Results 61 to 70 of about 480,920 (265)
A Mixture Rasch Model Analysis of Data from a Survey of Novice Teacher Core Competencies
International Journal of Contemporary Educational Research, 2023 Although the Rasch model is used to measure latent traits like attitude or ability where there are multiple latent structures within the dataset it is best to use a technique called the Mixture Rasch Model (MRM) which is a combination of a Rasch model ...
Turker Toker, Kent Seıdel
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Buildings, 2023 This work presents a new approach to investigating water conduction properties in real three-dimensional (3D) voids of asphalt mixtures. Three different molding methods were employed for the same grade of asphalt mixture, and the three asphalt mixture ...
Cheng Wan, Qiang Yi, Xiaoning Zhang
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Study of technological features of tubular compressed concrete members in concreting
MATEC Web of Conferences, 2017 The technological features of core concreting were analyzed as the main factor in ensuring of strength and reliability of compressed concrete-filled steel tubular (CFST) members.
Voskobiinyk Olena, Gukasian Olga
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Stochastic blockmodeling of the modules and core of the Caenorhabditis elegans connectome.
PLoS ONE, 2014 Recently, there has been much interest in the community structure or mesoscale organization of complex networks. This structure is characterised either as a set of sparsely inter-connected modules or as a highly connected core with a sparsely connected ...
Dragana M Pavlovic +4 more
doaj +1 more source
Biotechnology for Biofuels, 2010 Background Enzymes for plant cell wall deconstruction are a major cost in the production of ethanol from lignocellulosic biomass. The goal of this research was to develop optimized synthetic mixtures of enzymes for multiple pretreatment/substrate ...
Walton Jonathan D +4 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source