Results 61 to 70 of about 797 (162)

Applications and advancements in animal models for antiviral research on mosquito‐borne arboviruses

Animal Models and Experimental Medicine, Volume 7, Issue 5, Page 673-684, October 2024.
Animal models are crucial in antiviral research on mosquito‐borne arboviruses, playing a role in understanding disease mechanisms, vaccine development, and toxicity testing. The use of animal models confronts hurdles related to ethical considerations and the successful translation of findings from animals to humans.
Megan Caifeng Tang, Ka Heng Wong, Adzzie Shazleen Azman, Rafidah Lani   +3 more
wiley   +1 more source

Nutrient conditions influence allelopathic capabilities of Ludwigia adscendens and other tropical macrophytes against Microcystis aeruginosa

Freshwater Biology, Volume 69, Issue 4, Page 538-555, April 2024.
Abstract Macrophytes may release allelochemicals that suppress competing phytoplankton, although it is unclear how their effectiveness could be influenced by environmental nutrient conditions. To approach this, we conducted a series of bioassays against the bloom‐forming cyanobacterium Microcystis aeruginosa using extracts and exudates from potentially
Darren Z. H. Sim, Maxine A. D. Mowe, Simon M. Mitrovic, Nikhil K. Tulsian, Ganesh S. Anand, Darren C. J. Yeo   +5 more
wiley   +1 more source

High intraspecific variability and previous experience affect polyphenol metabolism in polyphagous Lymantria mathura caterpillars

Ecology and Evolution, Volume 14, Issue 2, February 2024.
We studied polyphenol metabolism in polyphagous caterpillars of Lymantria mathura (Erebidae, Lepidoptera) to explore mechanisms that may contribute to its ability to feed on various host‐plants. We detected pronounced intraspecific variation in polyphenol metabolism, an ability to excrete ingested metabolites and potential dietary habituation.
Martin Volf, Alyssa M. Fontanilla, Suvi Vanhakylä, Tomokazu Abe, Martin Libra, Ryosuke Kogo, Roll Lilip, Naoto Kamata, Masashi Murakami, Vojtech Novotny, Juha‐Pekka Salminen, Simon T. Segar   +11 more
wiley   +1 more source

Antioxidant and Cytoprotective Effects of an Ethanol Extract of var. from Malaysia

Natural Product Communications, 2013
In the annals of biomedical theory perhaps no single class of natural product has enjoyed more ingenious speculation than antioxidants formally aimed at counteracting oxidative insults which are involved in the pathophysiology of Alzheimer's and ...
Wardah M. Din, Jessica Chu, Garry Clarke, Khoo T. Jin, Tracey D. Bradshaw, Jeff R. Fry, Christophe Wiart   +6 more
doaj   +1 more source

Toxicological Evaluation of a Polyherbal Formulation (18KHT01) and Validation of UPLC‐DAD Method for Quality Control

BioMed Research International, Volume 2024, Issue 1, 2024.
Background: 18KHT01 is a novel synergistic composition of Quercus acutissima, Camellia sinensis, Geranium thunbergii, and a small portion of Citrus limon. Our previous report demonstrated that the 18KHT01 exhibits potent antiobesity effects, with synergistic antioxidant, antiadipogenic, and antiobesity activities in diet‐induced obese mice.
Prakash Raj Pandeya, Ramakanta Lamichhane, Gopal Lamichhane, Kyung-Hee Lee, Hyun-Ju Jung, Devanand P. Fulzele   +5 more
wiley   +1 more source

A Comprehensive Review on Potential In Silico Screened Herbal Bioactive Compounds and Host Targets in the Cardiovascular Disease Therapy

BioMed Research International, Volume 2024, Issue 1, 2024.
Herbal medicines (HMs) have deciphered indispensable therapeutic effects against cardiovascular disease (CVD) (the predominant cause of death worldwide). The conventional CVD therapy approaches have not been efficient and need alternative medicines. The objective of this study was a review of herbal bioactive compound efficacy for CVD therapy based on ...
Elham Zarenezhad, Ali Tareq Hadi, Ensieh Nournia, Sadegh Rostamnia, Abdolmajid Ghasemian, Andrey Cherstvy   +5 more
wiley   +1 more source

Elaeocarpusin, a proto-type of geraniin from Geranium thunbergii.

Chemical and Pharmaceutical Bulletin, 1986
The co-occurrence of geraniin (2) and a novel ellagitannin, elaeocarpusin (1) in Geranium thunbergii has been demonstrated. In addition, enzymatic transformation of 1 into 2 has been achieved, leading to the evidence that dehydroascorbic acid (4) participates as a co-enzyme in the oxidative metabolism of the hexahydroxydiphenoyl group to the ...
Nonaka, Gen-ichiro, Morimoto, Satoshi, Nishioka, Itsuo   +2 more
openaire   +2 more sources

Enhancing the Bioavailability of the Ellagitannin, Geraniin: Formulation, Characterization, and in vivo Evaluation

International Journal of Pharmaceutics
Geraniin (GE), an ellagitannin (ET) renowned for its promising health advantages, faces challenges in its practical applications due to its limited bioavailability. This innovative and novel formulation of GE and soy-phosphatidylcholine (GE-PL) complex has the potential to increase oral bioavailability, exhibiting high entrapment efficiency of 100.2 ...
Sumita, Elendran, V, Shiva Kumar, Usha, Sundralingam, Wai-Kit, Tow, Uma Devi, Palanisamy   +4 more
openaire   +2 more sources

Ellagitannins from and

Natural Product Communications, 2010
The aerial parts of Geranium potentillaefoium afforded geraniin ( 1 ), corilagin ( 2 ), gallic acid ( 4 ), methyl gallate ( 6 ), methyl brevifolincarboxylate ( 7 ), quercetin, quercetin 3- O -β-D-glucopyranoside, quercetin 3- O -β-D-[6″- O -galloyl ...
Juan A. Gayosso-De-Lucio, J. Martín Torres-Valencia, Carlos M. Cerda-García-Rojas, Pedro Joseph-Nathan   +3 more
doaj   +1 more source

Antioxidative Role of Geraniin in Lipid Peroxidation of Human LDL

Journal of Life Science, 2004
Crowing evidence indicates that oxidized low density lipoprotein (LDL) nay promote atherogenesis. Therefore, inhibition of LDL oxidation may impede this process. The effect of geraniin on the susceptibility of human low density lipoprotein (LDL) to macrophages-induced oxidation was investigated by monitoring a thiobarbiruric acid reactive substrance ...
openaire   +2 more sources