A Validated Isocratic HPLC–UV Method for the Simultaneous Quantification of Corilagin and Geraniin in Geranium wilfordii Maxim. Extract [PDF]
MoleculesGeranium wilfordii Maxim. is a traditional medicinal plant rich in ellagitannins such as corilagin (CG) and geraniin (GR), which possess antioxidant and anti-inflammatory properties.
Jung-Min Kim +4 more
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Corilagin Attenuates Aerosol Bleomycin-Induced Experimental Lung Injury [PDF]
International Journal of Molecular Sciences, 2014 Idiopathic pulmonary fibrosis (IPF) is a progressing lethal disease with few clinically effective therapies. Corilagin is a tannin derivative which shows anti-inflammatory and antifibrotics properties and is potentiated in treating IPF. Here, we investigated the effect of corilagin on lung injury following bleomycin exposure in an animal model of ...
Zheng Wang, Ma Li-Jun
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Changes in Growth and Polyphenol Content of the Rare Plant Persicaria chinensis Cultivated in a Greenhouse During the Growth Period [PDF]
PlantsThe growth characteristics and changes in major polyphenol content of the rare plant Persicaria chinensis cultivated under greenhouse conditions were investigated to evaluate its potential for large-scale cultivation and industrial use. The fresh and dry
Daeho Choi +3 more
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Mechanistic Insights into Starch-Polyphenol Complexation: Role of Structural Differences in Galloyl-Based Polyphenols [PDF]
AntioxidantsFruit and vegetable processing by-products, such as peels and pomace, are rich in antioxidant polyphenols and represent promising sources of functional ingredients, but how their galloyl-based polyphenols interact with starch remains insufficiently ...
Liang Wang +4 more
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Unlocking the Therapeutic Potential of Ellagitannins: A Comprehensive Review of Key Representatives [PDF]
MoleculesThe present review offers a comprehensive synthesis of the structural diversity, natural occurrence, and therapeutic promise of key ellagitannins (punicalagin, sanguiin H-6, corilagin, geraniin, oenothein B, chebulagic, and chebulinic acids) within the ...
Rositsa Mihaylova +3 more
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Corilagin protects the acute lung injury by ameliorating the apoptosis pathway
Biomedicine and Pharmacotherapy, 2017 This study elucidates the protective effect of corilagin in acute lung injury rat model. Lung injury induced by ischemia/reperfusion (I/R) model was established by isolating the lungs from the rats. Ischemia was produced for the duration of 1h and thereafter reperfusion was done for 90min in isolated lung in presence and absence of corilagin (20 and ...
Shixun, Guo +3 more
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Comprehensive Analysis of Metabolic Changes in Mice Exposed to Corilagin Based on GC-MS Analysis [PDF]
Drug Design, Development and TherapyBiao Xu,1,* Changshui Wang,2,* Xiaodong Zhu,2 Li Zhu,3 Guangkui Han,2 Changmeng Cui2 1Clinical Medical School, Jining Medical University, Jining, 272067, People’s Republic of China; 2Department of Neurosurgery, Affiliated Hospital of Jining ...
Xu B, Wang C, Zhu X, Zhu L, Han G, Cui C
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Corilagin alleviates atherosclerosis by inhibiting NLRP3 inflammasome activation via the Olfr2 signaling pathway in vitro and in vivo [PDF]
Frontiers in ImmunologyIntroductionAtherosclerosis, a leading cause of global cardiovascular mortality, is characterized by chronic inflammation. Central to this process is the NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome, which significantly influences ...
Jinqian Mao +12 more
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In Vitro Inhibitory Activity of Corilagin and Punicalagin Against Toxoplasma gondii and Their Mechanism(s) of Action [PDF]
AntibioticsBackground/Objectives: Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. The parasite infection in humans continues to rise due to an increasing seroprevalence rate in domestic and wild warm-blooded animals that serve as a major reservoir ...
Nicole T. Green-Ross +5 more
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High-Resolution LC-MS Simultaneous Quantification of Forty-Six Compounds from Jatropha podagrica Fruit Recommends Four Top Antioxidant Contributors as Q-Markers [PDF]
MoleculesThere has been no chemical analysis of the fruit of medicinal plant Jatropha podagrica until now. The current study aimed to qualitatively and quantitatively analyze the J.
Rongxin Cai +7 more
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