Results 21 to 30 of about 797 (162)
Antihypertensive Action of Geraniin in Rats
Journal of Pharmacy and Pharmacology, 1994 AbstractThe effects of geraniin, one of the ellagitannins purified from the leaves of Sapium sebiferum, on blood pressure were investigated in the spontaneously hypertensive rat (SHR). A single intravenous bolus injection of geraniin into anaesthetized SHRs lowered the arterial mean blood pressure in a dose-dependent manner without affecting the heart ...
J T, Cheng, S S, Chang, F L, Hsu
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Assessment of Wound-Healing Properties of Medicinal Plants: The Case of Phyllanthus muellerianus
Frontiers in Pharmacology, 2018 Phyllanthus muellerianus (Family Euphorbiaceae) is a shrub, which is widely distributed in West Africa and employed traditionally as a wound-healing agent especially in Ghana.
Yaw D. Boakye +5 more
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Efficacy of geraniin on dengue virus type-2 infected BALB/c mice
Virology Journal, 2019 Background Dengue continues to be a major international public health concern. Despite that, there is no clinically approved antiviral for treatment of dengue virus (DENV) infections. In this study, geraniin extracted from the rind of Nephelium lappaceum
Siti Aisyah Abdul Ahmad +4 more
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Geraniin as a potential inhibitor of SARS-CoV-2 3CLpro
Natural Product Research, 2022 Geraniin is a polyphenolic compound first isolated from Geranium thunbergii. The major protease (Mpro), namely 3 C-like protease (3CLpro), of coronaviruses is considered an attractive drug target as it is essential for the processing and maturation of viral polyproteins.
Wen-Di, Yu +4 more
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Molecules, 2020 Amariin is an ellagitannin with two dehydrohexahydroxydiphenoyl (DHHDP) moieties connecting glucose 2,4- and 3,6-hydroxy groups. This tannin is predominant in the young leaves of Triadica sebifera and Carpinus japonica. However, as the leaves grow, the 3,
Manami Era +3 more
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Indonesian Biomedical Journal, 2015 BACKGROUND: Diabetes mellitus (DM) is associated with oxidative reaction and hyperglycemic condition. Human body has an antioxidant defense system toward free radical, but overproduction of free radical causing imbalance condition between the free ...
Wahyu Widowati +4 more
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Molecules, 2020 The mosquito-borne viruses dengue (DENV) and Zika (ZIKV) viruses are two medically important pathogens in tropical and subtropical regions of the world. There is an urgent need of therapeutics against DENV and ZIKV, and medicinal plants are considered as
Juliano G. Haddad +8 more
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Geraniin Suppresses the Expression of Cathepsin K in Osteoclasts [PDF]
, 2020 Abstract Background: Cathepsin K (CatK) plays a critical role in osteoclast-induced bone degradation, and it may be a potential therapeutic target for osteoporosis treatment. In our previous experiments, geraniin was reported to have anti-osteoporotic effects against OVX-induced rat osteoporosis and inhibitory effects on bone resorption in ...
Xiaochao Zhang +6 more
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Modificational Changes in Function and Morphology of Cultured Macrophages by Geraniin
Japanese Journal of Pharmacology, 1991 Treatment of peritoneal macrophages with geraniin, isolated from Geranium funbergii, markedly induced the phagocytosis of living yeasts. Marked increases in phagocytosis and acid phosphatase activity in macrophage lysates were observed 24 hr after the beginning of geraniin treatment. As observed by electron microscopy, macrophages that had been treated
Ushio, Yumiko +3 more
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Geraniin supplementation increases human keratinocyte proliferation in serum-free culture
Universa Medicina, 2015 BACKGROUND Various products used in cellular therapy utilize tissue culture techniques requiring keratinocyte culture. An efficient and clinically acceptable keratinocyte culture system requires supplements with mitogenic activity.
Indra Kusuma, Restu Syamsul Hadi
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