Results 41 to 50 of about 453,081 (334)

Transcriptional down-regulation of suppressor of cytokine signaling (SOCS)-3 in chronic obstructive pulmonary disease [PDF]

, 2013
Background: Tobacco is a leading environmental factor in the initiation of respiratory diseases and causes chronic obstructive pulmonary disease (COPD).
Dinh, Q. Thai, Fischer, Axel, Groneberg, Jan David Alexander, Peiser, Christian, Quarcoo, David, Scholz, Frank R., Springer, Jochen   +6 more
core   +1 more source

Impact of COPD and anemia on motor and cognitive performance in the general older population: results from the English longitudinal study of ageing [PDF]

, 2020
Background: Cognitive and motor-performance decline with age and the process is accelerated by decline in general health. In this study, we aimed to estimate the effects of COPD and HB levels on cognitive and motor performance in the general older ...
Grittner, Ulrike, Kelley, Sean Walter, Padberg, Inken, Rohmann, Jessica Lee, Schneider, Alice, Siegerink, Bob   +5 more
core   +2 more sources

Assessment and Management of Patients with Chronic Cough by Certified Respiratory Educators: A Randomized Controlled Trial

Canadian Respiratory Journal, 2009
BACKGROUND: The value of other health care professionals is increasingly being recognized to compensate for the shortage of physicians in Canada. Chronic cough is one of the most common reasons for consultation with a respirologist. In the present study,
Stephen K Field, Diane P Conley, Amin M Thawer, Richard Leigh, Robert L Cowie   +4 more
doaj   +1 more source

Long-term exposure to outdoor air pollution and the incidence of chronic obstructive pulmonary disease in a national English cohort. [PDF]

, 2014
OBJECTIVES: The role of outdoor air pollution in the incidence of chronic obstructive pulmonary disease (COPD) remains unclear. We investigated this question using a large, nationally representative cohort based on primary care records linked to hospital
A J Kent, Abbey, Adams, Andersen, Anderson, Atkinson, Brook, Carey, Cesaroni, D G Cook, Department of Health, Downs, Eisner, Euler, Euler, Gan, Gershon, Gotschi, Gulliver, H R Anderson, Hajat, Hoek, I M Carey, Jerrett, Krewski, Lim, Noble, Pope, R W Atkinson, Schikowski, Schikowski, Simpson, Sunyer, T P van Staa, Vienneau, Wheeler, Williams   +36 more
core   +1 more source

Six Weeks of Resveratrol Improves Cardiovascular Health in Patients with COPD [PDF]

, 2020
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. One-third of people diagnosed with COPD die of cardiovascular (CV) complications as opposed to pulmonary.
Cobb, Kolton, Goldman, Kendall, Lavender, Rebekah, Rodriguez-Miguelez PhD, Paula   +3 more
core   +1 more source

Possible role of Krüppel-like factor 5 in the remodeling of small airways and pulmonary vessels in chronic obstructive pulmonary disease [PDF]

, 2016
BACKGROUND: Small airway remodeling is an important cause of the airflow limitation in chronic obstructive pulmonary disease (COPD). A large population of patients with COPD also have pulmonary hypertension.
Abe, K, Hashimoto, Y, Ichikawa, T, Ichinose, M, Kikuchi, T, Koarai, A, Numakura, T, Okazaki, T, Onodera, K, Sato, K, Sugiura, H, Tamada, T, Tanaka, R, Yamada, M, Yanagisawa, S   +14 more
core   +2 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Access to N‐Monofluoromethylated (Thio)Carbamates, Formamides, Alkynamides, and Related Derivatives

Angewandte Chemie, EarlyView.
The first general synthetic access to N‐CH₂F and N‐CHRF carbamates, thiocarbamates, formamides, alkynamides, and related compounds is disclosed. The method involves the direct synthesis of carbamoyl fluoride building blocks from readily available amines, followed by their derivatization. Abstract This work presents the first general synthetic access to
Filip G. Zivkovic, Fritz Bahns, Che‐Ming Hsu, Franziska Schoenebeck   +3 more
wiley   +2 more sources

Agreement of administrative pharmacy dispensing with self‐reported use of oral prednisone in US Veterans with rheumatoid arthritis

Arthritis Care &Research, Accepted Article.
Objective Administrative claims are used to evaluate oral glucocorticoid use in rheumatoid arthritis (RA), despite limited evidence to support accuracy. We aimed to evaluate the performance of claims‐based algorithms for glucocorticoid use compared to self‐report in an RA population.
Beth I. Wallace, Bryant R. England, Joshua F. Baker, Michael D. George, Brian C. Sauer, Jorge Rojas, Punyasha Roul, Katherine D. Wysham, Hannah Brubeck, Isaac Smith, Liron Caplan, Paul A. Monach, Gail S. Kerr, Gary Kunkel, Tawnie Braaten, Ted R. Mikuls, Grant W. Cannon   +16 more
wiley   +1 more source

The effects of lung volume reduction treatment on diffusing capacity and gas exchange

European Respiratory Review, 2020
Lung volume reduction (LVR) treatment in patients with severe emphysema has been shown to have a positive effect on hyperinflation, expiratory flow, exercise capacity and quality of life.
Marlies van Dijk, Karin Klooster, Nick H.T. Ten Hacken, Frank Sciurba, Huib. A.M. Kerstjens, Dirk-Jan Slebos   +5 more
doaj   +1 more source