Geraniin-Mediated Apoptosis by Cleavage of Focal Adhesion Kinase through up-Regulation of Fas Ligand Expression in Human Melanoma Cells [PDF]
Geraniin, a form of tannin separated from geranium, causes cell death through induction of apoptosis; however, cell death characteristics for geraniin have not yet been elucidated.
高銘欽;黃麗嬌;郭盛助;林仁混;魏宗德 +1 more
core +1 more source
Geraniin Suppresses the Expression of Cathepsin K in Osteoclasts [PDF]
Abstract Background: Cathepsin K (CatK) plays a critical role in osteoclast-induced bone degradation, and it may be a potential therapeutic target for osteoporosis treatment. In our previous experiments, geraniin was reported to have anti-osteoporotic effects against OVX-induced rat osteoporosis and inhibitory effects on bone resorption in ...
Xiaochao Zhang +6 more
openaire +1 more source
Modificational Changes in Function and Morphology of Cultured Macrophages by Geraniin
Treatment of peritoneal macrophages with geraniin, isolated from Geranium funbergii, markedly induced the phagocytosis of living yeasts. Marked increases in phagocytosis and acid phosphatase activity in macrophage lysates were observed 24 hr after the beginning of geraniin treatment. As observed by electron microscopy, macrophages that had been treated
Ushio, Yumiko +3 more
openaire +3 more sources
The Prebiotic Role of Polyphenols and the Modulation of Gut Microbiota and Metabolic Parameters by Geraniin and its Enriched Extract in Animal Model [PDF]
Geraniin is a natural compound present abundantly in the rambutan rind and has the potential to ameliorate diet-induced metabolic syndrome. This study was carried out to identify whether geraniin's interaction with gut microbiota is the main mechanism ...
MOHANAMBAL MOORTHY (12021053)
core +1 more source
The spike protein (SP) of SARS-CoV-2 (SC-2) is susceptible to high mutation and has contributed to the multiple waves of COVID-19 being experienced. Hence, targeting the SP remains a logical approach in the development of potent therapeutics against SARS-
Jamiu Olaseni Aribisala +5 more
doaj +1 more source
Therapeutic Potential of <i>Acalypha wilkesiana</i> in Type 2 Diabetes: A Review. [PDF]
Background Type 2 diabetes mellitus (T2DM) refers to a chronic metabolic disorder that results from insulin resistance, leading to impaired insulin action and uncontrolled plasma glucose levels. Acalypha wilkesiana is among medicinal plants that are ethnobotanically used in the management of T2DM.
Inshutiyimana S +5 more
europepmc +2 more sources
Hydrolyzable tannins punicalin and geraniin block hepatitis C virus life cycle [PDF]
Hydrolyzable tannins were reported to exert inhibitory effects on the infection and replication of several viruses such as HBV, HSV, HIV and leukemia virus.
Guo, W (via Mendeley Data)
core +1 more source
Effects of geraniin and 17-AAG on cell cycle progression. [PDF]
Percentage of cell cycle stages was analyzed by flow cytometry, (A) PI-stained viable Jurkat cells treated with DMSO, 0.7 µM geraniin or 10 µM 17-AAG for 24 h.
Antonio Vassallo (310891) +4 more
core +1 more source
Geraniin is a diuretic by inhibiting the Na+-K+-2Cl−cotransporter NKCC2 [PDF]
Geranium seemannii Peyr is a perennial plant endemic to central Mexico that has been widely used for its diuretic effect, but the responsible compound of this effect is unknown as well as the mechanism by which the diuretic effect is achieved.
Norma A. Bobadilla +10 more
core +1 more source
Rambutan (Nephelium lappaceum L.) is a tropical fruit that is originally from Southeast Asia and it was introduced to Mexico in the 1960s; the fruit’s peel is known to possess ellagitannins such as ellagic acid which give the peel great biological ...
Karen De La Rosa-Esteban +6 more
doaj +1 more source

