Results 41 to 50 of about 264,643 (200)

The essential roles of metal ions in insect homeostasis and physiology [PDF]

, 2017
Metal ions play distinct roles in living organisms, including insects. Some, like sodium and potassium, are central players in osmoregulation and ‘blood and guts’ transport physiology, and have been implicated in cold adaptation.
Dow, Julian A.T.
core   +1 more source

Copper Metabolism. XII. Influence of Manganese on Metabolism of Copper.

Experimental Biology and Medicine, 1954
Summary1. Administration of large amounts of manganese to rats was associated with an increase in the concentration of copper in plasma and brain, a decrease in the urinary excretion of copper, a decrease in the concentration of copper in the kidneys, no alteration in the concentration of copper in the liver, and microcytic, hypochromic anemia.
C J, GUBLER, D S, TAYLOR, E J, EICHWALD, G E, CARTWRIGHT, M M, WINTROBE   +4 more
openaire   +2 more sources

Paradoxical roles of antioxidant enzymes:Basic mechanisms and health implications [PDF]

, 2015
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from aerobic metabolism, as a result of accidental electron leakage as well as regulated enzymatic processes.
Amit R. Reddi, Arne Holmgren, Chan PH, Chen EP, Chu FF, Daiber A, Elias S. J. Arnér, Geismann C, Hogan B, Jaarsma D, Jian-Hong Zhu, Jin R, Leitzmann C, Li JJ, Li JJ, Lu YP, Makino N, Miranda-Vizuete A, Mirochnitchenko O, Motoori S, Mulder DW, Ogata M, Oury TD, Papaioannou V, Radi R, Sandbach JM, Takahara S, Thimmulappa RK, Tome ME, Vogel U, Wang F, Wen JK, Wen-Hsing Cheng, Wispe JR, Woychik RP, Xin Gen Lei, Ye-Shih Ho, Yongping Bao, Yoshida T   +38 more
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Insights into molecular mechanisms of disease in Neurodegeneration with Brain Iron Accumulation; unifying theories. [PDF]

, 2016
Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterised by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated ...
Adibhatla, Aghajanian, Alazami, Alderson, Andrews, Balboa, Balsinde, Barbeito, Beck, Bosveld, Bras, Bras, Breus, Brissot, Broekemeier, Brunetti, Burn, Campanella, Chen, Cozzi, Crichton, Cui, Curtis, Dall'Armi, Daugherty, Davis, Deas, Dehay, Deng, Deschauer, Di Fonzo, Dick, Duran, Dusi, Eckhardt, Edvardson, Elbaz-Alon, Engel, Friedman, Fukunaga, Gadd, Gitler, Gonzalez-Cuyar, Green, Gregory, Gregory, Grünewald, Haack, Hailey, Hallgren, Hama, Hamasaki, Hartig, Hartig, Hayflick, Hayflick, Hill, Hogarth, Hong, Hortnagel, Houlden, Hönscher, Itoh, Iuso, Jana, Jenkins, Jeong, Jiang, Jin, Kaneko, Keller, Keogh, Kondo, Kono, Kotzbauer, Kruer, Kruer, Kruer, Kruer, Kurz, Kühlbrandt, Landouré, Larsson, Lei, Leonardi, Leoni, Levi, Li, Liou, Lu, Maday, Mahadevan, Malik, Mancuso, Manjithaya, Mariño, McNeill, Moreno, Morgan, Morita, Nemazanyy, Nousbeck, Oide, Ong, Paisan-Ruiz, Paisán-Ruiz, Park, Perry, Pivtoraiko, Poli, Polishchuk, Potter, Proikas-Cezanne, Ramirez, Ramonet, Rana, Riku, Ross, Ross, Rouault, Rouault, Roy, Saitsu, Scherz-Shouval, Schmidt, Schneider, Schneider, Seleznev, Shinzawa, Siudeja, Song, Strokin, Strokin, Tan, Tooze, Tsunemi, Usenovic, Vidal, Walia, Williams, Wu, Xu, Yadrick, Yang, Yoshida, Yoshida, Zhang, Zhou, Zorzi   +148 more
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Influence of Silver Nanoparticles on the Growth of Ascitic and Solid Ehrlich Adenocarcinoma: Focus on Copper Metabolism

Pharmaceutics, 2023
The link between copper metabolism and tumor progression motivated us to use copper chelators for suppression of tumor growth. We assume that silver nanoparticles (AgNPs) can be used for lowering bioavailable copper.
Daria N. Magazenkova, Ekaterina A. Skomorokhova, Mohammad Al Farroukh, Maria S. Zharkova, Zena M. Jassem, Valeria E. Rekina, Olga V. Shamova, Ludmila V. Puchkova, Ekaterina Y. Ilyechova   +8 more
doaj   +1 more source

Effects of Copper and/or Cholesterol Overload on Mitochondrial Function in a Rat Model of Incipient Neurodegeneration [PDF]

, 2013
Copper (Cu) and cholesterol (Cho) are both associated with neurodegenerative illnesses in humans and animals models. We studied the effect in Wistar rats of oral supplementation with trace amounts of Cu (3 ppm) and/or Cho (2%) in drinking water for 2 ...
Arnal, Nathalie, Castillo, Hector Omar, Marra, Carlos Alberto, Tacconi, Maria Josefa   +3 more
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Copper metabolism and cuproptosis in human malignancies: Unraveling the complex interplay for therapeutic insights

Heliyon
Copper, a vital trace element, orchestrates diverse cellular processes ranging from energy production to antioxidant defense and angiogenesis. Copper metabolism and cuproptosis are closely linked in the context of human diseases, with a particular focus ...
K.M. Abdullah, Jyoti B. Kaushal, Simran Takkar, Gunjan Sharma, Zahraa W. Alsafwani, Ramesh Pothuraju, Surinder Kumar Batra, Jawed Akhtar Siddiqui   +7 more
doaj   +1 more source

The pseudosclerotic form (“wing beating tremor”) of Wilson’s disease [PDF]

Romanian Journal of Neurology, 2015
Wilson disease is a rare monogenic, autosomal recessive disorder of copper metabolism, leading to progressive accumulation of copper in different organs, essentially in the liver, brain and cornea. We report a case of a 25 years old man, Caucasian, with “
Alina Poalelungi, Viorel Poalelungi, Daniela Mladin, Bogdan O. Popescu   +3 more
doaj   +1 more source

Abnormal Copper Homeostasis: Mechanisms and Roles in Neurodegeneration

Toxics, 2014
As a cofactor of proteins and enzymes involved in critical molecular pathways in mammals and low eukaryotes, copper is a transition metal essential for life.
Mario Manto
doaj   +1 more source

Nanotechnology connecting copper metabolism and tumor therapy

MedComm – Biomaterials and Applications, 2023
Copper (Cu) is an essential trace element in the human body that is involved in the formation of several natural enzymes, such as superoxide dismutase and cyclooxygenase.
Yongjuan Li, Ya Dong, Xinyao Zhou, Kelong Fan   +3 more
doaj   +1 more source