Results 51 to 60 of about 1,082,336 (265)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

An Investigation of the Magnetic Properties of Iron-based Soft Magnetic Composites Coated by Sodium Silicate Insulator

Journal of Advanced Materials in Engineering, 2018
In this study, iron powder (~45 μm) with the  minimum purity of 99% was insulated by the 1 to 4 wt% sodium silicate insulator (SiO2.3Na2O solution in 40 wt% water) and the 0.5 wt% zinc stearate.
M. Amoohadi, M. Mozaffari, A. R. Gharaati, M. Rezazadeh   +3 more
doaj  

Synergistic Electrical–Magnetic–Thermal Response of Fe Soft Magnetic Composites Enabled by Thiol-Functionalised Silicon Nitride Nanosheet Interfacial Engineering

Magnetochemistry
Pure Fe soft magnetic composites (SMCs) hold a prominent position in cost-sensitive 10–100 kHz medium-to-low-frequency power devices owing to their low raw-material expenditure and high saturation magnetisation.
Shuang Chen, Zhongqiu Fu, Kang Wang, Gongyu Ji, Cheng Liu   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Modeling and Testing of 3D Wound Core Loss of Amorphous Alloy Transformer for Photovoltaic Inverter

Energies
The harmonic content of transformers used in the field of new energy is significantly higher than that of conventional transformers, leading to an abnormal increase in transformer loss during operation.
Peng Chen, Jianwei Han, Xinglong Yao, Xiaohui Wang, Yunfei Yan, Zhe Zhao, Lisong Zhang, Zhanyang Yu, Hao Li   +8 more
doaj   +1 more source

Determination of Core Losses in Open-Core Power Voltage Transformers

IEEE Access, 2018
Power voltage transformers (PVTs) are becoming increasingly present in different substation solutions on a world scale. Such units that are based on the open-core concept introduce several advantages in terms of transformer performance and reliability. This paper provides context for distinct open-core losses, expanding in detail on a measurement-based
Igor Ziger, Bojan Trkulja, Zeljko Stih
openaire   +4 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Enhancing Performance of Permanent Magnet Motor Drives through Equivalent Circuit Models Considering Core Loss

Energies
Permanent magnet motors (PMMs) have emerged as key components in numerous industrial applications due to their high efficiency, compact size, and robust performance characteristics.
Youguang Guo, Yunfei Yu, Haiyan Lu, Gang Lei, Jianguo Zhu   +4 more
doaj   +1 more source

Reduction in Core Loss in Amorphous Cut Cores with Air Gaps

IEEE Translation Journal on Magnetics in Japan, 1989
In order to reduce core losses in amorphous cut cores with air gaps, the effects of ferrite plates attached to the cut surfaces of the cores were investigated. It was learned that the attachment of thin ferrite plates decreases the core loss remarkably in such cores.
Fukunaga, H., Eguchi, T., Mita, T., Ohta, Y., Kakehasi, H.   +4 more
openaire   +2 more sources