Results 51 to 60 of about 1,506 (156)

Corilagin relieves atherosclerosis via the toll-like receptor 4 signaling pathway in vascular smooth muscle cells

International Journal of Immunopathology and Pharmacology
Introduction Corilagin possesses a diverse range of pharmacologic bioactivities. However, the specific protective effects and mechanisms of action of corilagin in the context of atherosclerosis remain unclear. In this study, we investigated the impact of
Yujie Wang, Yiqing Li, Yunfei Chen, Jinqian Mao, Jingyu Ji, Shaojun Zhang, Pan Liu, Khrystyna Pronyuk, David Fisher, Yiping Dang, Lei Zhao   +10 more
doaj   +1 more source

Corilagin Inhibits Neutrophil Extracellular Trap Formation and Protects against Hydrochloric Acid/Lipopolysaccharide-Induced Acute Lung Injury in Mice by Suppressing the STAT3 and NOX2 Signaling Pathways

Antioxidants
Acute lung injury (ALI) and its severe manifestation, acute respiratory distress syndrome (ARDS), are characterized by uncontrolled inflammatory responses, neutrophil activation and infiltration, damage to the alveolar capillary membrane, and diffuse ...
Fu-Chao Liu, Huang-Ping Yu, Chia-Chih Liao, An-Hsun Chou, Hung-Chen Lee   +4 more
doaj   +1 more source

ALDH2 Mediated Ferroptosis Regulation in Ischemia–Reperfusion Injury

Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT Ischemia–reperfusion injury (IRI) is a common complication in diverse clinical settings, including myocardial infarction, stroke, organ transplantation and major surgery. Its pathological core lies in the metabolic disruption caused by blood flow cessation, followed by oxidative stress, inflammatory cascades and cell death upon reperfusion ...
Liang Han, Wen Zhai
wiley   +1 more source

Apoptotic and genomic effects of corilagin on SKOV3 ovarian cancer cell line

OncoTargets and Therapy, 2017
Corilagin is a member of the tannin family and has been isolated from traditional Chinese medicinal plants, such as Phyllanthus spp. Corilagin has anti-inflammatory, antioxidative, antiatherogenic, and antihypertensive effects in various experimental models.
Rukset Attar, Zeynep Birsu Cincin, Elif Sinem Bireller, Bedia Cakmakoglu   +3 more
openaire   +5 more sources

Corilagin induces apoptosis and autophagy in NRF2‑addicted U251 glioma cell line

Molecular Medicine Reports, 2021
Corilagin, extracted from the Euphorbiaceae and Phyllanthus plants, inhibits the growth of a number of types of tumors. Compared with temozolomide, the traditional chemotherapy drug, corilagin has demonstrated stronger antitumor activity. However, the pharmaceutical mechanism of corilagin in glioma remains unclear.
Liu, Jilan, Qin, Xianyun, Ma, Wenyuan, Jia, Shu, Zhang, Xiaobei, Yang, Xinlin, Pan, Dongfeng, Jin, Feng   +7 more
openaire   +3 more sources

Recent advances in animal models for pathological scar research: A comprehensive review of experimental approaches and translational relevance

Animal Models and Experimental Medicine, Volume 9, Issue 1, Page 59-71, January 2026.
Animal models remain indispensable in the study of pathological scars, each offering unique advantages and constraints. Their integration with in vitro and ex vivo systems is key to developing personalized, clinically translatable antifibrotic therapies. Abstract Pathological scarring, manifested in the form of hypertrophic scars (HTS) and keloid scars
Diana‐Larisa Ancuța, Mariana Văduva, Cristin Coman, Iuliana Caraș   +3 more
wiley   +1 more source

Corilagin enhances the anti-tumor activity of 5-FU by downregulating the expression of GRP 78

Scientific Reports, 2023
Colorectal cancer is one of the most common malignancies worldwide. Although initially effective, patients who receive chemotherapy ultimately experience various complications and develop chemo-resistance, leading to cancer recurrence.
Simin Li, Xinquan Li, Xiliang Yang, Yumeng Lei, Mingxin He, Xiaochen Xiang, Qingming Wu, Hongyun Liu, Jiadun Wang, Qiang Wang   +9 more
doaj   +1 more source

Molecular Dynamics Simulation of Bioactive Compounds Against Six Protein Target of Sars-Cov-2 As Covid-19 Antivirus Candidates

Jurnal Kimia Valensi, 2021
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the virus that causes Coronavirus 2019 (COVID-19). To date, there has been no proven effective drug for the treatment or prevention of COVID-19.
Fikry Awaluddin, Irmanida Batubara, Setyanto Tri Wahyudi   +2 more
doaj   +1 more source

Bioactivity‐Guided Isolation of β‐Sitosterol From Terminalia glabrescens as a Potent Anti‐Zika Virus Agent

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Zika virus (ZIKV) infection remains a global health concern due to its neurological complications and the lack of specific drugs or vaccines. This study investigated the anti‐ZIKV potential of an ethanolic extract from Terminalia glabrescens leaves.
Rosângela Santos Pereira, Priscilla Rodrigues Valadares Campana, Vivian Vasconcelos Costa, Vinícius Gonçalves Maltarollo, Rodrigo Maia de Pádua, José Hugo Sousa de Gomes, Grasiely Farias de Sousa, José Dias de Souza Filho, Daniele da Glória de Souza, Mauro Martins Teixeira, Fernão Castro Braga   +10 more
wiley   +1 more source

Valorization of Mexican Rambutan Peel through the Recovery of Ellagic Acid via Solid-State Fermentation Using a Yeast

Fermentation, 2023
Rambutan (Nephelium lappaceum L.) is a tropical fruit that is originally from Southeast Asia and it was introduced to Mexico in the 1960s; the fruit’s peel is known to possess ellagitannins such as ellagic acid which give the peel great biological ...
Karen De La Rosa-Esteban, Leonardo Sepúlveda, Mónica L. Chávez-González, Cristian Torres-León, Luis E. Estrada-Gil, Cristóbal N. Aguilar, Juan A. Ascacio-Valdés   +6 more
doaj   +1 more source