Results 31 to 40 of about 797 (162)

Cheminformatics Bioprospection of Broad Spectrum Plant Secondary Metabolites Targeting the Spike Proteins of Omicron Variant and Wild-Type SARS-CoV-2

open access: yesMetabolites, 2022
The spike protein (SP) of SARS-CoV-2 (SC-2) is susceptible to high mutation and has contributed to the multiple waves of COVID-19 being experienced. Hence, targeting the SP remains a logical approach in the development of potent therapeutics against SARS-
Jamiu Olaseni Aribisala   +5 more
doaj   +1 more source

Therapeutic Potential of <i>Acalypha wilkesiana</i> in Type 2 Diabetes: A Review. [PDF]

open access: yesJ Diabetes Res
Background Type 2 diabetes mellitus (T2DM) refers to a chronic metabolic disorder that results from insulin resistance, leading to impaired insulin action and uncontrolled plasma glucose levels. Acalypha wilkesiana is among medicinal plants that are ethnobotanically used in the management of T2DM.
Inshutiyimana S   +5 more
europepmc   +2 more sources

Geraniin ameliorate experimental acute reflux esophagitis via NF-κB regulated anti-inflammatory activities in rats

open access: yesApplied Biological Chemistry, 2019
Repeated reflux of gastric acid and stomach contents into the esophagus leads to esophagus damage, including inflammation, ulcer, and hemorrhage in the epithelium.
Hyeon Hwa Nam   +3 more
doaj   +1 more source

Geraniin supplementation increases human keratinocyte proliferation in serum-free culture [PDF]

open access: yesUniversa Medicina, 2013
Background Various products used in cellular therapy utilize tissue culture techniques requiring keratinocyte culture. An efficient and clinically acceptable keratinocyte culture system requires supplements with mitogenic activity.
Indra Kusuma, Restu Syamsul Hadi
doaj  

Geraniin Protects High-Fat Diet-Induced Oxidative Stress in Sprague Dawley Rats

open access: yesFrontiers in Nutrition, 2018
Geraniin, a hydrolysable polyphenol derived from Nephelium lappaceum L. fruit rind, has been shown to possess significant antioxidant activity in vitro and recently been recognized for its therapeutic potential in metabolic syndrome.
Alexis Panny Y. S. Chung   +4 more
doaj   +1 more source

Valorization of Mexican Rambutan Peel through the Recovery of Ellagic Acid via Solid-State Fermentation Using a Yeast

open access: yesFermentation, 2023
Rambutan (Nephelium lappaceum L.) is a tropical fruit that is originally from Southeast Asia and it was introduced to Mexico in the 1960s; the fruit’s peel is known to possess ellagitannins such as ellagic acid which give the peel great biological ...
Karen De La Rosa-Esteban   +6 more
doaj   +1 more source

Geraniinic acid derivative from the leaves ofPhyllanthus reticulatus [PDF]

open access: yesPharmaceutical Biology, 2010
Chemical constituents as well as cytotoxic and insecticidal activity of the crude methanol extract from the leaves of Phyllanthus reticulatus Poir. (Euphorbiaceae) were investigated. (5R*,6R*)-4,6-Dimethoxycarbonyl-5-[2',3',4'-trihydroxy-6'-(methoxycarbonyl) phenyl]-5,6-dihydro-2H-pyran-2-one (1) along with 3,4,3'-tri-O-methylellagic acid, and methyl ...
Nuch, Pojchaijongdee   +3 more
openaire   +2 more sources

Repurposing antiviral phytochemicals from the leaf extracts of Spondias mombin (Linn) towards the identification of potential SARSCOV-2 inhibitors

open access: yesScientific Reports, 2022
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a pneumonia-like disease with a pattern of acute respiratory symptoms, currently remains a significant public health concern causing tremendous human suffering.
Akwasi Boadu   +4 more
doaj   +1 more source

Dual‐Pathway Defense: Ultramicro‐Pulverised Powder of Polygonum chinense L. and Atractylodes rhizome (PAUP) Rescues Broilers From E. coli‐Triggered Liver Injury Through Modulation of Oxidative Stress and Inflammation

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Reduced Antibiotic residues and resistance concerns: Offers a potential natural alternative to antibiotics for combating E. coli infections in poultry. Provided safer poultry food products: By enhancing liver function, restoring weight gain, and improving feed efficiency, PAUP supports the production of healthier chickens, ultimately contributing to ...
Jia‐Ci Cai   +11 more
wiley   +1 more source

Evaluation of anti-cancer activity of Geraniin in laryngeal cancer Hep-2 cell line

open access: yesMedicine Science
To investigate the anti-cancer activity, including anti-proliferative, anti-inflammatory, anti-metastatic, and apoptotic effects of Geraniin on the laryngeal cancer human epidermoid carcinoma 2 Hep-2 cell line.
Yaser Said Cetin, Mehmet Berkoz
doaj   +1 more source

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