Results 31 to 40 of about 1,591 (162)

Investigation of Potential Anticarcinogenic Effects of Corilagin in Lung Cancer Cells

open access: yesClinical and Experimental Health Sciences, 2019
Objective: Lung cancer (LC) is the most extensive reason of cancer associated deaths in men and women in the world. LC categorizes into two main groups due to their molecular clinicopathological features and therapeutic responses. Non-small cell lung cancer (NSCLC) is the main subgroup that consists of nearly 85% of all lung cancer types.
Cagla RENCUZOGULLARİ   +4 more
openaire   +5 more sources

Corilagin Attenuates Allergy and Anaphylactic Reaction by Inhibiting Degranulation of Mast Cells [PDF]

open access: yesMedical Science Monitor, 2018
BACKGROUND This study evaluated the anti-allergic activity of corilagin and also postulates the possible mechanism of its action. MATERIAL AND METHODS Corilagin was given orally at dose of 10, 20, and 40 mg/kg/day. All the animals (guinea pigs, rats, and mice) were sensitized for allergy such as eosinophilia and leukocytosis induced by milk ...
Zhou, Jie   +6 more
openaire   +2 more sources

In vivo and in vitro study on the mechanism of anti-cervical cancer effects of Corilagin in mice

open access: yesJournal of Food Biochemistry, 2023
Corilagin has several pharmacological effects such as anti-tumor, anti-inflammatory, and cardiovascular disease treatment. Our previous studies have shown that the Corilagin can significantly inhibit proliferation of HeLa cells. However, there is no scientific data on the anti-cervical cancer effect of Corilagin in vivo.
Li-Mei Wang   +7 more
openaire   +1 more source

Corilagin Represses Epithelial to Mesenchymal Transition Process Through Modulating Wnt/β-Catenin Signaling Cascade

open access: yesBiomolecules, 2020
Corilagin (CLG), a major component of several medicinal plants, can exhibit diverse pharmacological properties including those of anti-cancer, anti-inflammatory, and hepatoprotective qualities.
Sun Tae Hwang   +4 more
doaj   +1 more source

Investigation of plant metabolites as potential inhibitors of Acinetobacter baumannii: An In-Silico approach

open access: yesInformatics in Medicine Unlocked, 2023
The gram-negative bacteria Acinetobacter baumannii is responsible for a broad spectrum of dangerous nosocomial infections. Acinetobacter baumannii is easily transmitted into the body via mechanical ventilators, open wounds, and intravascular catheters ...
Jamil Ahmed   +7 more
doaj   +1 more source

Sepsis: Epidemiology, Pathophysiology, and Management

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Sepsis remains a major global health burden characterized by substantial geographical heterogeneity and a considerable disease burden in China. Its pathophysiology reflects an interconnected network involving excessive inflammation, oxidative stress, immune imbalance and immunoparalysis, mitochondrial damage, endothelial injury, gut dysbiosis ...
Guang‐Tao Pan   +8 more
wiley   +1 more source

Machine Learning‐Guided Identification of Madecassoside as a Potential RAD51 Modulator That Sensitizes Breast Cancer Cells to Cisplatin

open access: yesChemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
Madecassoside was selected from an in‐house natural product library through machine learning‐based virtual screening and identified as a potential modulator of RAD51‐mediated DNA repair that enhances cisplatin sensitivity in breast cancer cells. ABSTRACT Homologous recombination (HR) is an essential pathway for preserving the genomic stability of cells
Minju Oh, Mi‐Young Jeong, Jiwon Choi
wiley   +1 more source

Antiatherogenic effects of phyllanthus emblica associated with corilagin and its analogue.

open access: yesYakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005
Oxidized low-density lipoprotein (ox-LDL) is the main etiologic factor in atherogenesis, and antioxidants are accepted as effective treatment of atherosclerosis. The aim of this study was to clarify whether the mechanism of the antiatherogenic effects of the herb Phyllanthus Emblica, which is widely used to treat atherosclerosis-related diseases, is ...
DUAN, Weigang, YU, Yun, ZHANG, Luyong
openaire   +2 more sources

Pharmacokinetics and Tissue Distribution in Rats After Oral Administration of Tibetan Medicine Wuwei Leze Powder

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Wuwei Leze Powder (WLP), a classic Tibetan medicine for rheumatoid arthritis, is orally administered and undergoes extensive absorption and metabolism in rats. A total of 56 plasma constituents, including 21 prototypes and 35 metabolites, are identified.
Ping Wang   +7 more
wiley   +1 more source

Corilagin Interferes With Toll-Like Receptor 3-Mediated Immune Response in Herpes Simplex Encephalitis

open access: yesFrontiers in Molecular Neuroscience, 2019
Herpes simplex encephalitis (HSE) is the most common infectious disease of the central nervous system worldwide. However, the pathogenesis of HSE is not clear.
Lu-Jun Li   +8 more
doaj   +1 more source

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