Results 31 to 40 of about 28,962 (257)

The multiple interpolation de la Vallée Poussin problem

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2015
This article is concerned with the solving of multiple interpolation de La Vallée Poussin problem for generalized convolution operator. Particular ate tention is paid to the proving of the sequential sufficiency of the set of solutions of the generalized
Valentin V Napalkov, Aigul U Mullabaeva
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Binomial convolution sum of divisor functions associated with Dirichlet character modulo 8

open access: yesOpen Mathematics
In this article, we compute binomial convolution sums of divisor functions associated with the Dirichlet character modulo 8, which is the remaining primitive Dirichlet character modulo powers of 2 yet to be considered.
Jin Seokho, Park Ho
doaj   +1 more source

Notes on the Free Additive Convolution

open access: yesAxioms
The investigation of free additive convolution is a key concept in free probability theory, offering a framework for studying the sum of freely independent random variables.
Shokrya S. Alshqaq   +2 more
doaj   +1 more source

Efficient construction of match strength distributions for uncertain multi-locus genotypes

open access: yesHeliyon, 2018
Natural variation in biological evidence leads to uncertain genotypes. Forensic comparison of a probabilistic genotype with a person's reference gives a numerical strength of DNA association. The distribution of match strength for all possible references
Mark W. Perlin
doaj   +1 more source

On a shifted convolution sum problem

open access: yesJournal of Number Theory, 2022
It is proved here that for a holomorphic newform of prime level \( p \) and trivial nebentypus, the shifted convolution sum \(\sum_{m=1}^{\infty } \lambda_f(m)\lambda_f(m+pu)F(m/M) \) is \( \ll p^{1/2+ \varepsilon} M^{3/4}\) for \( p^{1+\varepsilon}\ll M\ll p^{3-\varepsilon} \) and ...
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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