Results 51 to 60 of about 404,062 (356)

NO: COPD and beyond [PDF]

Thorax, 1997
Background. Inhalation of nitric oxide (NO) causes selective pulmonary vasodilation and improves arterial oxygenation in acute respiratory distress syndrome. But some patients do not respond or gas exchange worsens when inhaling NO. We hypothesised that this detrimental effect might be related to the reversion of hypoxic vasconstriction in those ...
A. T. Jones, T. W. Evans
openaire   +3 more sources

Heterogeneity of Rheumatoid Arthritis‐Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations with Disease Outcomes

Arthritis Care &Research, Accepted Article.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis‐associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999‐2021. RA‐ILD patients were
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

Validation of new predictors of mortality and BODE index variants in patients with COPD at moderate altitude

ERJ Open Research
Background COPD ranks as the third leading global cause of mortality. Despite the widespread use of the BODE index and its variants for mortality prediction, their accuracy may be affected by factors like ethnicity, altitude and regional disparities ...
Robinson Robles-Hernández, Gustavo I. Centeno-Saenz, Alejandra Ramírez-Venegas, Ireri Thirion-Romero, Rafael Hernández-Zenteno, Sandra P. Guinto-Ramírez, María C. Maya-García, Diana Villegas-Trejo, Francisco Montiel-López, Lila M. Cordero-Silis, Rogelio Pérez-Padilla   +10 more
doaj   +1 more source

Defining the relationship between COPD and CVD: what are the implications for clinical practice?

Therapeutic Advances in Respiratory Disease, 2018
Cardiovascular diseases (CVDs) are arguably the most important comorbidities in chronic obstructive pulmonary disease (COPD). CVDs are common in people with COPD, and their presence is associated with increased risk for hospitalization, longer length of ...
A. Morgan, R. Zakeri, J. Quint
semanticscholar   +1 more source

Imaging and COPD [PDF]

Jornal Brasileiro de Pneumologia, 2015
1. Laboratorio de Pesquisa em Imagens Medicas, Pavilhao Pereira Filho, Santa Casa de Misericordia de Porto Alegre, Porto Alegre (RS) Brasil. 2. Pontificia Universidade Catolica de Porto Alegre, Porto Alegre (RS) Brasil. COPD involves destruction of alveolar septa in the lungs, associated with small airway dilation that is partially irreversible.(1) The
openaire   +6 more sources

Adipokines and Associations with Incident Osteoporotic Fracture in Patients with Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Purpose We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker, Bryant R. England, Michael D. George, Hannah Brubeck, Brian Sauer, Aleksander Lenert, Punyasha Roul, Geoffrey M. Thiele, Ted R. Mikuls, Katherine D. Wysham   +9 more
wiley   +1 more source

National clinical audit for hospitalised exacerbations of COPD

ERJ Open Research, 2020
Introduction Exacerbations of COPD requiring hospital admission are burdensome to patients and health services. Audit enables benchmarking performance between units and against national standards, and supports quality improvement.
John R. Hurst, Jennifer K. Quint, Robert A. Stone, Yvonne Silove, Jane Youde, C. Michael Roberts   +5 more
doaj   +1 more source

FastCAR: fast correction for ambient RNA to facilitate differential gene expression analysis in single-cell RNA-sequencing datasets

BMC Genomics, 2023
Cell type-specific differential gene expression analyses based on single-cell transcriptome datasets are sensitive to the presence of cell-free mRNA in the droplets containing single cells.
Marijn Berg, Ilya Petoukhov, Inge van den Ende, Kerstin B. Meyer, Victor Guryev, Judith M. Vonk, Orestes Carpaij, Martin Banchero, Rudi W. Hendriks, Maarten van den Berge, Martijn C. Nawijn   +10 more
doaj   +1 more source

Cardiovascular disease and COPD: dangerous liaisons?

European Respiratory Review, 2018
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) frequently occur together and their coexistence is associated with worse outcomes than either condition alone.
K. Rabe, J. Hurst, S. Suissa
semanticscholar   +1 more source

Clinical Outcomes Of Patients Within The Rheumatoid Arthritis Care Pathway Cohort At a Tertiary Care Integrated Delivery Network: A Comparison To Usual Care

Arthritis Care &Research, Accepted Article.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multi‐disciplinary team‐based care. Clinical and insurance claims data were extracted to compare
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source