Results 41 to 50 of about 1,506 (156)

Investigation of plant metabolites as potential inhibitors of Acinetobacter baumannii: An In-Silico approach

open access: yesInformatics in Medicine Unlocked, 2023
The gram-negative bacteria Acinetobacter baumannii is responsible for a broad spectrum of dangerous nosocomial infections. Acinetobacter baumannii is easily transmitted into the body via mechanical ventilators, open wounds, and intravascular catheters ...
Jamil Ahmed   +7 more
doaj   +1 more source

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

open access: yesBioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen   +2 more
wiley   +1 more source

Recent Advances in the Use of Natural Deep Eutectic Solvents for Natural Product Sample Preparation: Focus on Purification, Characterization, and Sustainability

open access: yesJournal of Separation Science, Volume 49, Issue 7, July 2026.
ABSTRACT This review examines recent advances in the use of natural deep eutectic solvents (NaDES) for natural product sample preparation, with emphasis on extraction, purification, analytical compatibility, and sustainability. NaDES emerge as versatile, tunable, and biocompatible media that enhance the recovery and stability of diverse phytochemicals ...
Valeria Cedeño‐Fierro   +3 more
wiley   +1 more source

Corilagin Interferes With Toll-Like Receptor 3-Mediated Immune Response in Herpes Simplex Encephalitis

open access: yesFrontiers in Molecular Neuroscience, 2019
Herpes simplex encephalitis (HSE) is the most common infectious disease of the central nervous system worldwide. However, the pathogenesis of HSE is not clear.
Lu-Jun Li   +8 more
doaj   +1 more source

Simultaneous quantitative analysis and in vitro anti-arthritic effects of five polyphenols from Terminalia chebula

open access: yesFrontiers in Physiology, 2023
Background: The fruit of Terminalia chebula has been widely used for a thousand years for treating diarrhea, ulcers, and arthritic diseases in Asian countries.
Fang Liu   +12 more
doaj   +1 more source

Investigating the Chemical, Antifungal, and Cytotoxic Properties of Cochlospermum vitifolium Leaves and Stem Bark Extracts

open access: yesChemistry &Biodiversity, Volume 23, Issue 4, April 2026.
This figure contains images created by Freepik from Flaticon. ABSTRACT Comprehensive analysis of the chemical properties and bioactivities of plant extracts is essential for identifying compounds with therapeutic potential. This study analyzed hydroethanolic extracts from the leaves and stem bark of Cochlospermum vitifolium, investigating their ...
Francisco A. S. D. Pinheiro   +9 more
wiley   +1 more source

Antiatherogenic effects of phyllanthus emblica associated with corilagin and its analogue.

open access: yesYakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005
Oxidized low-density lipoprotein (ox-LDL) is the main etiologic factor in atherogenesis, and antioxidants are accepted as effective treatment of atherosclerosis. The aim of this study was to clarify whether the mechanism of the antiatherogenic effects of the herb Phyllanthus Emblica, which is widely used to treat atherosclerosis-related diseases, is ...
DUAN, Weigang, YU, Yun, ZHANG, Luyong
openaire   +2 more sources

The Effects and Mechanisms of Pomegranate on Regulating Lipid Metabolism

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
This study established a high‐fat diet‐induced hyperlipidemia rat model to investigate the lipid‐lowering effects of pomegranate. Pomegranate intervention significantly reduced serum total cholesterol (TC), triglyceride (TG), and low‐density lipoprotein cholesterol (LDL‐C) levels, while alleviating hepatic steatosis by decreasing liver weight and fat ...
Hao Wang   +9 more
wiley   +1 more source

Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase

open access: yesActa Pharmaceutica Sinica B, 2021
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become one major threat to human population health. The RNA-dependent RNA polymerase (RdRp) presents an ideal target of antivirals, whereas nucleoside analogs inhibitor is hindered by the ...
Quanjie Li   +16 more
doaj   +1 more source

Are Tetrapleura tetraptera Phytochemicals Druggable Against SARS‐CoV‐2 Papain‐Like Protein? A Computational Approach

open access: yesNew Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
SARS‐CoV2 Omicron and its substrains are still a critical global health issue and extremely contagious, even with widespread vaccination efforts. Hospitalizations and mortality rates linked to these variants are still prevalent. Current therapeutic options face challenges, including low effectiveness, suboptimal pharmacokinetics, and drug resistance ...
Frank Eric Tatsing Foka   +1 more
wiley   +1 more source

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