Results 31 to 40 of about 1,462,174 (364)

Elesclomol induces copper‐dependent ferroptosis in colorectal cancer cells via degradation of ATP7A

open access: yesMolecular Oncology, 2021
Cancer cells reprogram their copper metabolism to adapt to adverse microenvironments, such as oxidative stress. The copper chelator elesclomol has been reported to have considerable anticancer efficacy, but the underlying mechanisms remain largely ...
Wei Gao   +5 more
semanticscholar   +1 more source

Midgut Volvulus: A Rare but Fatal Cause of Abdominal Pain in Pregnancy—How Can We Diagnose and Prevent Mortality?

open access: yesObstetrics and Gynecology International, 2020
Midgut volvulus in pregnancy is rare but life-threatening, resulting in high maternal and fetal mortality. This surgical emergency commonly masquerades as symptoms of pregnancy, which together with its low incidence often leads to delay in diagnosis and ...
Eelyn Chong   +4 more
doaj   +1 more source

A Comparative Study on the Condensation Heat Transfer of R-513A as an Alternative to R-134a

open access: yesMachines, 2021
This paper presents the two-phase condensation heat transfer and pressure drop characteristics of R-513A as an alternative refrigerant to R-134a in a 9.52-mm OD horizontal microfin copper tube.
Andreas Karageorgis   +2 more
doaj   +1 more source

Copper and Copper Proteins in Parkinson’s Disease [PDF]

open access: yesOxidative Medicine and Cellular Longevity, 2014
Copper is a transition metal that has been linked to pathological and beneficial effects in neurodegenerative diseases. In Parkinson’s disease, free copper is related to increased oxidative stress, alpha-synuclein oligomerization, and Lewy body formation. Decreased copper along with increased iron has been found insubstantia nigraand caudate nucleus of
Sergio Montes   +4 more
openaire   +3 more sources

Early Silurian (Aeronian) East Point Coral Patch Reefs of Anticosti Island, Eastern Canada: First Reef Recovery from the Ordovician/Silurian Mass Extinction in Eastern Laurentia

open access: yesGeosciences, 2012
An extensive late Aeronian patch reef swarm outcrops for 60–70 km on Anticosti Island, eastern Canada, located in the inner to mid-shelf area of a prominent tropical carbonate platform of southeastern Laurentia, at 20°–25° S paleolatitude of the southern
Jisuo Jin, Paul Copper
doaj   +1 more source

The Outlook for Taiwan’s New President, Lai Ching-te

open access: yesEast Asian Policy
On 13 January 2024, Taiwan elected Lai Ching-te as its new president, marking the first time a single political party won three consecutive times. Despite this victory, the Democratic Progressive Party did not secure a legislative majority, spelling a ...
John F COPPER
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Surface characteristics and molecular interactions of thin films between bubbles by molecular simulations

open access: yesFrontiers in Chemistry
IntroductionWhether in industrial production or daily life, froth plays an important role in many processes. Sometimes, froth exists as a necessity and is also regarded as the typical characteristic of products, e.g., froth on shampoo.
Tiefeng Peng   +3 more
doaj   +1 more source

Cinética de la conversión del sulfuro de cobre a cobre blister

open access: yesRevista de Metalurgia, 2002
La desulfuración del sulfuro cuproso con aire y oxígeno se ha estudiado en dos reactores de laboratorio, en los cuales el gas se sopla sobre la superficie del fundido.
F. Carrillo   +3 more
doaj   +1 more source

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