Results 31 to 40 of about 453,081 (334)
Asthma Symptoms Do not Predict Spirometry
Canadian Respiratory Journal, 2007 BACKGROUND: Asthma is a disease characterized by variable airflow obstruction, but the measurement of airflow is often omitted in the process of diagnosis and management of the disease.
Robert L Cowie +2 more
doaj +1 more source
COPD and cardiovascular disease [PDF]
, 2019 COPD is one of the major public health problems in people aged 40 years or above. It is currently the 4th leading cause of death in the world and projected to be the 3rd leading cause of death by 2020.
André, S. +5 more
core +3 more sources
Does the BCL-2 family member BIK control lung carcinogenesis?
Molecular & Cellular Oncology, 2018 Hyperplastic airway epithelial cells may be the cause for increased risk for lung cancer in patients with chronic lung diseases. The B-cell lymphoma 2 (Bcl-2) family member, Bcl-2-interacting killer (BIK), triggers cell death specifically in these ...
Yohannes A. Mebratu, Yohannes Tesfaigzi
doaj +1 more source
Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease [PDF]
, 2016 Background: Cigarette smoke induced oxidative stress has been shown to reduce silent information regulator 1 (Sirt1) levels in lung tissue from smokers and patients with COPD patients.
Akai, Masaya +11 more
core +2 more sources
Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF
Scientific Reports, 2021 The unfolded protein response (UPR) is a direct consequence of cellular endoplasmic reticulum (ER) stress and a key disease driving mechanism in IPF.
Susan Monkley +16 more
doaj +1 more source
Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population [PDF]
, 2019 Various phenotypes exist in asthma and Chronic Obstructive Pulmonary Disease (COPD). These are important to identify in order to guide treatment decisions.
Brusselle, Guy +4 more
core +1 more source
F1000Research, 2017 Novel pharmacotherapies introduce additional options to providers and patients in how to best treat chronic obstructive pulmonary disease (COPD). Emerging data question the role of inhaled corticosteroids in COPD treatment, particularly as combination ...
Sharon R Rosenberg, Ravi Kalhan
doaj +1 more source
European Respiratory Review, 2009 Chronic obstructive pulmonary disease (COPD) is responsible for early mortality, high death rates and significant cost to health systems. The projection for 2020 indicates that COPD will be the third leading cause of death worldwide (from sixth in 1990) and fifth leading cause of years lost through early mortality or handicap (disability-adjusted life ...
P. O. Girodet, Chantal Raherison
openaire +4 more sources
Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol. [PDF]
, 2015 Medication adherence among patients with chronic diseases, such as COPD, may be suboptimal, and many factors contribute to this poor adherence. One major factor is the frequency of medication dosing.
Albertson, Timothy E +3 more
core +1 more source
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2013 This review article summarizes the main treatments for chronic obstructive pulmonary disease, their mechanisms, and the key evidence from trials supporting their use. Drug classes covered were short acting beta agonists (SABA), short acting muscarinic antagonists (SAMA), long acting beta agonists (LABA), long acting antimuscarinics (LAMA), inhaled ...
Stan Ejiofor +2 more
openaire +5 more sources