Results 81 to 90 of about 1,591 (162)

An Integrated Workflow for Activity-Associated Constituent Prioritization and Candidate Quality Marker Evaluation in Complex Herbal Medicines

Chemosensors
Herbal medicines (HMs) are chemically complex multi-component systems, yet analytical strategies that systematically connect chemical composition, biological activity, target prioritization, and quantitative analysis remain limited.
Xiaojuan Zhou, Hui Zhuge, Bo Ma, Zhiwei Ge, Li Che, Lihua Yang, Xiyi Chen, Cheng Jiang, Shujing Zhang, Han Wang, Yingchao Wang, Xiao Li, Yu Tang   +12 more
doaj   +1 more source

In-silico and in-vitro studies to identify potential inhibitors of SARS-CoV-2 spike protein from Omani medicinal plants

Heliyon
In the quest for novel therapeutic agents against SARS-CoV-2, the proposed study explores the potential of traditional Omani medicinal plants, focusing on the efficacy of natural ligands against the virus's Spike protein.
Nabras Al-Mahrami, Smitha Sunil Kumaran Nair, Adhra Al Mawali, Raja-Mohamed Beema Shafreen, Saeed Ullah, Sobia Ahsan Halim, Ahmed Al-Harrasi, Nallusamy Sivakumar   +7 more
doaj   +1 more source

Mutant-Selective Binding of <i>Phyllanthus niruri</i> Phytochemicals to EGFR T790M: A Quantum-Classical Mechanistic Study. [PDF]

Int J Mol Sci
Lituma-González WD, Dinesh Kumar D, Arunprasad AV, Verma T, Pillai S, Jimenez FR, Mahalingam SJ, Lakshmanan S.   +7 more
europepmc   +1 more source

Vascular endothelial protective effects of longan (<i>Dimocarpus longan Lour</i>.) extract and underlying molecular mechanisms. [PDF]

Front Pharmacol
Liu W, Sun R, Li Y, Zhu Y, Zhang L, Jiang F.   +5 more
europepmc   +1 more source

Natural Ellagitannins as Potential Therapeutic Agents for Metabolic Syndrome-Related Disorders. [PDF]

Foods
Chukwuma CI, Mapasa NP, Olusola LT, Kgasapane LP.   +3 more
europepmc   +1 more source

Potentiation of Penicillin G and Selected β-Lactams with Quercetin Against Multidrug-Resistant Bacteria: Mechanistic Insights, Antibacterial Phytochemicals, and Toxicity Evaluation. [PDF]

Int J Mol Sci
Tiwana G, Cock IE, Cheesman MJ.
europepmc   +1 more source

Corilagin induces apoptosis in glioblastoma cells by disrupting metabolic homeostasis: a metabolomics perspective. [PDF]

Naturwissenschaften
Liu F, Zhang M, Long Q, Xiao Y, Ma Q, Han B, Gao Y, Liang Z, Lu Y.   +8 more
europepmc   +1 more source

Transcriptome signature for host directed antiviral reprogramming by Nimba & Triphala in macrophage Dengue virus infection models. [PDF]

Sci Rep
Chakraborty D, Namitha R, Roy R, Devi KL.   +3 more
europepmc   +1 more source

Serum Pharmacochemistry Combined With Network Pharmacology to Explore Potential Bioactive Components and Mechanisms of Pomegranate Peel in the Treatment of Colorectal Cancer. [PDF]

Biomed Chromatogr
Yisimayili Z, Yimamu G, Aimaiti R, Aikemu M, Yunusi K.   +4 more
europepmc   +1 more source

High-throughput automated molecular replacement for small-molecule MicroED data. [PDF]

IUCrJ
Thibodeaux A, Bu G, Edwards LC, Rova Danelius E.   +3 more
europepmc   +1 more source