Mass Spectrometry-Based Applications in Tannin Analytics: From Qualitative and Quantitative Analyses to Biological Activity. [PDF]
Mass Spectrom RevABSTRACT Tannins are widespread specialized plant metabolites that contribute significantly to the polyphenol content of plant‐based diets. Their effects on human and animal health vary depending on their structure, with potential benefits including antioxidative, antimicrobial, anthelmintic, and anticarcinogenic properties.
Engström MT, Karonen M.
europepmc +2 more sources
Geraniin Alleviates Mouse Laser-Induced Choroidal Neovascularisation by Inhibiting Choroidal Endothelial Cell ACE2/Ang-(1-7)/MasR/IL-10 Pathway. [PDF]
J Cell Mol MedABSTRACT Anti‐vascular endothelial growth factor (VEGF) drugs suppress choroidal neovascularisation (CNV), thus improving vision. However, some patients may have a poor response or develop resistance to anti‐VEGF drugs. Geraniin (GE), a polyphenol isolated from an herb called Phyllanthus amarus, possesses anti‐angiogenic properties. This study aimed to
Lu H +7 more
europepmc +2 more sources
Invalidation of geraniin as a potential inhibitor against SARS-CoV-2 main protease [PDF]
, 2023 Recently, geraniin has been identified as a potent antiviral agent targeting SARS-CoV-2 main protease (Mpro). Considering the potential of geraniin in COVID-19 treatment, a stringent validation for its Mpro inhibition is necessary.
Haohao Yan (9083528) +4 more
core +1 more source
Geraniin inhibits bladder cancer cell growth via regulation of PI3K/AKT signaling pathways [PDF]
, 2020 Purpose: The effect of geraniin on human bladder transitional carcinoma was not clear, this study was thus intended to reveal it and reveal the mechanism.
Xu, Junwei +4 more
core +2 more sources
In Vitro, In Vivo, and Clinical Trial Approaches to Investigate the Effects of Medicinal Plants on Burn Wound Healing: A Systematic Review. [PDF]
Int Wound JABSTRACT Use of synthetic drugs for the treatment of burn wounds has decreased due to adverse effects, and they are gradually being replaced by compounds obtained from natural products, especially medicinal plants. This review focused on pre‐clinical and clinical studies examining the efficacy of medicinal plants in promoting burn wound healing.
Bagheri M +4 more
europepmc +2 more sources
Molecules, 2022 Rambutan (Nephelium lappaceum L.) is a tropical fruit from Asia which has become the main target of many studies involving polyphenolic analysis. Mexico produces over 8 million tons per year of rambutan, generating a huge amount of agro-industrial waste ...
Luis Estrada-Gil +7 more
doaj +1 more source
Metabolites of the Ellagitannin Geraniin and Their Antioxidant Activities [PDF]
Planta Medica, 2011 Different types of ellagitannins are reported to have various biological activities, such as antioxidant, antiviral, and antitumor activities. However, there are few definitive studies on the absorption and metabolism of ellagitannins. This review compares the absorption and metabolism of ellagitannins, and the antioxidant properties of their ...
openaire +2 more sources
The study of anti-hypertensive effect of ellagitannin geraniin in a rat model of diet-induced obesity [PDF]
, 2023 Our group had previously reported that geraniin, an ellagitannin, induced a potent anti-hypertensive effect in a diet-induced obese animal model, accompanied by an improvement of blood glucose and lipid levels.
BOON HEE GOH (16807743)
core +1 more source
Geraniin Inhibits the Entry of SARS-CoV-2 by Blocking the Interaction between Spike Protein RBD and Human ACE2 Receptor [PDF]
, 2021 The coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite the development of vaccines, the emergence of SARS-CoV-2 variants and the absence of effective therapeutics demand the ...
Jang-Gi Choi +5 more
core +1 more source
Molecules, 2020 Amariin is an ellagitannin with two dehydrohexahydroxydiphenoyl (DHHDP) moieties connecting glucose 2,4- and 3,6-hydroxy groups. This tannin is predominant in the young leaves of Triadica sebifera and Carpinus japonica. However, as the leaves grow, the 3,
Manami Era +3 more
doaj +1 more source