Results 41 to 50 of about 602,916 (384)

Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD.

open access: yesNew England Journal of Medicine, 2016
BACKGROUND Most guidelines recommend either a long-acting beta-agonist (LABA) plus an inhaled glucocorticoid or a long-acting muscarinic antagonist (LAMA) as the first-choice treatment for patients with chronic obstructive pulmonary disease (COPD) who ...
J. Wedzicha   +9 more
semanticscholar   +1 more source

Prevalence of airflow limitation in outpatients with cardiovascular diseases in Japan. [PDF]

open access: yes, 2014
Background and objectives: Cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) commonly coexist and share common risk factors. The prevalence of COPD in outpatients with a smoking history and CVD in Japan is unknown.
Hagan, GW   +3 more
core   +2 more sources

Air pollution, lung function and COPD: results from the population-based UK Biobank study

open access: yesEuropean Respiratory Journal, 2019
Ambient air pollution increases the risk of respiratory mortality, but evidence for impacts on lung function and chronic obstructive pulmonary disease (COPD) is less well established.
D. Doiron   +6 more
semanticscholar   +1 more source

Does the BCL-2 family member BIK control lung carcinogenesis?

open access: yesMolecular & Cellular Oncology, 2018
Hyperplastic airway epithelial cells may be the cause for increased risk for lung cancer in patients with chronic lung diseases. The B-cell lymphoma 2 (Bcl-2) family member, Bcl-2-interacting killer (BIK), triggers cell death specifically in these ...
Yohannes A. Mebratu, Yohannes Tesfaigzi
doaj   +1 more source

Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF

open access: yesScientific Reports, 2021
The unfolded protein response (UPR) is a direct consequence of cellular endoplasmic reticulum (ER) stress and a key disease driving mechanism in IPF.
Susan Monkley   +16 more
doaj   +1 more source

COPD and cardiovascular disease [PDF]

open access: yes, 2019
COPD is one of the major public health problems in people aged 40 years or above. It is currently the 4th leading cause of death in the world and projected to be the 3rd leading cause of death by 2020.
André, S.   +5 more
core   +3 more sources

Recent advances in the management of chronic obstructive pulmonary disease [version 1; referees: 2 approved]

open access: yesF1000Research, 2017
Novel pharmacotherapies introduce additional options to providers and patients in how to best treat chronic obstructive pulmonary disease (COPD). Emerging data question the role of inhaled corticosteroids in COPD treatment, particularly as combination ...
Sharon R Rosenberg, Ravi Kalhan
doaj   +1 more source

Exercise-Induced Changes in Exhaled NO Differentiates Asthma With or Without Fixed Airway Obstruction From COPD With Dynamic Hyperinflation. [PDF]

open access: yes, 2016
Asthmatic patients with fixed airway obstruction (FAO) and patients with chronic obstructive pulmonary disease (COPD) share similarities in terms of irreversible pulmonary function impairment. Exhaled nitric oxide (eNO) has been documented as a marker of
Chen, LF   +9 more
core   +1 more source

Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population [PDF]

open access: yes, 2019
Various phenotypes exist in asthma and Chronic Obstructive Pulmonary Disease (COPD). These are important to identify in order to guide treatment decisions.
Brusselle, Guy   +4 more
core   +1 more source

Epidemiology of COPD [PDF]

open access: yesEuropean Respiratory Review, 2009
Chronic obstructive pulmonary disease (COPD) is responsible for early mortality, high death rates and significant cost to health systems. The projection for 2020 indicates that COPD will be the third leading cause of death worldwide (from sixth in 1990) and fifth leading cause of years lost through early mortality or handicap (disability-adjusted life ...
P. O. Girodet, Chantal Raherison
openaire   +4 more sources

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