Results 71 to 80 of about 81,962 (290)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Modelling & integration of advanced propulsion systems [PDF]
, 2008 This research study focuses on the design of advanced propulsion cycles, having as primary design goal the improvement on noise emissions and fuel consumption.
Doulgeris, Georgios C.
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Network Structure and Synergy Characteristics in the Guangdong-Hong Kong-Macao Greater Bay Area
Applied SciencesIn regions where transportation and the economy are closely integrated, optimizing network structure and enhancing synergy are vital for regional integration.
Shaobo Wang +4 more
doaj +1 more source
Red tourism is a distinctive form of tourism in China. Its network attention serves as a typical indicator to measure the level of promotion and publicity for red tourism, as well as an important reflection of its influence.
Lv Xiaoyu (18275645) +2 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Integration of a CGRA Accelerator with a CVA6 RISC-V Core for the Cloud-edge Continuum
The computing continuum is a new paradigm that views the cloud, edge, and fog layers of the Internet of Things as part of a single space where computing tasks can be scheduled on various devices [1]. In this context, edge devices could benefit from application-class processors and reconfigurable accelerators to provide further adaptability and local ...
Otero, Andrés, Granja, Juan
openaire +4 more sources
State-of-the-art survey on resource optimization in edge computing
大数据, 2019 The traditional centralized architecture,known as cloud computing,cannot accommodate such user demands in an efficient and timely manner.To cope with this problem,edge computing architectures have been proposed with the core concept of that“data ...
Zhihao QU +4 more
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source