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Modulation of PAI-1 and tPA Activity and Thrombolytic Effects of Corilagin
Planta Medica, 2003In this study, Charlton's and Tomihisa's methods were modified to investigate the thrombolytic effect of corilagin from the Chinese herbal plant Phyllanthus urinaria L., as well as its effect on carotid artery patency status. The activity of type 1 plasminogen activator inhibitor (PAI-1) in rat plasma or platelet-released substances and tissue-type ...
Zhi-Qiang, Shen +3 more
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Brevifolin, corilagin and other phenols from Geranium thunbergii
Phytochemistry, 1975Kazuko Mori
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IAPP surface-induced aggregation and corilagin's inhibitory effect
Physical Chemistry Chemical PhysicsProteins and macromolecules spontaneously assemble into structures, while surface physical and chemical attributes impart their diverse morphologies.
Shabeena Jegamohan +4 more
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Sensitization of Hep3B hepatoma Cells to Cisplatin and Doxorubicin by Corilagin
Phytotherapy Research, 2014The anticancer action of gallotannins is a well-developed topic. We have demonstrated the in vivo antitumour activity of corilagin on Hep3B hepatoma using the xenograft athymic nude mice model. Here, we further report the potential sensitization of Hep3B hepatoma cells to cisplatin and doxorubicin by corilagin. Our results showed that corilagin is able
Roberto Gambari
exaly +2 more sources
Unraveling corilagin's absorption and metabolism: a multimodal approach
Food & FunctionCorilagin is an ellagitannin, a natural product found in a wide variety of foods, but its absorption and utilization process in the mammalian intestine is still unclear.
Shi-Dan Wang +7 more
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In Vitro BACE1 Inhibitory Activity of Geraniin and Corilagin from Geranium thunbergii
Planta Medica, 2013Generation of amyloid β peptide through the proteolytic process of amyloid precursor protein by β-secretase and γ-secretase is a main casual factor of Alzheimer's disease, since amyloid β peptide is a major and crucial component of senile plaques in Alzheimer's disease brains.
Kumju, Youn, Mira, Jun
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Corilagin enhances wound healing by modulating the macrophage phenotype in diabetic mice
The FASEB JournalAbstract Excessive inflammation is a prominent issue in diabetic wounds, leading to delayed healing or amputation. Corilagin (Cori) is a natural polyphenolic compound with diverse pharmacological activities, particularly its anti‐inflammatory properties.
Yun Li +6 more
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Journal of Chromatography B, 2017
A method for solid-phase extraction (SPE) of corilagin from natural plant extracts based on molecularly imprinted polymers (MIPs) was developed. For the preparation of corilagin-MIP monoliths, 4-vinylpyridine was used as functional monomer, and ethylene glycol dimethacrylate was used as cross-linking monomer, using a mixture of 1-butyl-3 ...
Chao, Wang +5 more
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A method for solid-phase extraction (SPE) of corilagin from natural plant extracts based on molecularly imprinted polymers (MIPs) was developed. For the preparation of corilagin-MIP monoliths, 4-vinylpyridine was used as functional monomer, and ethylene glycol dimethacrylate was used as cross-linking monomer, using a mixture of 1-butyl-3 ...
Chao, Wang +5 more
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Chemico-Biological Interactions, 2019
Diabetes mellitus is the world's most common endocrine disease involving metabolic disorders of carbohydrate, protein and fat. This study was undertaken to investigate the anti-diabetic activity of corilagin, a member of polyphenolic tannins used against hyperglycemia and many other diseases in well-known animal models.
H S, Nandini, Prakash Ramachandra, Naik
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Diabetes mellitus is the world's most common endocrine disease involving metabolic disorders of carbohydrate, protein and fat. This study was undertaken to investigate the anti-diabetic activity of corilagin, a member of polyphenolic tannins used against hyperglycemia and many other diseases in well-known animal models.
H S, Nandini, Prakash Ramachandra, Naik
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Corilagin Regulates Antigen Processing and Presentation by Directly Binding to Inhibit Erap1
International ImmunopharmacologyERAP1 is a critical aminopeptidase that acts as the final "editor" of endogenous antigen peptides in the endoplasmic reticulum, playing a key role in the MHC-I-mediated antigen processing and presentation pathway. It has become a novel target for a broad class of severe autoimmune diseases, referred to as "MHC-I-opathy," as well as for tumor immune ...
Xiangcheng, Sun +9 more
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