Results 171 to 180 of about 12,187 (208)

Retromer protein VPS29 plays a crucial and positive role in the sumoylation system mediated by E3 SUMO ligase SIZ1. [PDF]

open access: yesPlant J
Min WK   +11 more
europepmc   +1 more source

Cryptochrome 1 promotes photomorphogenesis in Arabidopsis by displacing substrates from the COP1 ubiquitin ligase. [PDF]

open access: yesPlant J
Trimborn L   +8 more
europepmc   +1 more source

Conservation and divergence of UVR8-COP1/SPA-HY5 signaling in UV-B responses of Marchantia polymorpha

open access: yes
Liang Y   +10 more
europepmc   +1 more source

Promotion of photomorphogenesis by COP1

Plant Molecular Biology, 2004
CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) represses photomorphogenesis in darkness by targeting nuclear-localized transcription factors to proteasome-mediated degradation. Upon light exposure, COP1 migrates to the cytosol allowing photomorphogenesis to proceed but the residual nuclear pool down-regulates light signaling mediated by phytochrome A.
Hernán E, Boccalandro   +4 more
openaire   +2 more sources

Dissecting the functions of COP1 in the UVR8 pathway with a COP1 variant in Arabidopsis

The Plant Journal, 2022
SUMMARYCOP1 is a critical repressor of plant photomorphogenesis in darkness. However, COP1 plays distinct roles in the photoreceptor UVR8 pathway in Arabidopsis thaliana. COP1 interacts with ultraviolet B (UV‐B)‐activated UVR8 monomers and promotes their retention and accumulation in the nucleus.
Qianwen Zhang   +6 more
openaire   +2 more sources

Spotlight on the role of COP1 in tumorigenesis

Nature Reviews Cancer, 2012
COP1 is an E3 ubiquitin ligase that is involved in the ubiquitylation of various protein substrates to trigger their proteasomal degradation. Although originally identified in a light signalling pathway in plants, biochemical studies have identified putative targets of mammalian COP1 with relevant roles in tumorigenesis, including the oncoproteins JUN ...
Jean-Christophe Marine
exaly   +3 more sources

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