Results 51 to 60 of about 996,656 (308)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Bioadsorption of Copper(II) Using Halmahera Specific Marine Algae (Sargassum turbinarioides) Encapsulated Calcium Alginate

Indonesian Journal of Chemistry
This study investigated the conditions for bioadsorption of copper(II) using Halmahera marine algae (Sargassum turbinarioides) encapsulated with calcium alginate by batch method.
Dede Ardiansyah Takdir Abubakar Sanawi, Barlah Rumhayati, Qonitah Fardiyah   +2 more
doaj   +1 more source

Influence of copper on the electronic properties of amorphous chalcogenides

, 2005
We have studied the influence of alloying copper with amorphous arsenic sulfide on the electronic properties of this material. In our computer-generated models, copper is found in two-fold near-linear and four-fold square-planar configurations, which ...
A. Zakery, G. J. Adriaenssens, M. Elstner, N. N. Greenwood, S. I. Simdyankin, S. I. Simdyankin, S. R. Elliott, T. A. Niehaus, Th. Frauenheim   +8 more
core   +1 more source

Copper(II) complexes with a flexible oxamato ligand [PDF]

, 2010
We report on a convenient synthesis of the ligand precursor, diethylethylene-1,2-bis(oxamate), (Et2H2oeo, 1), and show how a partial and preferential hydrolysis of the ester group can give rise to the dianionic ligand, (H2oeo)2−.
Martinez Belmonte, M., Price, D.J.
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The Methylococcus capsulatus (Bath) secreted protein, MopE*, binds both reduced and oxidized copper.

PLoS ONE, 2012
Under copper limiting growth conditions the methanotrophic bacterium Methylococcus capsulatus (Bath) secrets essentially only one protein, MopE*, to the medium.
Thomas Ve, Karina Mathisen, Ronny Helland, Odd A Karlsen, Anne Fjellbirkeland, Åsmund K Røhr, K Kristoffer Andersson, Rolf-Birger Pedersen, Johan R Lillehaug, Harald B Jensen   +9 more
doaj   +1 more source

Binary and ternary mixed metal complexes of terminally free peptides containing two different histidyl binding sites [PDF]

, 2013
Copper(II), nickel(II) and zinc(II) complexes of the terminally free peptides AHAAAHG and AAHAAAHG have been studied by combined applications of potentiometric and various spectroscopic techniques, including UV-visible, CD and EPR for copper(II) and UV ...
Anikó Kaluha, Arena, Arena, Camerman, Csilla Kállay, Damante, Damente, Daniele, Daniele Sanna, Di Natale, Farkas, Hureau, Imre Sóvágó, Jancsó, Jószai, Jószai, Józsa, Kozlowski, Kozlowski, Kállay, Kállay, Kállay, La Mendola, Morris, Rabenstein, Rainer, Rajkovic, Sóvágó, Sóvágó, Sóvágó, Timári, Trapaidze, Turi, Valensin, Viktória Jószai, Walter, Wienken, Witkowska, Ágnes Grenács   +38 more
core   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Silicone-modified black peanut shell (BPS) biochar adsorbents: Preparation and their adsorptions for copper(II) from water

Heliyon
Novel silicone-modified biochar adsorbents (BPS-MBCs) were prepared by utilizing waste black peanut shell (BPS) as a raw biochar and gamma-amino-propyl triethoxysilane (silicone) as an inorganic modifier.
Chen Liu, Xin Yan, He-Xin Zhang, Jian-ming Yang, Keun-Byoung Yoon   +4 more
doaj   +1 more source

Enhancement of antimicrobial activities of whole and sub-fractionated white tea by addition of copper (II) sulphate and vitamin C against Staphylococcus aureus; a mechanistic approach

BMC Complementary and Alternative Medicine, 2011
Background Enhancement of antimicrobial plant products e.g. pomegranate extract by copper (II) sulphate is known. Such combinations have applications in various settings, including the identification of novel compositions to study, treat and control ...
Holloway Andrew C, Gould Simon WJ, Fielder Mark D, Naughton Declan P, Kelly Alison F   +4 more
doaj   +1 more source