Results 201 to 210 of about 112,456 (244)
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Molecular Aspects of Medicine, 2005
Iron and copper are essential nutrients, excesses or deficiencies of which cause impaired cellular functions and eventually cell death. The metabolic fates of copper and iron are intimately related. Systemic copper deficiency generates cellular iron deficiency, which in humans results in diminished work capacity, reduced intellectual capacity ...
Miguel, Arredondo, Marco T, Núñez
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Iron and copper are essential nutrients, excesses or deficiencies of which cause impaired cellular functions and eventually cell death. The metabolic fates of copper and iron are intimately related. Systemic copper deficiency generates cellular iron deficiency, which in humans results in diminished work capacity, reduced intellectual capacity ...
Miguel, Arredondo, Marco T, Núñez
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Copper metabolism–related signature for prognosis prediction and MMP13 served as malignant factor for breast cancer [PDF]
HeliyonYingjian Wang, Shoufang Xu, Yunsen Li
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Journal of the American Medical Association, 1956
Copper as a remedy for various ailments has been of interest to physicians for many hundreds of years. It was first recognized as a normal constituent of human blood in 1875, 1 but it was not until 1924 that Elvehjem and coworkers demonstrated the essential nature of copper in mammalian nutrition, particularly in erythropoiesis.
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Copper as a remedy for various ailments has been of interest to physicians for many hundreds of years. It was first recognized as a normal constituent of human blood in 1875, 1 but it was not until 1924 that Elvehjem and coworkers demonstrated the essential nature of copper in mammalian nutrition, particularly in erythropoiesis.
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Comparative metabolism of copper
Journal of the American Veterinary Medical Association, 1987Copper is required in trace amounts for many body functions. The prominent effects of Cu deficiency or Cu toxicosis differs greatly between animal species. Along with iron, Cu is necessary for the transfer of O2 via a cascade of enzymes so that energy may be available for vital body functions without overheating of the tissues through rapid oxidation ...
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Genetic disorders of copper metabolism
Current Opinion in Pediatrics, 1994In this review we discuss four genetic disorders of copper metabolism. Wilson's disease and Indian childhood cirrhosis result from the toxic effects of copper accumulation in the liver. Menkes' disease and, most likely, occipital horn syndrome result from copper deficiency secondary to disturbances in copper transport. The recent cloning and sequencing
K, Petrukhin, T C, Gilliam
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Oral Contraceptives and Copper Metabolism
Nature, 1970It has been known for many years that serum copper is increased during the later stages of pregnancy. Exogenous oestrogens produce an increase in both serum copper and the copper-binding globulin ceruloplasmin and it is therefore not surprising that that all of the popular oral contraceptives containing potent synthetic oestrogens have been reported ...
M, Briggs, J, Austin, M, Staniford
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Genes regulating copper metabolism
Molecular and Cellular Biochemistry, 1998The metabolism of Cu is intimately linked with its nutrition. From gut to enzymes, Cu bioavailability to key enzymes and other components operates through a complex mechanism that uses transport proteins as well as small molecular weight ligands. Steps in Cu transport through the blood, absorption by cells, and incorporation into enzymes are slowly ...
E D, Harris, Y, Qian, M C, Reddy
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Copper Metabolism and Epilepsy: A Preliminary Report
Epilepsia, 1966SUMMARYA comparison is made between the total copper level in the blood of epileptic and asthmatic patients, who have got the same diet during two weeks. A significant higher copper level is found in the epileptic patients, which is a further support of the work of Canelas et al.RÉSUMÉL'auther fait une comparaison du taux de cuivre total dans le sang ...
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Function of Copper in the Metabolism of Iron
Nature, 1967THE importance of copper in the metabolism of iron has been recognized since Hart et al.1 showed that rats become anaemic when fed a diet composed solely of milk, and respond to the administration of iron only if copper is provided in addition. The observation made by a number of workers that, following the administration of copper to rats deficient in
H R, Marston, S H, Allen
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Metabolism and functions of copper in brain
Progress in Neurobiology, 2014Copper is an important trace element that is required for essential enzymes. However, due to its redox activity, copper can also lead to the generation of toxic reactive oxygen species. Therefore, cellular uptake, storage as well as export of copper have to be tightly regulated in order to guarantee sufficient copper supply for the synthesis of copper ...
Ivo F. Scheiber +2 more
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