Results 71 to 80 of about 1,591 (162)

Ellagitannin Profiling, Antioxidant Activity, and BACE1 Inhibitory Potential of Pomegranate Fruit (Punica granatum L.) Peel and Juice: A Comparative Study

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Alzheimer’s disease (AD) is the leading cause of dementia worldwide and remains incurable due to its multifactorial pathophysiology. Punica granatum L. (pomegranate) has attracted interest as a functional food with neuroprotective potential; however, comparative evidence on the bioactivity of its peel and juice remains limited. This study comparatively
Tebalelo Lehlaleroa, Chika I. Chukwuma, Nomonde Mapasa, Muriel Mari, Samson S. Mashele, Claudia Ntsapi-Combrink   +5 more
wiley   +1 more source

Cytotoxic Effects of Compounds Isolated from Ricinodendron heudelotii

Molecules, 2019
This study was designed to explore the in vitro anticancer effects of the bioactive compounds isolated from Ricinodendron heudelotii on selected cancer cell lines.
Omolara F. Yakubu, Abiodun H. Adebayo, Titilope M. Dokunmu, Ying-Jun Zhang, Emeka E.J. Iweala   +4 more
doaj   +1 more source

HPLC Profile of Longan (cv. Shixia) Pericarp-Sourced Phenolics and Their Antioxidant and Cytotoxic Effects

Molecules, 2019
Longan (Dimocarpus longan Lour.) pericarp, the main by-product of aril and pulp processing, is abundant in phenolic compounds and worthy of further utilization. The present work firstly reported HPLC analysis and in vitro antioxidant evaluation of longan
Xuelian Bai, Rui Pan, Mingzhu Li, Xiuting Li, Huawei Zhang   +4 more
doaj   +1 more source

Anti-inflammatory and antioxidant activities of fractions and compound from Ricinodendron heudelotii (Baill.)

Heliyon, 2019
Medicinal plants have been documented over the years to play vital role in promoting human health. The study evaluated the anti-inflammatory and anti-oxidant activities of different fractions and isolated compound from Ricinodendron heudelotii leaves ...
Omolara F. Yakubu, Abiodun H. Adebayo, Emeka E.J. Iweala, Isaacson B. Adelani, Temitope A. Ishola, Ying-Jun Zhang   +5 more
doaj   +1 more source

Polyphenols and Alkaloids in Byproducts of Longan Fruits (Dimocarpus Longan Lour.) and Their Bioactivities

Molecules, 2019
The longan industry produces a large amount of byproducts such as pericarp and seed, resulting in environmental pollution and resource wastage. The present study was performed to systematically evaluate functional components, i.e., polyphenols (phenolics
Ya-Yuan Tang, Xue-Mei He, Jian Sun, Chang-Bao Li, Li Li, Jin-Feng Sheng, Ming Xin, Zhi-Chun Li, Feng-Jin Zheng, Guo-Ming Liu, Jie-Min Li, Dong-Ning Ling   +11 more
doaj   +1 more source

Corilagin alleviates ferroptosis in diabetic retinopathy by activating the Nrf2 signaling pathway

Biomedicine & Pharmacotherapy
Diabetic retinopathy (DR) is a prevalent complication of diabetes, with a rising global incidence, and can result in significant vision impairment and potential blindness in adults. Corilagin (COR) has been shown to regulate several pathological processes.
Wenxin, Shi, Yuchen, Dong, Shuyan, Liu, Fengji, Li, Chao, Zhu   +4 more
openaire   +2 more sources

High-Resolution LC-MS Simultaneous Quantification of Forty-Six Compounds from Jatropha podagrica Fruit Recommends Four Top Antioxidant Contributors as Q-Markers

Molecules
There has been no chemical analysis of the fruit of medicinal plant Jatropha podagrica until now. The current study aimed to qualitatively and quantitatively analyze the J.
Rongxin Cai, Xican Li, Honghong Liang, Shaoman Chen, Yuting Huang, Hanxiao Chai, Rongrong Lin, Guihua Jiang   +7 more
doaj   +1 more source

Corilagin suppresses cholangiocarcinoma progression through Notch signaling pathway in vitro and in vivo

International Journal of Oncology, 2016
Corilagin is a natural plant polyphenol tannic acid with antitumor, anti-inflammatory, and anti-oxidative properties. However, the mechanisms of its actions are largely unknown. Our group reported that corilagin could induce cell inhibition in human breast cancer cell line MCF-7 and human liver hepatocellular carcinoma cell lines HepG2.
GU, YUE, XIAO, LINFENG, MING, YANLIN, ZHENG, ZHIZHONG, LI, WENGANG   +4 more
openaire   +3 more sources

Corilagin sensitizes epithelial ovarian cancer to chemotherapy by inhibiting Snail-glycolysis pathways

Oncology Reports, 2017
We identified that corilagin is a major component extracted from a well-known hepatoprotective and antiviral medicinal herb, Phyllanthus niruri L with antitumor activity. Our previous study found that corilagin inhibited the growth of ovarian cancer cells via the TGF-β/AKT/ERK signaling pathways.
Luoqi, Jia, Jiayi, Zhou, Hongbo, Zhao, Hongyan, Jin, Minzhi, Lv, Naiqing, Zhao, Zhizhong, Zheng, Yiling, Lu, Yanlin, Ming, Yinhua, Yu   +9 more
openaire   +3 more sources

In Vitro Inhibitory Activity of Corilagin and Punicalagin Against Toxoplasma gondii and Their Mechanism(s) of Action

Antibiotics
Background/Objectives: Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. The parasite infection in humans continues to rise due to an increasing seroprevalence rate in domestic and wild warm-blooded animals that serve as a major reservoir ...
Nicole T. Green-Ross, Homa Nath Sharma, Audrey Napier, Boakai K. Robertson, Robert L. Green, Daniel A. Abugri   +5 more
doaj   +1 more source