Results 131 to 140 of about 128,402 (265)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Synthesis, Structures, and Solution Studies of a New Class of [Mo₂O₂S₂]-Based Thiosemicarbazone Coordination Complexes. [PDF]

ACS Omega, 2022
Fuior A, Cebotari D, Haouas M, Marrot J, Espallargas GM, Guérineau V, Touboul D, Rusnac RV, Gulea A, Floquet S.   +9 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Co(II), Cu(II), and Ni(II) Coordination Complexes: Synthesis, Characterization, Experimental, and Computational Study on Potential Antiplasmodial Activity. [PDF]

ChemMedChem
Ezenarro-Salcedo D, Fonseca-López D, Patiño-Cubides A, Velasco-Pareja MC, Yasnot-Acosta MF, Serrano-Sterling C, Rodríguez A, Macías MA, Orjuela AL, Valderrama-Aguirre A, Hurtado JJ.   +10 more
europepmc   +1 more source

In situ beam reduction of Pu(IV) and Bk(IV) as a route to trivalent transuranic coordination complexes with hydroxypyridinone chelators. [PDF]

J Synchrotron Radiat, 2022
Carter KP, Wacker JN, Smith KF, Deblonde GJP, Moreau LM, Rees JA, Booth CH, Abergel RJ.   +7 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Laser-Patternable and Stretchable Metal Electrodes Using Metal-Amine Coordination Complexes. [PDF]

Adv Mater
Lee S, Ho NT, Kim JH, Kang G, Ko H.
europepmc   +1 more source

Ferric Pyrophosphate Forms Soluble Iron Coordination Complexes with Zinc Compounds and Solubilizing Agents in Extruded Rice and Predicts Increased Iron Solubility and Bioavailability in Young Women. [PDF]

J Nutr, 2023
Scheuchzer P, Syryamina VN, Zimmermann MB, Zeder C, Nyström L, Yulikov M, Moretti D.   +6 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Advances in the Exploration of Coordination Complexes of Vanadium in the Realm of Alzheimer's Disease: A Mini Review. [PDF]

Molecules
Cruz-Navarro JA, Delgado-Rangel LH, Malpica-Calderón R, Sánchez-Mora AT, Ponce-Bolaños H, González-Oñate AF, Alí-Torres J, Colorado-Peralta R, Canseco-Gonzalez D, Reyes-Márquez V, Morales-Morales D.   +10 more
europepmc   +1 more source