Results 51 to 60 of about 28,962 (257)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Evaluation of two convolution sums involving the sum of divisors function [PDF]

open access: yesBulletin of the Australian Mathematical Society, 2006
The convolution sumsandare evaluated for alln∈ ℕ.
Lemire, Mathieu, Williams, Kenneth S.
openaire   +2 more sources

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Convolution Sums of Some Functions on Divisors

open access: yesRocky Mountain Journal of Mathematics, 2007
This is an old paper uploaded for archival ...
openaire   +4 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Bernoulli Polynomials and Convolution Sums [PDF]

open access: yesBritish Journal of Mathematics & Computer Science, 2014
In this paper, we study the summations ∑ (a,b,c)∈N a+b+c=n (f(a+ b) + f(b+ c) + f(c+ a)) and ∑ (a,b,c,d)∈N a+b+c+d=n (f(a+ b+ c) + f(b+ c+ d) + f(c+ d+ a)). Especially, for the first summation we obtain some relations related to Bernoulli and Euler polynomials.
openaire   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

Double Weight-Based SAR and Infrared Sensor Fusion for Automatic Ground Target Recognition with Deep Learning

open access: yesRemote Sensing, 2018
This paper presents a novel double weight-based synthetic aperture radar (SAR) and infrared (IR) sensor fusion method (DW-SIF) for automatic ground target recognition (ATR).
Sungho Kim, Woo-Jin Song, So-Hyun Kim
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

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