Results 41 to 50 of about 324,471 (291)

Numerical Investigation of the Effects of Lattice Array Structures on Film Cooling Performance

open access: yesEnergies, 2022
To better understand the mechanism influencing the periodic lattice structures in gas turbine blade cooling, these numerical simulations present a systematic comparison of the effects in cases involving pin-fin, Kagome, and BCC lattice arrays on film ...
Qiang Fu   +3 more
doaj   +1 more source

Advances and challenges in commercializing radiative cooling [PDF]

open access: yes, 2019
Radiative cooling (RC) dissipates terrestrial heat to outer space through the atmospheric window, without external energy input and production of environmental pollutants. More and more efforts have been devoted to this clean promising cooling technology;
Feng, W   +4 more
core  

Dynamical cooling of galactic discs by molecular cloud collisions -- Origin of giant clumps in gas-rich galaxy discs

open access: yes, 2017
Different from Milky-Way-like galaxies, discs of gas-rich galaxies are clumpy. It is believed that the clumps form because of gravitational instability.
Li, Guang-Xing
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Review of Film Cooling Techniques for Aerospace Vehicles

open access: yesEnergies
Film cooling, a vital method for controlling surface temperatures in components subjected to intense heat, strives to enhance efficiency through innovative technological advancements.
Edidiong Michael Umana, Xiufeng Yang
doaj   +1 more source

Numerical Computation and Optimization of Turbine Blade Film Cooling

open access: yesAdvances in Mechanical Engineering, 2014
The effect of film cooling parameters on the cooling effectiveness of an actual turbine blade is studied numerically. Film cooling parameters such as the hole shape, holes distribution, blowing ratio, streamwise angle, and spanwise angle are investigated
Ahmed M. Elsayed   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Cooling Performance of Impingement–Effusion Double-Wall Configurations Under Atmospheric and Elevated Pressures

open access: yesApplied Sciences
The combustor liner of the modern aero-engine operates under extreme thermal loads with limited coolant supply, necessarily making efficient cooling approaches important.
Rongxing Zhang   +7 more
doaj   +1 more source

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