Results 71 to 80 of about 18,603 (166)

Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak, Rachael Moorin, Jeff Hughes, Karl Gruber, David Youens   +4 more
wiley   +1 more source

Analysis of alkaloids in Coptis chinensis Franch by high performance capillary electrophoresis-electrospray ionization time of flight mass Spectrometry [PDF]

, 2007
A new method for the analysis of alkaloids in Coptis chinensis Franch was established by high performance capillary electrophoresis-electrospray ionization time of flight mass spectrometry (HPCE-ESI-TOF/MS). The real samples were separated by an uncoated
李文龙, 赵恒强, 王小如, Zhao Heng-Qiang, Chen Jun-Hui, 黎先春, Yang Huang-Hao, 陈军辉, 杨黄浩, Wang Xiao-Ru, Lee, Frank Sen-Chun, Li Wen-Hong   +11 more
core  

Study progress of berberine for treating cardiovascular disease

Chronic Diseases and Translational Medicine, 2015
Berberine (BBR) is a natural alkaloid isolated from the Coptis chinensis. While this plant has been used in Chinese medicine for more than 2500 years, interest in its effects in treating cardiovascular disease has been growing in the last decade.
Le-Min Xia, Mei-Hong Luo
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Metabolic Interaction of the Active Constituents ofCoptis chinensisin Human Liver Microsomes [PDF]

Evidence-Based Complementary and Alternative Medicine, 2015
Coptis chinensisis commonly used in traditional Chinese medicine. The study investigated metabolic interaction of the active constituents (berberine, coptisine, palmatine, and jatrorrhizine) ofCoptis chinensisin human liver microsomes. After incubation of the four constituents ofCoptis chinensisin HLMs, the metabolism of the four constituents was ...
Liu, Songcan, Zhang, Xinfeng, Qiu, Furong, Miao, Ping, Shen, Shujiao, Zhu, Leilei, Zeng, Jin, Jiang, Jian   +7 more
openaire   +2 more sources

Isolation, identification, and susceptibility testing of Staphylococcus caprae from dairy goats with mastitis to antibiotics and Chinese herbal medicines

Frontiers in Veterinary Science
IntroductionMastitis outbreaks in dairy goats at a farm in western Jiangxi Province, have recently imposed significant economic losses on farmers. This study aimed to identify the causative pathogen and implement targeted control measures for early ...
Jie Luo, Jie Luo, Yiping Wang, Yiping Wang, Wenya Zheng, Wenya Zheng, Chaolong Xu, Chaolong Xu, Jianhua Chen, Jianhua Chen, Ben Liu, Ben Liu, Xiaoyue Wang, Xiaoyue Wang, Manxin Fang, Manxin Fang   +15 more
doaj   +1 more source

Antibacterial and Antioxidant Activities of Various Medicinal Plants Used in Oriental Medicine

Natural Product Communications, 2013
The antibacterial activities of the ethanol extracts of 35 medicinal plants were screened against Escherichia coli, Bacillus cereus , and Staphylococcus aureus by following standard antimicrobial susceptibility testing procedures. The ethanol extracts of
Junho Seo, Jiyeon Kim, Geon Go, Jung-Suk Sung, Kwang-Geun Lee   +4 more
doaj   +1 more source

The Role and Mechanism of Berberine as a Candidate Drug for the Treatment of Radiation‐Induced Intestinal Injury

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Radiation‐induced intestinal injury (RIII) is among the most common complications of radiotherapy in patients with abdominaltumours. At present, there are no effective methods for reducing the occurrence or severity of RIII. Berberine (BBR) is a quaternary ammonium alkaloid extracted from Coptis chinensis that has antioxidant, anti ...
Xihao Liu, Li Guo, Lu Guo, Lei Zhu, Jianyu Wang, Fei Da, Wei Zhang, Qiaohui Gao, Juan Guo, Xia Miao, Junye Liu   +10 more
wiley   +1 more source

A Multi-Level Strategy Based on Metabolic and Molecular Genetic Approaches for the Characterization of Different Coptis Medicines Using HPLC-UV and RAD-seq Techniques

Molecules, 2018
Coptis plants (Ranunculaceae) to have played an important role in the prevention and treatment human diseases in Chinese history. In this study, a multi-level strategy based on metabolic and molecular genetic methods was performed for the ...
Furong Zhong, Chan Shen, Luming Qi, Yuntong Ma   +3 more
doaj   +1 more source

Advances in the Study of Endometrial Receptivity and Glucose Metabolism Mechanisms in Insulin Resistance

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
This article systematically reviews how insulin resistance (IR) disrupts endometrial receptivity by interfering with glucose metabolism mechanisms, ultimately leading to infertility in patients with Polycystic Ovary Syndrome (PCOS). ABSTRACT Introduction Insulin resistance (IR) is one of the important pathologic bases of polycystic ovary syndrome (PCOS)
Si‐yan Huang, Shao‐rong Chen, Wei‐hong Chen, Ling‐tao Zheng, Jing Xu, Yan‐Chuan Shi, Shu Lin, Qi‐rong Shi   +7 more
wiley   +1 more source