Proton-pump inhibitor use is associated with a broad spectrum of neurological adverse events including impaired hearing, vision, and memory. [PDF]
, 2019 Proton-pump inhibitors, PPIs, are considered effective therapy for stomach acid suppression due to their irreversible inhibition of the hydrogen/potassium pump in the gastric parietal cells. They are widely prescribed and are considered safe for over-the-
Abagyan, Ruben +4 more
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Acta Neurobiologiae Experimentalis, 2010 This study aimed to examine whether celecoxib influences clonic seizure thresholds through modulation of nitric oxidergic (NO) pathway. The effect of celecoxib (1-5 mg per kg, p.o.) was investigated on clonic seizures induced by pentylenetetrazole (PTZ ...
A. Zandieh +5 more
semanticscholar +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Isolated Inferior Sagittal Sinus Thrombosis in Young Patient: Rare Case Report
International Medical Case Reports Journal, 2023 Mohamed Sheikh Hassan,1,2 Abdiwahid Ahmed Ibrahim,1 Engin Nakus,1 Bakar Ali Adam,1 Nor Osman Sidow,1 Mohamed Farah Osman Hidig,1 Said Abdi Mohamed,1 Abdulkadir Ahmed Mohamed,1 Abdulkamil Abdullahi Adani,3 Yahye Garad Mohamed,4 Ismail Gedi Ibrahim,4 Said ...
Sheikh Hassan M +11 more
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Comparison between rectal administration of diazepam in solution and intravenous administration for management of convulsive disorders in infants and children [PDF]
Journal of Kerman University of Medical Sciences, 1997 In order to compare rectal and intravenous(IV) administration of diazepam for management of convulsions,a prospective cross-sectional case-control study was conducted on 94 convulsive infants and children referring to the Emergency department of the ...
P Niknafs, A Ahmadi, JH Saraf zadeh
doaj
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The effect of epilepsy on pregnancy outcomes
Van Tıp Dergisi, 2018 INTRODUCTION: Approximately 25% of epilepsy cases are in reproductive ages, their seizures are kept under control by the current anti-epileptic drugs, and pregnancy rates are higher in these cases.
Numan Çim +9 more
doaj +1 more source
Evaluation of Febrile Convulsion; prevalence & clinical manifestations among children under 6 years referring to south Health Centers in Tehran on 2008 [PDF]
Objective: The present study was designed to evaluate the frequency & clinical manifestations of the Febrile Convulsion in children under 6 years in an Iranian sample.
آهنگرزاده, سميه +2 more
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Automatism is never a defence [PDF]
, 2014 The central aim of this article is to set out and justify the contention that automatism is never a defence, not even exceptionally. Where D is not at fault for her lack of voluntariness, the term ‘automatism’ is simply a shorthand explanation that D ...
Child, John, Reed, Alan
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