolution sum \(\sum_{m=1}^{\infty } \lambda_f(m)\lambda_f(m+pu)F(m/M) \) is \( \ll p^{1/2+ \varepsilon} M^{3/4}\) for \( p^{1+\varepsilon}\ll M\ll p^{3-\varepsilon} \) and ...
openaire   +2 more sources

Notes on the Free Additive Convolution

Axioms
The investigation of free additive convolution is a key concept in free probability theory, offering a framework for studying the sum of freely independent random variables.
Shokrya S. Alshqaq, Raouf Fakhfakh, Fatimah Alshahrani   +2 more
doaj   +1 more source

Efficient construction of match strength distributions for uncertain multi-locus genotypes

Heliyon, 2018
Natural variation in biological evidence leads to uncertain genotypes. Forensic comparison of a probabilistic genotype with a person's reference gives a numerical strength of DNA association. The distribution of match strength for all possible references
Mark W. Perlin
doaj   +1 more source

MATRIKS ATAS RING DERET PANGKAT TERGENERALISASI MIRING

Barekeng, 2021
Let R be a ring with unit elements,  strictly ordered monoids, and  a monoid homomorphism. Formed , which is a set of all functions from S to R with  are Artin and narrow.
Siti Rugayah, Ahmad Faisol, Fitriani Fitriani   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Initial Problem for Two-Dimensional Hyperbolic Equation with a Nonlocal Term

Mathematics, 2022
In this paper, we study the Cauchy problem in a strip for a two-dimensional hyperbolic equation containing the sum of a differential operator and a shift operator acting on a spatial variable that varies over the real axis. An operating scheme is used to
Vladimir Vasilyev, Natalya Zaitseva
doaj   +1 more source