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Metabolic Disorders of Copper Metabolism
1977Copper, atomic number 29, is an extremely versatile element both outside and inside living cells. The malleability, ductility, and esthetic properties of copper have promoted its use in pottery, ornaments, and currency for centuries. During the more recent decades, the electrical conductivity of copper has had an important role in the advancement of ...
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Metallothionein in Intestinal Copper Metabolism
1979Approximately a decade after Margoshes and Vallee (1) first identified metallothionein, Evans et al. (2) suggested that this sulfhydryl-rich protein may be involved in the metabolism of copper in both the liver and the intestine. Recently, Bremner and Young (3) demonstrated that copper is bound to metallothionein in mammalian liver. Subsequently, after
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Copper metabolism and pediatric cholestasis
Current Opinion in Clinical Nutrition and Metabolic Care, 2011Copper is an essential trace mineral but both deficiency and toxicity need to be avoided. Copper is regulated via excretion by the biliary system and caution was recommended when administered in patients with cholestasis. Recent clinical reports indicate that despite the cholestasis, copper should not be withheld from parenteral nutrition.Transporters ...
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Zinc Interference With Copper Metabolism
JAMA: The Journal of the American Medical Association, 1978Elsewhere in this issue ofThe Journal, Prasad et al (p 2166) describe a manifestation of the toxic effects of zinc in humans that has not been generally appreciated. They report the occurrence of copper deficiency (hypocupremia, leukopenia, and anemia) in a patient treated with ten times the recommended dietary allowance for zinc 1 during a prolonged ...
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Metabolic pathways of copper metabolism
The American Journal of Medicine, 1955J.P. Mahoney +4 more
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