"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? [PDF]
Some pathogens utilize unique routes to enter cells that may evade the intracellular barriers encountered by the typical clathrin-mediated endocytic pathway.
Medina-Kauwe, LK
core +1 more source
New COP1-binding motifs involved in ER retrieval [PDF]
Coatomer-mediated sorting of proteins is based on the physical interaction between coatomer (COP1) and targeting motifs found in the cytoplasmic domains of membrane proteins. For example, binding of COP1 to dilysine (KKXX) motifs induces specific retrieval of tagged proteins from the Golgi back to the endoplasmic reticulum (ER).
Cosson, P. +3 more
openaire +3 more sources
Rapid reversion from monomer to dimer regenerates the ultraviolet-B photoreceptor UV RESISTANCE LOCUS8 in intact arabidopsis plants [PDF]
Arabidopsis (Arabidopsis thaliana) UV RESISTANCE LOCUS8 (UVR8) is a photoreceptor that specifically mediates photomorphogenic responses to ultraviolet (UV)-B in plants.
Heilmann, M., Jenkins, G.I.
core +1 more source
Ethylene promotes hypocotyl growth and HY5 degradation by enhancing the movement of COP1 to the nucleus in the light. [PDF]
In the dark, etiolated seedlings display a long hypocotyl, the growth of which is rapidly inhibited when the seedlings are exposed to light. In contrast, the phytohormone ethylene prevents hypocotyl elongation in the dark but enhances its growth in the ...
Yanwen Yu +7 more
doaj +1 more source
An analysis of supply chain related graduate programmes in Europe [PDF]
This is the post-print version of the Article. The official published version of the Article can be accessed from the links below. Copyright @ 2013 Emerald Group Publishing Limited.Purpose – Motivated by a lack of studies in graduate level supply chain ...
Des Doran +4 more
core +1 more source
COP1 and GSK3β Cooperate to Promote c-Jun Degradation and Inhibit Breast Cancer Cell Tumorigenesis
High abundance of c-Jun is detected in invasive breast cancer cells and aggressive breast tumor malignancies. Here, we demonstrate that a major cause of high c-Jun abundance in invasive breast cancer cells is prolonged c-Jun protein stability owing to ...
Jing Shao +12 more
doaj +1 more source
The COP9 SIGNALOSOME is required for postembryonic meristem maintenance in Arabidopsis thaliana [PDF]
Cullin-RING E3 ligases (CRLs) regulate different aspects of plant development, and are activated by modification of their cullin subunit with the ubiquitin-like protein NEDD8 (NEural precursor cell expressed Developmentally Down-regulated 8) (neddylation)
Boccaccini, Alessandra +10 more
core +1 more source
COP1 regulates the stability of CAM7 to promote photomorphogenic growth
The unique member of the calmodulin gene family, Calmodulin7 (CAM7), plays a crucial role as transcriptional regulator to promote Arabidopsis seedling development.
Dhirodatta Senapati +6 more
doaj +1 more source
A photo-responsive F-box protein FOF2 regulates floral initiation by promoting FLC expression in Arabidopsis. [PDF]
Floral initiation is regulated by various genetic pathways in response to light, temperature, hormones and developmental status; however, the molecular mechanisms underlying the interactions between different genetic pathways are not fully understood ...
He, Reqing +16 more
core +1 more source
Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao +8 more
wiley +1 more source

