Results 21 to 30 of about 331,890 (216)

No TWEAK for COPD [PDF]

European Respiratory Journal, 2013
To the Editor: The therapy with the greatest functional benefit in chronic obstructive pulmonary disease (COPD) is pulmonary rehabilitation [1]; while the mode of action is probably multifactorial the functional benefit of pulmonary rehabilitation is associated with strength gain in the quadriceps [2].
A L, Lazaar, B E, Miller, G, Francombe, A, Duvoix, S A, Natanek, M I, Polkey   +5 more
openaire   +2 more sources

Women with COPD [PDF]

Breathe, 2020
Health inequalities regarding gender are extremely prevalent, and specifically in conditions such as COPD. No woman should ever be dismissed in regard to their health and underlying medical history. https://bit.ly/2X7Klmd.
McIvor, Emma R., Saraiva, Isabel, Denning, Jessica, McIvor, R. Andrew   +3 more
openaire   +2 more sources

Women's COPD [PDF]

Frontiers in Medicine, 2022
Chronic obstructive pulmonary disease (COPD) is no longer a respiratory disease that predominantly affects men, to the point where the prevalence among women has equaled that of men since 2008, partly due to their increasing exposure to tobacco and to biomass fuels. Indeed, COPD has become the leading cause of death in women in the USA.
Maéva Zysman, Maéva Zysman, Chantal Raherison-Semjen, Chantal Raherison-Semjen   +3 more
openaire   +4 more sources

Epithelial senescence in idiopathic pulmonary fibrosis is propagated by small extracellular vesicles

Respiratory Research, 2023
Background Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects 3 million people worldwide. Senescence and small extracellular vesicles (sEVs) have been implicated in the pathogenesis of IPF, although how sEVs promote disease ...
Sabha Asghar, Susan Monkley, David J. F. Smith, Richard J. Hewitt, Ken Grime, Lynne A. Murray, Catherine L. Overed-Sayer, Philip L. Molyneaux   +7 more
doaj   +1 more source

Avaliação dos resultados nos ensaios clínicos na DPOC: Da função pulmonar aos marcadores biológicos

Revista Portuguesa de Pneumologia, 2008
Resumo: As sociedades científicas respiratórias europeia e americana (ERS e ATS) constituíram um grupo de trabalho sobre a “Avaliação dos resultados nos ensaios clínicos na DPOC: da função pulmonar aos marcadores biológicos” para informar a ...
M. Cazzola, W. MacNee, F.J. Martinez, K.F. Rabe   +3 more
doaj   +1 more source

Genetics of COPD [PDF]

Annual Review of Physiology, 2020
Although chronic obstructive pulmonary disease (COPD) risk is strongly influenced by cigarette smoking, genetic factors are also important determinants of COPD. In addition to Mendelian syndromes such as alpha-1 antitrypsin deficiency, many genomic regions that influence COPD susceptibility have been identified in genome-wide association studies ...
openaire   +2 more sources

COPD uncovered: an international survey on the impact of chronic obstructive pulmonary disease [COPD] on a working age population [PDF]

, 2011
Background Approximately 210 million people are estimated to have chronic obstructive pulmonary disease [COPD] worldwide. The burden of disease is known to be high, though less is known about those of a younger age.
Neil Barnes, Jones, P, Walker, S, Fletcher Monica J, Barnes, N, Buist, Sonia A., Buist, SA, Van der Molen, Thys, Barnes Neil, Paul Jones, Walsh, JW, Jenkins Christine, Van Der Molen Thys, Jane Upton, Jenkins, Christine, Walsh John W, Jenkins, C, Upton, J, Van Der Molen, T, Sonia A Buist, Fletcher, Monica J., Hutton John, Fletcher, MJ, Upton, Jane, Walker, Samantha, Taylor-Fishwick Judith, Barnes, Neil, Taylor-Fishwick, J, Jenkins, C ; https://orcid.org/, Walker Samantha, Monica J Fletcher, John Hutton, Thys Van Der Molen, Taylor-Fishwick, Judith, Samantha Walker, John W Walsh, Jones, Paul, Jones Paul, Walsh, John W., Hutton, J, Hutton, John, Buist Sonia A, Upton Jane, Judith Taylor-Fishwick, Christine Jenkins   +44 more
core   +2 more sources

Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria

Nature Communications, 2017
Bcl-2 interacting killer (Bik) decreases airway epithelial hyperplasia via apoptosis mediated by calcium release from the endoplasmic reticulum (ER), but the mechanism is unclear. Here the authors show that Bik promotes Bak enrichment at the ER to tether
Yohannes A. Mebratu, Ivan Leyva-Baca, Marc G. Wathelet, Neal Lacey, Hitendra S. Chand, Augustine M. K. Choi, Yohannes Tesfaigzi   +6 more
doaj   +1 more source

STOP: an open label crossover trial to study ICS withdrawal in patients with a combination of obesity and low-inflammatory asthma and evaluate its effect on asthma control and quality of life

BMC Pulmonary Medicine, 2022
Background Asthma patients with obesity often have a high disease burden, despite the use of high-dose inhaled corticosteroids (ICS). In contrast to asthmatics with normal weight, the efficacy of ICS in patients with obesity and asthma is often ...
Jan A. Witte, Gert-Jan Braunstahl, Wouter J. B. Blox, Susan C. van ’t Westeinde, Johannes C. C. M. in ’t Veen, Jasper H. Kappen, Elisabeth F. C. van Rossum   +6 more
doaj   +1 more source

Proprioceptive changes impair balance control in individuals with chronic obstructive pulmonary disease [PDF]

, 2013
Copyright @ 2013 Janssens et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source
Janssens, L, Chris Burtin, Decramer, M., Burtin, C., Alison K McConnell, Janssens Lotte, Marc Decramer, McConnell Alison K., Lotte Janssens, Burtin, Chris, Claeys Kurt, Kurt Claeys, Brumagne, S, Janssens, W, Simon Brumagne, Janssens, Wim, Pijnenburg, M, Claeys, K., Troosters, T., McConnell, AK, Decramer Marc, Brumagne, Simon, Janssens, L., Madelon Pijnenburg, Claeys, Kurt, Pijnenburg, Madelon, Decramer, M, Wim Janssens, Janssens Wim, Claeys, K, Thierry Troosters, Troosters, T, Brumagne, S., McConnell, Alison K., Brumagne Simon, Decramer, Marc, Burtin, C, Pijnenburg, M., Janssens, W., Troosters Thierry, Pijnenburg Madelon, Troosters, Thierry, Janssens, Lotte, Burtin Chris   +43 more
core   +2 more sources