Continuous cough monitoring using ambient sound recording during convalescence from a COPD exacerbation [PDF]
, 2017 Purpose Cough is common in chronic obstructive pulmonary disease (COPD) and is associated with frequent exacerbations and increased mortality. Cough increases during acute exacerbations (AE-COPD), representing a possible metric of clinical deterioration.
Crooks, Michael G. +7 more
core +1 more source
Risk factors for acute exacerbations of COPD in a primary care population: A retrospective observational cohort study [PDF]
, 2014 Objectives: To evaluate risk factors associated with exacerbation frequency in primary care. Information on exacerbations of chronic obstructive pulmonary disease (COPD) has mainly been generated by secondary care-based clinical cohorts.
Hawkins, A +3 more
core +3 more sources
European Respiratory Review, 2018 Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer from exacerbations.
Christian Viniol, C. Vogelmeier
semanticscholar +1 more source
Eosinophilic inflammation in COPD: from an inflammatory marker to a treatable trait
Thorax, 2020 The heterogeneity of chronic obstructive pulmonary disease (COPD) creates many diagnostic, prognostic, treatment and management challenges, as the pathogenesis of COPD is highly complex and the underlying cellular and molecular mechanisms remain poorly ...
B. David +3 more
semanticscholar +1 more source
European Respiratory Review, 2019 Sphingolipids are a distinct class of lipid molecules widely found in nature, principally as cell membrane constituents. After initial uncertainty about their function, sphingolipids have been increasingly recognised to be metabolically active entities involved in many biological processes, including the control of inflammation. Their role as mediators
Raja Chandra Chakinala +4 more
openaire +3 more sources
Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA) and World Allergy Organization (WAO) document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Allergy and Asthma European Network (GA2LEN) [PDF]
, 2016 Evidence that enables us to identify, assess, and access the small airways in asthma and chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma Association) and WAO to take a position on the role of the small airways in these ...
A. Cruz +51 more
core +14 more sources
Airway inflammation in COPD: progress to precision medicine
European Respiratory Journal, 2019 Chronic obstructive pulmonary disease (COPD) is a significant cause of morbidity and mortality worldwide, and its prevalence is increasing. Airway inflammation is a consistent feature of COPD and is implicated in the pathogenesis and progression of COPD,
C. Brightling, Neil J Greening
semanticscholar +1 more source
Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2013 This review article summarizes the main treatments for chronic obstructive pulmonary disease, their mechanisms, and the key evidence from trials supporting their use. Drug classes covered were short acting beta agonists (SABA), short acting muscarinic antagonists (SAMA), long acting beta agonists (LABA), long acting antimuscarinics (LAMA), inhaled ...
Stan Ejiofor, Alice M. Turner
openaire +4 more sources
Multi-morbidities are Not a Driving Factor for an Increase of COPD-Related 30-Day Readmission Risk [PDF]
, 2020 Background and Objective: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the United States. COPD is expensive to treat, whereas the quality of care is difficult to evaluate due to the high prevalence of multi ...
Chukmaitov, Askar +3 more
core +1 more source
Global and regional estimates of COPD prevalence: Systematic review and meta–analysis
Journal of Global Health, 2015 Background The burden of chronic obstructive pulmonary disease (COPD) across many world regions is high. We aim to estimate COPD prevalence and number of disease cases for the years 1990 and 2010 across world regions based on the best available evidence ...
Davies Adeloye +12 more
semanticscholar +1 more source