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Corilagin Attenuates Radiation-Induced Brain Injury in Mice
Molecular Neurobiology, 2015Cranial irradiation-induced inflammation plays a critical role in the initiation and progression of radiation-induced brain injury (RIBI). Anti-inflammation treatment may provide therapeutic benefits. Corilagin (beta-1-O-galloyl-3, 6-(R)-hexahydroxydiphenoyl-D-glucose, C27H22O18) was a novel member of the tannin family with anti-inflammatory properties
Fan, Tong +9 more
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Sensitization of Hep3B hepatoma Cells to Cisplatin and Doxorubicin by Corilagin
Phytotherapy Research, 2013The anticancer action of gallotannins is a well-developed topic. We have demonstrated the in vivo antitumour activity of corilagin on Hep3B hepatoma using the xenograft athymic nude mice model. Here, we further report the potential sensitization of Hep3B hepatoma cells to cisplatin and doxorubicin by corilagin. Our results showed that corilagin is able
Roberto Gambari +3 more
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ChemInform Abstract: Total Synthesis of (‐)‐Corilagin (V).
ChemInform, 2008AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Hidetoshi Yamada +4 more
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Modulation of PAI-1 and tPA Activity and Thrombolytic Effects of Corilagin
Planta Medica, 2003In this study, Charlton's and Tomihisa's methods were modified to investigate the thrombolytic effect of corilagin from the Chinese herbal plant Phyllanthus urinaria L., as well as its effect on carotid artery patency status. The activity of type 1 plasminogen activator inhibitor (PAI-1) in rat plasma or platelet-released substances and tissue-type ...
Zhi-Qiang, Shen +3 more
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Sensitization of Hep3B Hepatoma Cells to Cisplatin and Doxorubicin by Corilagin
Phytotherapy Research, 2014The anticancer action of gallotannins is a well-developed topic. We have demonstrated the in vivo antitumour activity of corilagin on Hep3B hepatoma using the xenograft athymic nude mice model. Here, we further report the potential sensitization of Hep3B hepatoma cells to cisplatin and doxorubicin by corilagin. Our results showed that corilagin is able
Roberto Gambari, Chung-Hin Chui
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IAPP surface-induced aggregation and corilagin's inhibitory effect
Physical Chemistry Chemical PhysicsProteins and macromolecules spontaneously assemble into structures, while surface physical and chemical attributes impart their diverse morphologies.
Shabeena Jegamohan +4 more
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Unraveling corilagin's absorption and metabolism: a multimodal approach
Food & FunctionCorilagin is an ellagitannin, a natural product found in a wide variety of foods, but its absorption and utilization process in the mammalian intestine is still unclear.
Shi-Dan Wang +7 more
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Genotoxic And Antigenotoxic Effects Of Corilagin In In Vitro Human Lymphocyte Cultures
Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2022Bitkiler tarafından ikincil metabolitler olarak sentezlenen doğal bileşiklerin, serbest radikallerin neden olduğu oksidatif strese ve bunların aracılık ettiği genetik hasara karşı koruyucu etkilerinin olduğu birçok araştırmada bildirilmiştir. Bu doğal bileşikler arasında polifenollerin özellikle güçlü antioksidan aktiviteleri olduğu bilinmektedir ...
Elif TURAN, Gökçe TANER
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Chemico-Biological Interactions, 2019
Diabetes mellitus is the world's most common endocrine disease involving metabolic disorders of carbohydrate, protein and fat. This study was undertaken to investigate the anti-diabetic activity of corilagin, a member of polyphenolic tannins used against hyperglycemia and many other diseases in well-known animal models.
H S, Nandini, Prakash Ramachandra, Naik
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Diabetes mellitus is the world's most common endocrine disease involving metabolic disorders of carbohydrate, protein and fat. This study was undertaken to investigate the anti-diabetic activity of corilagin, a member of polyphenolic tannins used against hyperglycemia and many other diseases in well-known animal models.
H S, Nandini, Prakash Ramachandra, Naik
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Corilagin Regulates Antigen Processing and Presentation by Directly Binding to Inhibit Erap1
International ImmunopharmacologyERAP1 is a critical aminopeptidase that acts as the final "editor" of endogenous antigen peptides in the endoplasmic reticulum, playing a key role in the MHC-I-mediated antigen processing and presentation pathway. It has become a novel target for a broad class of severe autoimmune diseases, referred to as "MHC-I-opathy," as well as for tumor immune ...
Xiangcheng, Sun +9 more
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