Results 31 to 40 of about 602,916 (384)
Objective measurement of cough frequency during COPD exacerbation convalescence [PDF]
, 2015 Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Cough and sputum production are associated with adverse outcomes in COPD and are common during COPD exacerbation (AE-COPD).
Crooks, Michael G. +5 more
core +1 more source
Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis
Nature Communications, 2019 Ferroptosis is a necrotic form of regulated cell death (RCD) mediated by phospholipid peroxidation in association with free iron-mediated Fenton reactions.
Masahiro Yoshida +26 more
semanticscholar +1 more source
Nature Communications, 2017 Bcl-2 interacting killer (Bik) decreases airway epithelial hyperplasia via apoptosis mediated by calcium release from the endoplasmic reticulum (ER), but the mechanism is unclear. Here the authors show that Bik promotes Bak enrichment at the ER to tether
Yohannes A. Mebratu +6 more
doaj +1 more source
Pulmonary artery stiffness in chronic obstructive pulmonary disease (copd) and emphysema: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study [PDF]
, 2018 Purpose: Chronic obstructive pulmonary disease (COPD) and particularly emphysema are characterized by stiffness of the aorta, due in part to accelerated elastin degradation in the lungs and aorta. Stiffness of the pulmonary arteries (PAs) may also be
Balte, Pallavi +12 more
core +1 more source
Impact of COPD and anemia on motor and cognitive performance in the general older population: results from the English longitudinal study of ageing [PDF]
, 2020 Background: Cognitive and motor-performance decline with age and the process is accelerated by decline in general health. In this study, we aimed to estimate the effects of COPD and HB levels on cognitive and motor performance in the general older ...
Grittner, Ulrike +5 more
core +2 more sources
European Respiratory Review, 2015 Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence ...
Bartolome R. Celli +53 more
doaj +1 more source
BMC Pulmonary Medicine, 2022 Background Asthma patients with obesity often have a high disease burden, despite the use of high-dose inhaled corticosteroids (ICS). In contrast to asthmatics with normal weight, the efficacy of ICS in patients with obesity and asthma is often ...
Jan A. Witte +6 more
doaj +1 more source
Multidisciplinary Respiratory Medicine, 2010 The paper by Inal-Ince and colleagues (pag. 162-167) examines fatigue in chronic obstructive pulmonary disease (COPD) relating it to multi dimensional in- dices of overall disease severity, BODE and SAFE. It is the selection of these indices that will be examined in this Editorial.
openaire +4 more sources
Asthma Symptoms Do not Predict Spirometry
Canadian Respiratory Journal, 2007 BACKGROUND: Asthma is a disease characterized by variable airflow obstruction, but the measurement of airflow is often omitted in the process of diagnosis and management of the disease.
Robert L Cowie +2 more
doaj +1 more source
Testing for alpha-1 antitrypsin in COPD in outpatient respiratory clinics in Spain: A multilevel, cross-sectional analysis of the EPOCONSUL study [PDF]
, 2018 Background Alpha-1 antitrypsin deficiency (AATD) is the most common hereditary disorder in adults, but is under-recognized. In Spain, the number of patients diagnosed with AATD is much lower than expected according to epidemiologic studies.
Alcázar Navarrete, Bernardino +6 more
core +1 more source