Results 11 to 20 of about 1,591 (162)

Corilagin attenuates the Parkinsonismin Japanese encephalitis virus induced Parkinsonism

Translational Neuroscience, 2018
This study evaluates the protective effect of corilagin against Parkinsonismin Japanese encephalitis virus (JEV) induced Parkinson’s disease. The JaGAr-01 strain of virus was used to induce JE.
Yanbing Ding, Lixia Huang, Jun Chen, Song Hu, Fahu Yuan, Jinwen Tu   +5 more
doaj   +3 more sources

Corilagin Ameliorates Con A-Induced Hepatic Injury by Restricting M1 Macrophage Polarization [PDF]

Frontiers in Immunology, 2022
Immune-mediated hepatic injury plays a key role in the initiation and pathogenesis of diverse liver diseases. However, treatment choice for immune-mediated hepatic injury remains limited.
Fenglian Yan, Fenglian Yan, Dalei Cheng, Dalei Cheng, Haiyan Wang, Haiyan Wang, Min Gao, Junfeng Zhang, Junfeng Zhang, Hongyan Cheng, Hongyan Cheng, Changying Wang, Changying Wang, Hui Zhang, Hui Zhang, Huabao Xiong, Huabao Xiong   +16 more
doaj   +3 more sources

Protective Effect of Corilagin on Alcoholic Liver Injury

Natural Product Communications
Objectives The herbal product corilagin is renowned for its liver-protecting benefits and antioxidant properties. However, the protective role of corilagin in alcoholic liver injury remains unexplored.
Xudan Li, Xuan Li, Yuan Deng, Lianghua Chen, Zhizhong Zheng, Yanlin Ming   +5 more
doaj   +2 more sources

Unlocking the Therapeutic Potential of Ellagitannins: A Comprehensive Review of Key Representatives [PDF]

Molecules
The present review offers a comprehensive synthesis of the structural diversity, natural occurrence, and therapeutic promise of key ellagitannins (punicalagin, sanguiin H-6, corilagin, geraniin, oenothein B, chebulagic, and chebulinic acids) within the ...
Rositsa Mihaylova, Viktoria Elincheva, Georgi Momekov, Rumyana Simeonova   +3 more
doaj   +2 more sources

Comprehensive Analysis of Metabolic Changes in Mice Exposed to Corilagin Based on GC-MS Analysis [PDF]

Drug Design, Development and Therapy
Biao Xu,1,* Changshui Wang,2,* Xiaodong Zhu,2 Li Zhu,3 Guangkui Han,2 Changmeng Cui2 1Clinical Medical School, Jining Medical University, Jining, 272067, People’s Republic of China; 2Department of Neurosurgery, Affiliated Hospital of Jining ...
Xu B, Wang C, Zhu X, Zhu L, Han G, Cui C
doaj   +2 more sources

Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7) [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): Inflammation is thought to be the common pathophysiological basis for several disorders. Corilagin is one of the major active compounds which showed broad-spectrum biological and therapeutic activities, such as antitumor, hepatoprotective ...
Wahyu Widowati, Hanna Kusuma, Seila Arumwardana, Ervi Afifah, Cintani Wahyuni, Cahyaning Wijayanti, Muhamad Maulana, Rizal Rizal   +7 more
doaj   +1 more source

Effects of Corilagin on Lipopolysaccharide-Induced Acute Lung Injury via Regulation of NADPH Oxidase 2 and ERK/NF-κB Signaling Pathways in a Mouse Model

Biology, 2022
Acute lung injury (ALI) and acute respiratory distress syndrome are clinically life-threatening diseases. Corilagin, a major polyphenolic compound obtained from the herb Phyllanthus urinaria, has anti-inflammatory and antioxidant properties, and in this ...
Fu-Chao Liu, Chia-Chih Liao, Hung-Chen Lee, An-Hsun Chou, Huang-Ping Yu   +4 more
doaj   +1 more source

A network-based analysis of key pharmacological pathways of Corilagin acting on Breast cancer and experimental validation [PDF]

E3S Web of Conferences, 2020
The combination of network pharmacological methods and experimental verification has revealed the underlying molecular mechanism of Corilagin in the treatment of breast cancer.
Zhong Xue, Tang Jintian, Long Wenyue, Cai Xu, Wang Huiguo, Li Qian   +5 more
doaj   +1 more source

Corilagin: A Novel Antivirulence Strategy to Alleviate Streptococcus pneumoniae Infection by Diminishing Pneumolysin Oligomers

Molecules, 2022
Pneumolysin (PLY) is a significant virulence factor of Streptococcus pneumoniae (S. pneumoniae), able to break through the defense system of a host and mediate the occurrence of a series of infections. Therefore, PLY as the most ideal target to prevent S.
Qiushuang Sheng, Xiaoning Hou, Nan Wang, Minda Liu, Haoyu Zhu, Xuming Deng, Xiaoying Liang, Gefu Chi   +7 more
doaj   +1 more source

Role of NADPH Oxidase-Derived ROS-Mediated IL-6/STAT3 and MAPK/NF-κB Signaling Pathways in Protective Effect of Corilagin against Acetaminophen-Induced Liver Injury in Mice

Biology, 2023
Acetaminophen (APAP) overdose causes acute liver injury via oxidative stress, uncontrolled inflammatory response, and subsequent hepatocyte death. Nicotinamide adenine dinucleotide phosphate oxidase (NOX) is a potent source of cellular reactive oxygen ...
Fu-Chao Liu, Hung-Chen Lee, Chia-Chih Liao, An-Hsun Chou, Huang-Ping Yu   +4 more
doaj   +1 more source