Results 41 to 50 of about 1,591 (162)

Comparative Study of the Antioxidant Mediated Antiaging Properties of Endocarp Extracts From Phoenix dactylifera and Phoenix dactylifera L. via In Silico and In Vitro Analysis

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This comparative study demonstrates that Phoenix dactylifera possesses higher anti‐aging potential compared to Phoenix dactylifera L., which may be attributed to their higher phenolic and flavonoid contents along with stronger free radical scavenging capacity.
Farheen Asaad, Mazhar Abbas, Waqas Haider, Naveed Munir, Maha Gul Zafar, Muhammad Riaz, Muhammad Arshad, Muhammad Arfan Zaman, Tariq Hussain, Muhammad Adnan Ayub, Hasan Ejaz, Quzi Sharmin Akter   +11 more
wiley   +1 more source

Corilagin prevents SARS-CoV-2 infection by targeting RBD-ACE2 binding

Phytomedicine, 2021
The outbreak of coronavirus (SARS-CoV-2) disease caused more than 100,000,000 people get infected and over 2,200,000 people being killed worldwide. However, the current developed vaccines or drugs may be not effective in preventing the pandemic of COVID-19 due to the mutations of coronavirus and the severe side effects of the newly developed vaccines ...
Li Jun Yang, Rui Hong Chen, Sami Hamdoun, Paolo Coghi, Jerome P.L. Ng, David Wei Zhang, Xiaoling Guo, Chenglai Xia, Betty Yuen Kwan Law, Vincent Kam Wai Wong   +9 more
openaire   +2 more sources

Simultaneous quantitative analysis and in vitro anti-arthritic effects of five polyphenols from Terminalia chebula

Frontiers in Physiology, 2023
Background: The fruit of Terminalia chebula has been widely used for a thousand years for treating diarrhea, ulcers, and arthritic diseases in Asian countries.
Fang Liu, Shipeng Zhan, Pu Zhang, Changsheng Jia, Qingzong Zhu, Qing Dai, Mingjie Yu, Lin Cheng, Lirong Xiong, Fengjun Sun, Peiyuan Xia, Xiao Zhang, Jing Hu   +12 more
doaj   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, Volume 59, Issue 8, August 2026.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Corilagin induces apoptosis and autophagy in NRF2‑addicted U251 glioma cell line

Molecular Medicine Reports, 2021
Corilagin, extracted from the Euphorbiaceae and Phyllanthus plants, inhibits the growth of a number of types of tumors. Compared with temozolomide, the traditional chemotherapy drug, corilagin has demonstrated stronger antitumor activity. However, the pharmaceutical mechanism of corilagin in glioma remains unclear.
Liu, Jilan, Qin, Xianyun, Ma, Wenyuan, Jia, Shu, Zhang, Xiaobei, Yang, Xinlin, Pan, Dongfeng, Jin, Feng   +7 more
openaire   +3 more sources

Corilagin relieves atherosclerosis via the toll-like receptor 4 signaling pathway in vascular smooth muscle cells

International Journal of Immunopathology and Pharmacology
Introduction Corilagin possesses a diverse range of pharmacologic bioactivities. However, the specific protective effects and mechanisms of action of corilagin in the context of atherosclerosis remain unclear. In this study, we investigated the impact of
Yujie Wang, Yiqing Li, Yunfei Chen, Jinqian Mao, Jingyu Ji, Shaojun Zhang, Pan Liu, Khrystyna Pronyuk, David Fisher, Yiping Dang, Lei Zhao   +10 more
doaj   +1 more source

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

BioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen, Thomas Roeder, Gerald Rimbach   +2 more
wiley   +1 more source

Corilagin Inhibits Neutrophil Extracellular Trap Formation and Protects against Hydrochloric Acid/Lipopolysaccharide-Induced Acute Lung Injury in Mice by Suppressing the STAT3 and NOX2 Signaling Pathways

Antioxidants
Acute lung injury (ALI) and its severe manifestation, acute respiratory distress syndrome (ARDS), are characterized by uncontrolled inflammatory responses, neutrophil activation and infiltration, damage to the alveolar capillary membrane, and diffuse ...
Fu-Chao Liu, Huang-Ping Yu, Chia-Chih Liao, An-Hsun Chou, Hung-Chen Lee   +4 more
doaj   +1 more source

Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase

Acta Pharmaceutica Sinica B, 2021
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become one major threat to human population health. The RNA-dependent RNA polymerase (RdRp) presents an ideal target of antivirals, whereas nucleoside analogs inhibitor is hindered by the ...
Quanjie Li, Dongrong Yi, Xiaobo Lei, Jianyuan Zhao, Yongxin Zhang, Xiangling Cui, Xia Xiao, Tao Jiao, Xiaojing Dong, Xuesen Zhao, Hui Zeng, Chen Liang, Lili Ren, Fei Guo, Xiaoyu Li, Jianwei Wang, Shan Cen   +16 more
doaj   +1 more source

Recent Advances in the Use of Natural Deep Eutectic Solvents for Natural Product Sample Preparation: Focus on Purification, Characterization, and Sustainability

Journal of Separation Science, Volume 49, Issue 7, July 2026.
ABSTRACT This review examines recent advances in the use of natural deep eutectic solvents (NaDES) for natural product sample preparation, with emphasis on extraction, purification, analytical compatibility, and sustainability. NaDES emerge as versatile, tunable, and biocompatible media that enhance the recovery and stability of diverse phytochemicals ...
Valeria Cedeño‐Fierro, Juan Felipe Grisales‐Mejía, Harlen Gerardo Torres Castañeda, Jose A. Mendiola   +3 more
wiley   +1 more source