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Corrigendum to "Hepatoprotective Effect and Potential Mechanism of Aqueous Extract from <i>Phyllanthus emblica</i> on Carbon-Tetrachloride-Induced Liver Fibrosis in Rats". [PDF]
Evid Based Complement Alternat Medeuropepmc +1 more source
Corilagin, a Promising Medicinal Herbal Agent
Biomedicine and Pharmacotherapy, 2018 Corilagin, a gallotannin, is one of the major active components of many ethnopharmacological plants. It was isolated from Caesalpinia coriaria (Jacq.) Willd. (dividivi) by Schmidt in 1951 for the first time. In the past few decades, corilagin was reported to exhibit anti-tumor, anti-inflammatory and hepatoprotective activities, etc.
Yan-Lin Ming +2 more
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Interaction of Collagen With Corilagin
Colloid and Polymer Science, 2003The molecular mechanism of the stabilization of collagen with hydrolyzable tannin, corilagin, has been investigated using techniques like centrifugation, shrinkage temperature, infrared spectroscopy, and differential scanning calorimetry. Thermodynamic measurements were also carried out for the collagen–corilagin interaction.
Jayakumar Rajadas, Maneesha E Andrews
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Agent in Urgent Need of Clinical Practice: Corilagin
Mini-Reviews in Medicinal Chemistry, 2023Abstract: Corilagin is a naturally occurring water-soluble retrogallic acid tannin, which can be extracted from many kinds of plants. Known at present, it is the main effective ingredient of Phyllanthus urinaria L., Geranium wilfordii Maxim., Phyllanthus matsumurae Hayata, and Trifolium repens L.
XueJia Wang +4 more
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Corilagin Attenuates Aerosol Bleomycin-Induced Experimental Lung Injury [PDF]
International Journal of Molecular Sciences, 2014 Idiopathic pulmonary fibrosis (IPF) is a progressing lethal disease with few clinically effective therapies. Corilagin is a tannin derivative which shows anti-inflammatory and antifibrotics properties and is potentiated in treating IPF. Here, we investigated the effect of corilagin on lung injury following bleomycin exposure in an animal model of ...
Zheng Wang, Li-Jun Ma
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In Vivo Anti-Tumour Activity of Corilagin on Hep3B Hepatocellular Carcinoma
Phytomedicine, 2010We have investigated the potential in vivo anti-tumour activity of corilagin using the Hep3B hepatocellular carcinoma cell line and an athymic nude mice xenograft model. The purity of corilagin was confirmed by high performance liquid chromatographic analysis.
Roberto Gambari +2 more
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Corilagin Protects the Acute Lung Injury by Ameliorating the Apoptosis Pathway
Biomedicine and Pharmacotherapy, 2017 This study elucidates the protective effect of corilagin in acute lung injury rat model. Lung injury induced by ischemia/reperfusion (I/R) model was established by isolating the lungs from the rats. Ischemia was produced for the duration of 1h and thereafter reperfusion was done for 90min in isolated lung in presence and absence of corilagin (20 and ...
Jiudi Lv
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Total Synthesis of (−)-Corilagin
Journal of the American Chemical Society, 2008The synthesis of corilagin was achieved by the integration of the development of the oxidative coupling of the symmetrically protected gallates and the temporarily ring-opened synthetic route for the 3,6-hexahydroxydiphenoyl (HHDP) bridge. This is the first total synthesis of the 1C4/B-ellagitannins, which contain ring-flipped glucose.
Hidetoshi, Yamada +4 more
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Corilagin attenuates osteoclastic osteolysis by enhancing HO‐1 and inhibiting ROS
Journal of Biochemical and Molecular Toxicology, 2022AbstractChinese herbal medicine has well‐established therapeutic effects in various diseases. Corilagin (Cor), a gallic acid tannin in Phyllanthus niruri L., has anti‐inflammatory and antioxidant effects in many diseases. However, its role in osteoclast‐related bone diseases has not been determined.
Shaolin Tan +10 more
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Antihypertensive effect of corilagin in the rat
Canadian Journal of Physiology and Pharmacology, 1995The antihypertensive effect of corilagin, one of the ellagitannins purified from the seeds of Euphoria longana Lam. (Sapindaceae), was investigated in the spontaneously hypertensive rat (SHR). Administration of corilagin into conscious SHR at 5 mg/kg produced an antihypertensive effect equivalent to that induced by 1 mg/kg of guanethidine.
J T, Cheng, T C, Lin, F L, Hsu
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