Acute oral toxicity of the ellagitannin geraniin and a geraniin-enriched extract from Nephelium lappaceum L rind in Sprague Dawley rats [PDF]
Heliyon, 2019 Despite the lack of its toxicity evaluation, traditional herbal products are being widely used for various health indications. Geraniin, an ellagitannin, is a bioactive compound found in many traditional herbal medicines.
Mohanambal Moorthy, Uma Devi Palanisamy
exaly +5 more sources
Ferroptosis‐Inhibitory Effect and Possible Mechanisms of Ellagitannin Geraniin
ChemistryOpen, 2021 The search for safe and effective ferroptosis‐inhibitors has become an important topic. Geraniin, an ellagitannin bearing hexahydroxydiphenoyl (HHDP) and dehydrohexahydroxydiphenoyl (DHHDP) groups, was observed to inhibit erastin‐induced ferroptosis in ...
Dr. Ban Chen +6 more
doaj +5 more sources
Antioxidants, 2022 Geraniin, an ellagitannin, has ameliorative properties against high-fat diet (HFD)-induced metabolic syndrome. Since geraniin has poor bioavailability, we hypothesised the interaction of this compound with gut microbiota as the main mechanism for ...
Mohanambal Moorthy +3 more
doaj +3 more sources
Identification of the plant compound geraniin as a novel Hsp90 inhibitor. [PDF]
PLoS ONE, 2013 Besides its function in normal cellular growth, the molecular chaperone heat shock protein 90 (Hsp90) binds to a large number of client proteins required for promoting cancer cell growth and/or survival.
Antonio Vassallo +4 more
doaj +5 more sources
A preclinical investigation into the potential associations of geraniin with ulcerative colitis alleviation through integrated multi-omics and in vivo analysis [PDF]
Frontiers in MedicineObjectiveThis study aims to investigate the potential molecular mechanisms and alleviating effects of geraniin, a natural polyphenol compound, within a murine model of ulcerative colitis (UC), thereby providing preclinical insights that may inform future
Chang Cheng +4 more
doaj +2 more sources
A Validated Isocratic HPLC–UV Method for the Simultaneous Quantification of Corilagin and Geraniin in Geranium wilfordii Maxim. Extract [PDF]
MoleculesGeranium wilfordii Maxim. is a traditional medicinal plant rich in ellagitannins such as corilagin (CG) and geraniin (GR), which possess antioxidant and anti-inflammatory properties.
Jung-Min Kim +4 more
doaj +2 more sources
Changes in Growth and Polyphenol Content of the Rare Plant Persicaria chinensis Cultivated in a Greenhouse During the Growth Period [PDF]
PlantsThe growth characteristics and changes in major polyphenol content of the rare plant Persicaria chinensis cultivated under greenhouse conditions were investigated to evaluate its potential for large-scale cultivation and industrial use. The fresh and dry
Daeho Choi +3 more
doaj +2 more sources
Elaeocarpus sylvestris (Lour.) Poir.: Phytochemistry and Pharmacological Potential—A Review [PDF]
MoleculesElaeocarpus sylvestris (Lour.) Poir., an evergreen tree native to East and Southeast Asia, has gained increasing scientific attention owing to its broad pharmacological properties.
Sultan Mehtap Büyüker +8 more
doaj +2 more sources
Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro [PDF]
Frontiers in Cellular and Infection MicrobiologyIntroductionRespiratory syncytial virus (RSV) remains a major international public health concern. However, disease treatment is limited to preventive care with monoclonal antibodies and supportive care.
Chao Wang +15 more
doaj +2 more sources
Unlocking the Therapeutic Potential of Ellagitannins: A Comprehensive Review of Key Representatives [PDF]
MoleculesThe present review offers a comprehensive synthesis of the structural diversity, natural occurrence, and therapeutic promise of key ellagitannins (punicalagin, sanguiin H-6, corilagin, geraniin, oenothein B, chebulagic, and chebulinic acids) within the ...
Rositsa Mihaylova +3 more
doaj +2 more sources