Results 31 to 40 of about 404,062 (356)
Asthma Symptoms Do not Predict Spirometry
BACKGROUND: Asthma is a disease characterized by variable airflow obstruction, but the measurement of airflow is often omitted in the process of diagnosis and management of the disease.
Robert L Cowie +2 more
doaj +1 more source
Novel pharmacotherapies introduce additional options to providers and patients in how to best treat chronic obstructive pulmonary disease (COPD). Emerging data question the role of inhaled corticosteroids in COPD treatment, particularly as combination ...
Sharon R Rosenberg, Ravi Kalhan
doaj +1 more source
Chronic obstructive pulmonary disease (COPD) is responsible for early mortality, high death rates and significant cost to health systems. The projection for 2020 indicates that COPD will be the third leading cause of death worldwide (from sixth in 1990) and fifth leading cause of years lost through early mortality or handicap (disability-adjusted life ...
P. O. Girodet, Chantal Raherison
openaire +4 more sources
Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF
The unfolded protein response (UPR) is a direct consequence of cellular endoplasmic reticulum (ER) stress and a key disease driving mechanism in IPF.
Susan Monkley +16 more
doaj +1 more source
BACKGROUND: The value of other health care professionals is increasingly being recognized to compensate for the shortage of physicians in Canada. Chronic cough is one of the most common reasons for consultation with a respirologist. In the present study,
Stephen K Field +4 more
doaj +1 more source
Eosinophilic inflammation in COPD: from an inflammatory marker to a treatable trait
The heterogeneity of chronic obstructive pulmonary disease (COPD) creates many diagnostic, prognostic, treatment and management challenges, as the pathogenesis of COPD is highly complex and the underlying cellular and molecular mechanisms remain poorly ...
B. David +3 more
semanticscholar +1 more source
Airway inflammation in COPD: progress to precision medicine
Chronic obstructive pulmonary disease (COPD) is a significant cause of morbidity and mortality worldwide, and its prevalence is increasing. Airway inflammation is a consistent feature of COPD and is implicated in the pathogenesis and progression of COPD,
C. Brightling, Neil J Greening
semanticscholar +1 more source
This review article summarizes the main treatments for chronic obstructive pulmonary disease, their mechanisms, and the key evidence from trials supporting their use. Drug classes covered were short acting beta agonists (SABA), short acting muscarinic antagonists (SAMA), long acting beta agonists (LABA), long acting antimuscarinics (LAMA), inhaled ...
Stan Ejiofor +2 more
openaire +5 more sources
Global and regional estimates of COPD prevalence: Systematic review and meta–analysis
Background The burden of chronic obstructive pulmonary disease (COPD) across many world regions is high. We aim to estimate COPD prevalence and number of disease cases for the years 1990 and 2010 across world regions based on the best available evidence ...
D. Adeloye +12 more
semanticscholar +1 more source
Telemedicine in COPD: An Overview by Topics
COPD is a major cause of morbidity and mortality worldwide and carries a huge and growing economic and social burden. Telemedicine might allow the care of patients with limited access to health services and improve their self-management. During the COVID-
M. Barbosa +4 more
semanticscholar +1 more source

