This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo +11 more
wiley +1 more source
Metabolism of soluble sugars in 4 varieties of banana, and activity of associated enzymes [PDF]
Changes in amounts of sucrose, hexoses (glucose and fructose), and in activities of Sucrose-phosphate synthase (SPS), Sucrose synthase (SuSy) (sucrose hydrolytic way), Neutral Invertase (NIV) and Acid Invertase (AIV) were studied during development and ...
Chillet, Marc +5 more
core
CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma +12 more
wiley +1 more source
Organic Thin‐Film Transistors for Neuromorphic Computing
Organic thin‐film transistors (OTFTs) are reviewed for neuromorphic computing applications, highlighting their power‐efficient, and biological time‐scale operation. This article surveys OFET and OECT devices, compares them with memristors and CMOS, analyzes how fabrication parameters shape spike‐based metrics, proposes standardized characterization ...
Luke McCarthy +2 more
wiley +1 more source
White spot syndrome virus (WSSV) transmission risk through infected cooked shrimp products assessed by polymerase chain reaction (PCR) and bio-inoculation studies [PDF]
The aim of the study was to evaluate the resistance of white spot syndrome virus (WSSV) in shrimps (Penaeus monodon) to the process of cooking. The cooking was carried out at 1000C six different durations 5, 10, 15, 20, 25 and 30 min.
Devivaraprasad Reddy, A.A. +2 more
core
Self‐Adhesive Conductive Elastomers for Gel‐Free Biopotential Recording
σPOMaC, a self‐adhesive conductive citrate elastomer incorporating PEDOT:PSS and DBSA, enables gel‐free biopotential electrodes with stable conductivity and intrinsic skin adhesion. The composite exhibits low resistivity (∼ 0.02 Ω·cm), robust electrical performance during repeated use, and reliable on‐body ECG acquisition comparable to Ag/AgCl ...
Kirstie M. K. Queener +7 more
wiley +1 more source
Roadmap for High‐Throughput Ceramic Materials Synthesis and Discovery for Batteries
This work examines ceramic synthesis through the lens of high‐throughput synthesis and optimization, identifying opportunities for faster, adaptable routes. It emphasizes flexible liquid precursor–to–solid film methods over slower solid‐state approaches and highlights computer‐aided decision making to optimize both material properties and device ...
Jesse J. Hinricher +10 more
wiley +1 more source
Prelimenary results on a comparative study evaluating landraces of common bean (Phaseolus vulgaris L.) in organic agriculture in a protected area (Northern Greece) [PDF]
Organic farming requires cultivars or landraces that are specifically adapted to this low input cropping system. Six landraces of Greek common dry bean (Phaseolus vulgaris L.) and one from the neighbouring Former Yugoslav Republic of Macedonia (FYROM ...
Eustathios, Dr. Tamoutsidis +3 more
core
Emerging Materials and Future Strategies for Solid Oxide Electrochemical Cells
Solid oxide electrochemical cells operate under strongly coupled electrochemical and thermodynamic conditions, where performance is constrained by interactions among crystal structure, defect chemistry, and interfacial evolution. This review, based on a structure‐defect‐property‐durability framework, reveals the roles of lattice symmetry and defect ...
Qiuchun Lu +4 more
wiley +1 more source
Beyond the Ban—Shedding Light on Smallholders' Price Vulnerability in Indonesia's Palm Oil Industry
ABSTRACT The Indonesian government imposed a palm oil export ban in April 2022 to address rising cooking oil prices. This study explores oil palm smallholders' vulnerability to the policy using descriptive statistics, Lasso, and post‐Lasso OLS regressions.
Charlotte‐Elena Reich +3 more
wiley +1 more source

