Results 51 to 60 of about 325,229 (311)

Cooling Performance of Impingement–Effusion Double-Wall Configurations Under Atmospheric and Elevated Pressures

Applied Sciences
The combustor liner of the modern aero-engine operates under extreme thermal loads with limited coolant supply, necessarily making efficient cooling approaches important.
Rongxing Zhang, Wei Li, Jianbai Jiang, Xudong Lang, Jinxin Dai, Tianyou Lian, Xiaoxiang Shi, Wei Li   +7 more
doaj   +1 more source

Effectiveness of hand cooling and a cooling jacket on post‐exercise cooling rates in hyperthermic athletes [PDF]

European Journal of Sport Science, 2018
AbstractThis study compared the effects of a hand cooling glove (∼16°C water temperature; subatmospheric pressure of −40 mmHg) and a cooling jacket (CJ) on post‐exercise cooling rates (gastrointestinal core temperature, Tc; skin temperature, Tsk) and cognitive performance (the Stroop Colour–Word test). Twelve male athletes performed four trials (within
Tessa Maroni, Brian Dawson, Kimberley Barnett, Kym Guelfi, Carly Brade, Louise Naylor, Chris Brydges, Karen Wallman   +7 more
openaire   +3 more sources

Turbulent mixing film cooling correlation [PDF]

, 1972
Film cooling effectiveness correlation predicts air flow requirement for cooling gas turbine combustors. Turbulent mixing model accounts for mixing rate between cooling film and hot gas stream.
Juhasz, A. J., Marek, C. J.
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Experimental Investigation on the Effects of DBD Plasma on the Film Cooling Effectiveness of a 30-Degree Slot

Applied Sciences, 2017
The effects of dielectric barrier discharge (DBD) plasma on the film cooling effectiveness of a 30-degree slot was experimentally investigated in a low-speed wind tunnel.
Ye Jee Kim, Gi Mun Kim, Youhwan Shin, Jae Su Kwak   +3 more
doaj   +1 more source

Simulation and experimental study of double holes film cooling [PDF]

, 2012
In the modern gas turbine, film cooling has been widely used to provide thermal protection for the external surface of the gas turbine blades. Numerous number of geometrical arrangement film cooling have been presented for the past 50 years.
Abdul Rahim, Erween, Abdul Rahman, Norzaina, Mustapa, Mohammad Sukri, Wahab, Md Saidin   +3 more
core   +4 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Efficiency of quantum controlled non-Markovian thermalization [PDF]

, 2015
We study optimal control strategies to optimize the relaxation rate towards the fixed point of a quantum system in the presence of a non-Markovian dissipative bath.
Calarco, Tommaso, Fazio, Rosario, Giovannetti, Vittorio, Huelga, Susana F., Montangero, Simone, Mukherjee, Victor   +5 more
core   +3 more sources