Results 11 to 20 of about 5,413 (203)

The role and mechanisms of cordycepin in inhibiting cancer cells [PDF]

Brazilian Journal of Medical and Biological Research
With the escalating incidence and mortality rates of cancer, there is an ever-growing emphasis on the research of anticancer drugs. Cordycepin, the primary nucleoside antibiotic isolated from Cordyceps militaris, has emerged as a remarkable agent for ...
Gong Yu, Jiahua Peng, Lu Li, Wenbin Yu, Bin He, Bin Xie   +5 more
doaj   +3 more sources

Cordycepin A New Antibiotic [PDF]

, 1951
A strain of the mould Cordyceps militaris (Linn.) Link has been promoted on nitrogenous media to yield solutions which inhibit the growth of several microorganisms. It has been shown that the total activity of the solutions can be absorbed upon activated
Cunningham, Kenneth G
core   +6 more sources

Efficient de novo production of bioactive cordycepin by Aspergillus oryzae using a food-grade expression platform

Microbial Cell Factories, 2023
Background Cordycepin (3′-deoxyadenosine) is an important bioactive compound in medical and healthcare markets. The drawbacks of commercial cordycepin production using Cordyceps spp. include long cultivation periods and low cordycepin yields. To overcome
Sukanya Jeennor, Jutamas Anantayanon, Sarocha Panchanawaporn, Chanikul Chutrakul, Wanwipa Vongsangnak, Kobkul Laoteng   +5 more
doaj   +1 more source

Edible Fungus Compound Cordycepin Protects Against Acetaminophen-Induced Liver Injury. [PDF]

J Clin Lab Anal
This study demonstrates that pretreatment with cordycepin (COR) effectively protects against acetaminophen (APAP)‐induced acute liver injury in mice. COR mitigates liver damage by exerting strong antioxidant, anti‐inflammatory, and anti‐apoptotic effects through the modulation of ER proteostasis, HIF‐1, and PPAR signaling networks.
Fu C, Li S, Shen S, Xu C, Liao J, Lin N.
europepmc   +2 more sources

Cordycepin inhibits proliferation of human keratinocyte cell line HaCaT induced by TNF-α [PDF]

Jichu yixue yu linchuang, 2023
Objective To study the effect of cordycepin on proliferation, apoptosis and inflammatory reaction of human keratinocyte cell line HaCaT induced by TNF-α.
LIANG Huiyong, WEI Qiuhui, DING Ya, PENG Xiaoqing, YAO Jing, SU Qijian
doaj   +1 more source

Cordyceps mushroom with increased cordycepin content by the cultivation on edible insects

Frontiers in Microbiology, 2022
Cordycepin is the major constituent of Cordyceps mushroom (or Cordyceps militaris) with therapeutic potential. Insects are the direct sources of nutrients for Cordyceps in nature.
Ayman Turk, Mohamed A. A. Abdelhamid, Mohamed A. A. Abdelhamid, Sang Won Yeon, Se Hwan Ryu, Solip Lee, Sung Min Ko, Sung Min Ko, Beom Seok Kim, Beom Seok Kim, Seung Pil Pack, Bang Yeon Hwang, Mi Kyeong Lee   +12 more
doaj   +1 more source

Development of an efficient method for separation and purification of cordycepin from liquid fermentation of Cordyceps militaris and analysis of cordycepin antitumor activity

Heliyon, 2023
Cordycepin (3 ′-deoxyadenosine) is the main active component of Cordyceps militaris, which is a chemical marker for quality detection of Cordyceps militaris and has important medicinal development value.
Peng-xiao Liu, Jie-xin Ma, Rui-na Liang, Xiang-wei He, Guo-zhu Zhao   +4 more
doaj   +1 more source

Effects of Cordycepin in Cordyceps militaris during Its Infection to Silkworm Larvae

Microorganisms, 2021
Cordyceps militaris produces cordycepin, a secondary metabolite that exhibits numerous bioactive properties. However, cordycepin pharmacology in vivo is not yet understood. In this study, the roles of cordycepin in C.
Tatsuya Kato, Konomi Nishimura, Ahmad Suparmin, Kazuho Ikeo, Enoch Y. Park   +4 more
doaj   +1 more source

The Role of Autophagy in Anti-Cancer and Health Promoting Effects of Cordycepin

Molecules, 2021
Cordycepin is an adenosine derivative isolated from Cordyceps sinensis, which has been used as an herbal complementary and alternative medicine with various biological activities.
Yu-Ying Chen, Chun-Hsien Chen, Wei-Chen Lin, Chih-Wei Tung, Yung-Chia Chen, Shang-Hsun Yang, Bu-Miin Huang, Rong-Jane Chen   +7 more
doaj   +1 more source

Studies on the biosynthesis of cordycepin [PDF]

Biochimica et Biophysica Acta, 1961
The carboxyl carbons of acetate and isovalerate do not serve to any appreciable extent as precursors of cordycepin, thus arguing against the origin of cordycepose from pathways of isoprenoid biosynthesis. Exogenously added [8-14C]adenine, [I-14C]-glucose, and [6-14C]glucose serve as excellent precursors, the latter two compounds labeling both the base ...
Kredich, Nicholas M., Guarino, Armand J.
openaire   +3 more sources