Corilagin in Cancer: A Critical Evaluation of Anticancer Activities and Molecular Mechanisms [PDF]
Molecules, 2019 Corilagin (β-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-d-glucose), an ellagitannin, is one of the major bioactive compounds present in various plants. Ellagitannins belong to the hydrolyzable tannins, a group of polyphenols.
Anupam Bishayee +2 more
exaly +6 more sources
Study on the Effects and Mechanism of Corilagin on A2780 Cell Apoptosis [PDF]
Current Issues in Molecular BiologyPrevious studies have demonstrated corilagin’s inhibitory effects on the growth of various cancer cells. Given the limited research on corilagin’s impact on ovarian cancer, a particularly deadly gynecological malignancy, this study aimed to investigate ...
Ziyang Xu +9 more
doaj +4 more sources
Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway
Heliyon, 2023 Corilagin, a polyphenolic tannic acid compound, showed significant anti-inflammatory activity in atherosclerotic mice. The present study aimed to evaluate the effect and mechanism of corilagin in atherosclerosis by in vivo, in vitro and in molecular ...
Jiayu Zhang +2 more
exaly +5 more sources
Corilagin Ameliorates Con A-Induced Hepatic Injury by Restricting M1 Macrophage Polarization [PDF]
Frontiers in Immunology, 2022 Immune-mediated hepatic injury plays a key role in the initiation and pathogenesis of diverse liver diseases. However, treatment choice for immune-mediated hepatic injury remains limited.
Fenglian Yan +16 more
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Corilagin induces pyroptosis in AML cells by activating the TXNIP-caspase-3-GSDME pathway [PDF]
Annals of HematologyAcute myeloid leukemia (AML) is a hematological malignancy characterized by clonal expansion of myeloid progenitors in the bone marrow, resulting in impaired hematopoiesis.
Ganlu Feng +17 more
doaj +2 more sources
Corilagin attenuates the Parkinsonismin Japanese encephalitis virus induced Parkinsonism
Translational Neuroscience, 2018 This study evaluates the protective effect of corilagin against Parkinsonismin Japanese encephalitis virus (JEV) induced Parkinson’s disease. The JaGAr-01 strain of virus was used to induce JE.
Yanbing Ding +5 more
doaj +3 more sources
Natural Polyphenol Corilagin Enhances Osteogenesis and Chondrogenesis Differentiation of Mesenchymal Stem Cells: Implications for Bone and Cartilage Regeneration [PDF]
MoleculesCorilagin is a hydrolyzable ellagitannin and naturally occurring polyphenolic compound widely distributed in medicinal plants. It is also present in longan (Dimocarpus longan), known as lumyai in Thailand, a subtropical fruit extensively cultivated ...
Thitianan Kulsirirat +3 more
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Corilagin alleviates Staphylococcus aureus pathogenicity by interacting with amidase and α-hemolysin [PDF]
Scientific ReportsStaphylococcus aureus amidase cleaves the peptidoglycan that connect parent and offspring to promote bacterial proliferation, and it also affects the formation of bacterial biofilm.
Fei Teng +7 more
doaj +2 more sources
Corilagin, a promising medicinal herbal agent
Biomedicine and Pharmacotherapy, 2018 Corilagin, a gallotannin, is one of the major active components of many ethnopharmacological plants. It was isolated from Caesalpinia coriaria (Jacq.) Willd. (dividivi) by Schmidt in 1951 for the first time. In the past few decades, corilagin was reported to exhibit anti-tumor, anti-inflammatory and hepatoprotective activities, etc.
Yanlin Ming +2 more
exaly +3 more sources
Protective Effect of Corilagin on Alcoholic Liver Injury
Natural Product CommunicationsObjectives The herbal product corilagin is renowned for its liver-protecting benefits and antioxidant properties. However, the protective role of corilagin in alcoholic liver injury remains unexplored.
Xudan Li +5 more
doaj +2 more sources