Results 41 to 50 of about 616,913 (244)

Surface soil metal elements variability affected by environmental and soil properties.

PLoS ONE, 2021
Identifying the factors controlling the spatial variability of soil metal elements could be a challenge task due to the interaction of environmental attributes and human activities.
Wei Wu, Yu Li, Mingshu Yan, Lechao Yang, Jiali Lei, Hong-Bin Liu   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

AI-Driven Semantic Framework for Automated Construction Planning and Scheduling with BIM and Digital Twin Integration

Engineering Proceedings
Construction planning and scheduling, including task sequences, constraints, and interdependencies, is poorly structured within digital models such as BIM and Digital Twin and lacks effective integration with planning documents to support scheduling ...
Qais Amarkhil, Mohamed Hegab, Anwar Alroomi   +2 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Serial reduction optimization research of complex product workflow’s accuracy under the time constraint

Advances in Mechanical Engineering, 2016
Model complex production business contains the attributes of completion time, accuracy, and so on; these factors influence each other; and pursuing the balance of these factors is the core idea of the article.
Zhi-yong Luo, Peng Wang, Bo You, Su-xia Zhu   +3 more
doaj   +1 more source

Learning Task Relatedness in Multi-Task Learning for Images in Context

, 2019
Multimedia applications often require concurrent solutions to multiple tasks. These tasks hold clues to each-others solutions, however as these relations can be complex this remains a rarely utilized property.
Hal Daumé, Kingma Diederik P, Kumar Abhishek, Lake Brenden M., Lee Giwoong, Liu Yang, McInnes Leland, Zamir Amir R.   +7 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Rationalization of the parameters of the cylindrical bridge support (theoretical basis)

MATEC Web of Conferences, 2018
Paper deals with a new constructive solution of a massive concrete pillar intended, mostly, for construction of railway and road bridge supports and with procedure of rationalization of its parameters.
Shmukler Valery, Petrova Olena, Mohammad Hammoud   +2 more
doaj   +1 more source

Exploiting the Nature of Repetitive Actions for Their Effective and Efficient Recognition

Frontiers in Computer Science, 2022
In the field of human action recognition (HAR), the recognition of actions with large duration is hindered by the memorization capacity limitations of the standard probabilistic and recurrent neural network (R-NN) approaches that are used for temporal ...
Konstantinos Bacharidis, Konstantinos Bacharidis, Antonis Argyros, Antonis Argyros   +3 more
doaj   +1 more source

Prominent Attribute Modification using Attribute Dependent Generative Adversarial Network

, 2020
Modifying the facial images with desired attributes is important, though challenging tasks in computer vision, where it aims to modify single or multiple attributes of the face image. Some of the existing methods are either based on attribute independent
Islam, Naeem Ul, Lee, Sungmin, Park, Jaebyung   +2 more
core   +1 more source