Results 21 to 30 of about 1,591 (162)

Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis

Frontiers in Pharmacology, 2022
Intestinal ischemia reperfusion (II/R) is a clinical emergency that frequently occurs in a variety of clinical conditions. Severe intestinal injury results in the release of cytotoxic substances and inflammatory mediators which can activate local ...
Wenlian Li, Kejia Yang, Bin Li, Bin Li, Yunxiang Wang, Jing Liu, Jing Liu, Dapeng Chen, Yunpeng Diao, Yunpeng Diao   +9 more
doaj   +1 more source

Uji molecular docking dan bioinformatika terhadap meniran (Phyllanthus niruri L.) sebagai antivirus SARS-CoV-2 dan antikanker serviks

Menara Perkebunan, 2022
The SARS-CoV-2 virus is a virus that emerged in late 2019 and has yet to find a cure. On the other hand, the incidence of cervical cancer in women continues to increase along with the emergence of cases of COVID-19 caused by SARS-CoV-2. Based on WHO data
Nuha Haifa Arifin, Rifki Febriansah
doaj   +1 more source

Longan flower water extract promotes sleep in mice via the serotonin-melatonin axis. [PDF]

J Sci Food Agric
Abstract BACKGROUND Longan (Dimocarpus longan) flower is an underutilized botanical byproduct rich in polyphenols with reported neuroprotective actions, yet its role in sleep regulation remains unclear. This study aimed to evaluate the sleep‐promoting effects of longan flower water extract (LFWE) and its underlying neurochemical mechanisms in vivo ...
Hung TH, Cheng CP, Chiou WC, Hsia TL, Liu HK, Lu HF, Lai YH, Tsai ST, Chen CJ, Huang C.   +9 more
europepmc   +2 more sources

Corilagin Ameliorates Atherosclerosis in Peripheral Artery Disease via the Toll-Like Receptor-4 Signaling Pathway in vitro and in vivo

Frontiers in Immunology, 2020
We investigated if corilagin can ameliorate or reverse atherosclerotic development via the toll-like receptor 4 (TLR4) signaling pathway in vitro and in vivo.
Yiqing Li, Yujie Wang, Yunfei Chen, Yao Wang, Shaojun Zhang, Pan Liu, Zhilin Chen, Peng Song, Lei Luo, Yingying Luo, Yiping Dang, Lei Zhao   +11 more
doaj   +1 more source

Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis

Frontiers in Cellular and Infection Microbiology, 2017
The IL-13Rα1 signaling pathway and M2 macrophages play crucial roles in schistosome egg-induced hepatic fibrosis via the expression of pro-fibrotic molecules.
Yi-Qing Li, Yun-Fei Chen, Yi-Ping Dang, Yao Wang, Zhen-Zhong Shang, Qian Ma, Yu-Jie Wang, Juan Zhang, Lei Luo, Quan-Qiang Li, Lei Zhao   +10 more
doaj   +1 more source

Corilagin prevents non-alcoholic fatty liver disease via improving lipid metabolism and glucose homeostasis in high fat diet-fed mice

Frontiers in Nutrition, 2022
Non-alcoholic fatty liver disease (NAFLD) has been considered to be one of the most common chronic liver diseases. However, no validated pharmacological therapies have been officially proved in clinic due to its complex pathogenesis.
Mingjuan Liao, Rong Zhang, Yongling Wang, Ziming Mao, Jing Wu, Huaqi Guo, Kaiwen Zhang, Yu Jing, Caoxu Zhang, Huaidong Song, Xia Chen, Gang Wei, Gang Wei, Gang Wei, Gang Wei   +14 more
doaj   +1 more source

Ellagitannin, Phenols, and Flavonoids as Antibacterials from Acalypha arvensis (Euphorbiaceae)

Plants, 2022
There is a significant need to gain access to new and better antibacterial agents. Acalypha arvensis, a plant from the Euphorbiaceae family, has been used in traditional medicine for centuries to treat infectious diseases.
Ever A. Ble-González, Abraham Gómez-Rivera, Alejandro Zamilpa, Ricardo López-Rodríguez, Carlos Ernesto Lobato-García, Patricia Álvarez-Fitz, Ana Silvia Gutierrez-Roman, Ma Dolores Perez-García, Alejandro Bugarin, Manasés González-Cortazar   +9 more
doaj   +1 more source

The Effect and Mechanism of Corilagin from Euryale Ferox Salisb Shell on LPS-Induced Inflammation in Raw264.7 Cells

Foods, 2023
(1) Background: Euryale ferox Salisb is a large aquatic plant of the water lily family and an edible economic crop with medicinal value. The annual output of Euryale ferox Salisb shell in China is higher than 1000 tons, often as waste or used as fuel ...
Minrui Wu, Yuhan Jiang, Junnan Wang, Ting Luo, Yang Yi, Hongxun Wang, Limei Wang   +6 more
doaj   +1 more source

Chemical variability of phenolic compounds in Phyllanthus niruri

Eclética Química, 2023
Phyllanthus niruri L. has been used in folk medicine to treat hepatitis, diabetes, urinary tract disorders, and renal calculi. Here, the chemical differences among its organs and the seasonal chemical variability in the aerial parts were evaluated.
Ingrid Albrecht, Natália Coelho da Silva, Flávio Alexandre Carvalho, Fernando Bombarda Oda, André Gonzaga dos Santos   +4 more
doaj   +1 more source

Chemical Characterization, Antilipidemic Effect and Anti-Obesity Activity of Ludwigia octovalvis in a Murine Model of Metabolic Syndrome

Plants, 2023
Ludwigia octovalvis (Jacq.) P.H. Raven is widely used in traditional medicine for different illnesses, including diabetes and hypertension. However, its impact on lipotoxicity and metabolic syndrome in vivo has not been addressed.
Dulce Lourdes Morales-Ferra, Miguel Ángel Zavala-Sánchez, Enrique Jiménez-Ferrer, Celeste Trejo-Moreno, Manasés González-Cortazar, Claudia I. Gamboa-Gómez, Fernando Guerrero-Romero, Alejandro Zamilpa   +7 more
doaj   +1 more source