Results 51 to 60 of about 480,920 (265)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of Environmental Engineering and Landscape Management, 2019 This study investigated the optimal conditions for preparing desulfurizing stalk carbon, using corn stalk as a raw material and zinc chloride as an activator.
Fen Li +3 more
doaj +1 more source
Peculiarities of a glass-sludge mixture subjected to low-temperature treatment [PDF]
Science of Sintering, 2017 In this work, the specific features of formation of a composite material consisting of a mixture of low-melting ground glass and waste active sludge, which is used for sewage purification, have been considered.
Parra Parra Abigail +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Scalable Training of Mixture-of-Experts Models with Megatron Core
CoRRScaling Mixture-of-Experts (MoE) training introduces systems challenges absent in dense models. Because each token activates only a subset of experts, this sparsity allows total parameters to grow much faster than per-token computation, creating coupled constraints across memory, communication, and computation.
Zijie Yan +44 more
openaire +2 more sources
Thermoelastic Properties of Liquid Fe‐Rich Alloys Under Martian Core Conditions
Geophysical Research Letters, 2023 Seismic measurements made on Mars indicate that the liquid iron‐nickel core is rich in light elements; however, the effects of these light components on the elasticity of Mars’ core remain poorly constrained.
D. Huang +5 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Soft core fluid in a quenched matrix of soft core particles: A mobile mixture in a model gel [PDF]
Physical Review E, 2006 20 pages, 5 figures. Accepted for Phys.
Archer, AJ, Schmidt, M, Evans, R
openaire +4 more sources
Journal of Petroleum Exploration and Production Technology, 2022 Chemical enhanced oil recovery (EOR) methods are shown to sweep the residual oil by altering physical properties of fluids after waterflooding to improve oil recovery.
Lun Zhao +7 more
doaj +1 more source