Results 141 to 150 of about 5,675 (258)
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle +6 more
wiley +1 more source
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation
ABSTRACT Sex is a fundamental yet underexplored determinant of human neuroinflammation. Across autoimmune, neurodegenerative, and post‐infectious neurological syndromes, males and females exhibit consistent differences in disease vulnerability, progression, and immune tone.
Priyanka Saminathan +6 more
wiley +1 more source
Skin Colour in Salamanders Is Modulated by Both Epitranscriptomic Methylation and Gene Expression
ABSTRACT Animal colouration is a key trait in organismal biology, being involved in natural and sexual selection, competition, and communication. Amphibians use their highly diverse colouration in many ecological interactions, but the molecular bases of their colour variation are less well understood than in other vertebrate systems. While the genetic,
Nicholas Strowbridge +3 more
wiley +1 more source
SUMMARY Plants face constant environmental changes and must integrate external and internal cues to coordinate growth, development, reproduction, and stress responses. A major strategy is perception at the cell surface via a large, diverse network of receptors.
Bruno Pok Man Ngou +2 more
wiley +1 more source
Significance Statement Ethylene signaling governs key plant processes, yet how its receptors translate hormone binding and copper coordination into cellular responses remains unclear. Integrating structural biology, spectroscopy, and simulations reveals receptor organization and clustering, advancing a unified mechanistic framework for ethylene ...
Lisa Sophie Kersten +3 more
wiley +1 more source
Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang +7 more
wiley +1 more source
Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking. [PDF]
Michael J. Petris +5 more
openalex +1 more source
Molecular Events Initiating Exit of a Copper-transporting ATPase ATP7B from the Trans-Golgi Network
Nesrin M. Hasan +6 more
openalex +1 more source

