Results 51 to 60 of about 1,302,762 (259)

Exploring phenotypic variation of diverse bambara groundnut (Vigna subterranea L) origin and development of mini‐core collection for future breeding

Food and Energy Security, 2023
Understanding the phenotypic variation and designing a mini‐core collection is an efficient method to accelerate the genetic gain of bambara groundnut.
Charles U. Uba, Happiness O. Oselebe, Abush A. Tesfaye, Getachew S. Mekonen, Wosene G. Abtew   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Evaluation of the Agricultural and Quality Potential of the New Aubergine Genotype Obtained at the Buzău Plant Genetic Resources Bank

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Horticulture, 2022
Taking into account the increasing demands of farmers and consumers in terms of diversification of the assortment of aubergines marketed in Romanian markets, the Buzau Plant Genetic Resources Bank aims to contribute to its improvement by breeding and ...
Camelia BRATU, Florin STĂNICĂ, Costel VÎNĂTORU, Bianca MUȘAT, Geanina NEGOȘANU   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Morphological Characterization of Bottle Gourd (Lagenaria siceraria (Molina) Standl.) Germplasm and Formation of a Core Collection

Journal of Agricultural Sciences, 2019
Bottle gourd [Lagenaria siceraria (Molina) Standl.] genotypes were collected from different parts of Turkey and a core collection (CC) was established based on morphological characteristics. The collection was grown for morphological characterization and
Halit Yetişir, Nihal Denli, Kahraman Gürcan, Adem Taş   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Genetic diversity analysis and core collection construction of Phyllanthus emblica based on SSR markers [PDF]

Guoshu xuebao
[Objective] The genetic diversity and core collection construction of Phyllanthus emblica were investigated using SSR molecular markers, in order to provide a scientific basis for preservation, genetic breeding and efficient utilization of the germplasm ...
WANG Jianchao, ZHANG Xiaoyan, ZHANG Lijie, LI Tao, XIE Lixue   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source