Corilagin Ameliorates Macrophages Inflammation in Atherosclerosis Through TLR4-NFκB/MAPK Pathway
Heliyon, 2023 Corilagin, a polyphenolic tannic acid compound, showed significant anti-inflammatory activity in atherosclerotic mice. The present study aimed to evaluate the effect and mechanism of corilagin in atherosclerosis by in vivo, in vitro and in molecular ...
Jiayu Zhang, Yanyun Che
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Corilagin induces pyroptosis in AML cells by activating the TXNIP-caspase-3-GSDME pathway [PDF]
Annals of HematologyAcute myeloid leukemia (AML) is a hematological malignancy characterized by clonal expansion of myeloid progenitors in the bone marrow, resulting in impaired hematopoiesis.
Ganlu Feng +17 more
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Multi-source data integration and ensemble machine learning analysis of the role of Corilagin in regulating endoplasmic reticulum stress and alleviating intestinal ischemia reperfusion injury in mice [PDF]
Frontiers in PharmacologyBackgroundIntestinal ischemia–reperfusion injury (IIRI) is driven by oxidative stress, excessive inflammation, Endoplasmic Reticulum Stress (ERS), and disruption of the intestinal epithelial barrier. Corilagin, a natural ellagitannin with antioxidant and
Zhiyang Wang +10 more
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Corilagin alleviates Staphylococcus aureus pathogenicity by interacting with amidase and α-hemolysin [PDF]
Scientific ReportsStaphylococcus aureus amidase cleaves the peptidoglycan that connect parent and offspring to promote bacterial proliferation, and it also affects the formation of bacterial biofilm.
Fei Teng +7 more
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Natural Polyphenol Corilagin Enhances Osteogenesis and Chondrogenesis Differentiation of Mesenchymal Stem Cells: Implications for Bone and Cartilage Regeneration [PDF]
MoleculesCorilagin is a hydrolyzable ellagitannin and naturally occurring polyphenolic compound widely distributed in medicinal plants. It is also present in longan (Dimocarpus longan), known as lumyai in Thailand, a subtropical fruit extensively cultivated ...
Thitianan Kulsirirat +3 more
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Corilagin in Cancer: A Critical Evaluation of Anticancer Activities and Molecular Mechanisms
Molecules, 2019 Corilagin (β-1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-d-glucose), an ellagitannin, is one of the major bioactive compounds present in various plants. Ellagitannins belong to the hydrolyzable tannins, a group of polyphenols.
Anupam Bishayee +2 more
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A Validated Isocratic HPLC–UV Method for the Simultaneous Quantification of Corilagin and Geraniin in Geranium wilfordii Maxim. Extract [PDF]
MoleculesGeranium wilfordii Maxim. is a traditional medicinal plant rich in ellagitannins such as corilagin (CG) and geraniin (GR), which possess antioxidant and anti-inflammatory properties.
Jung-Min Kim +4 more
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Changes in Growth and Polyphenol Content of the Rare Plant Persicaria chinensis Cultivated in a Greenhouse During the Growth Period [PDF]
PlantsThe growth characteristics and changes in major polyphenol content of the rare plant Persicaria chinensis cultivated under greenhouse conditions were investigated to evaluate its potential for large-scale cultivation and industrial use. The fresh and dry
Daeho Choi +3 more
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Mechanistic Insights into Starch-Polyphenol Complexation: Role of Structural Differences in Galloyl-Based Polyphenols [PDF]
AntioxidantsFruit and vegetable processing by-products, such as peels and pomace, are rich in antioxidant polyphenols and represent promising sources of functional ingredients, but how their galloyl-based polyphenols interact with starch remains insufficiently ...
Liang Wang +4 more
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Study on the Effects and Mechanism of Corilagin on A2780 Cell Apoptosis [PDF]
Current Issues in Molecular BiologyPrevious studies have demonstrated corilagin’s inhibitory effects on the growth of various cancer cells. Given the limited research on corilagin’s impact on ovarian cancer, a particularly deadly gynecological malignancy, this study aimed to investigate ...
Ziyang Xu +9 more
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